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Related papers: CTP-LLM: Clinical Trial Phase Transition Predictio…

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Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

Computation and Language · Computer Science 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

Extracting MITRE ATT\&CK Tactics, Techniques, and Procedures (TTPs) from natural language threat reports is crucial yet challenging. Existing methods primarily focus on performance metrics using data-driven approaches, often neglecting…

Cryptography and Security · Computer Science 2025-05-15 Cheng Meng , ZhengWei Jiang , QiuYun Wang , XinYi Li , ChunYan Ma , FangMing Dong , FangLi Ren , BaoXu Liu

Managing scan protocols in Computed Tomography (CT), which includes adjusting acquisition parameters or configuring reconstructions, as well as selecting postprocessing tools in a patient-specific manner, is time-consuming and requires…

Artificial Intelligence · Computer Science 2025-09-25 Xingjian Kang , Linda Vorberg , Andreas Maier , Alexander Katzmann , Oliver Taubmann

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation across various domains, including medicine. We present a comprehensive evaluation of GPT-4, a state-of-the-art LLM, on…

Computation and Language · Computer Science 2023-04-13 Harsha Nori , Nicholas King , Scott Mayer McKinney , Dean Carignan , Eric Horvitz

The recent success of large language models (LLMs) has shown great potential to develop more powerful conversational recommender systems (CRSs), which rely on natural language conversations to satisfy user needs. In this paper, we embark on…

Computation and Language · Computer Science 2024-06-21 Xiaolei Wang , Xinyu Tang , Wayne Xin Zhao , Jingyuan Wang , Ji-Rong Wen

Flight trajectory prediction is a critical time series task in aviation. While deep learning methods have shown significant promise, the application of large language models (LLMs) to this domain remains underexplored. This study pioneers…

Artificial Intelligence · Computer Science 2025-01-30 Kaiwei Luo , Jiliu Zhou

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson

Large Language Models (LLMs) have recently emerged as planners for language-instructed agents, generating sequences of actions to accomplish natural language tasks. However, their reliability remains a challenge, especially in long-horizon…

Robotics · Computer Science 2025-11-11 Jun Wang , Yevgeniy Vorobeychik , Yiannis Kantaros

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Clinical Decision Support Systems (CDSS) utilize evidence-based knowledge and patient data to offer real-time recommendations, with Large Language Models (LLMs) emerging as a promising tool to generate plain-text explanations for medical…

Computation and Language · Computer Science 2023-10-04 D. Umerenkov , G. Zubkova , A. Nesterov

The rapid proliferation of large language models (LLMs) in healthcare creates an urgent need for scalable and psychometrically sound evaluation methods. Conventional static benchmarks are costly to administer repeatedly, vulnerable to data…

Computation and Language · Computer Science 2026-03-26 Tianpeng Zheng , Zhehan Jiang , Jiayi Liu , Shicong Feng

As large language models (LLMs) like ChatGPT exhibited unprecedented machine intelligence, it also shows great performance in assisting hardware engineers to realize higher-efficiency logic design via natural language interaction. To…

Artificial Intelligence · Computer Science 2025-10-14 Kaiyan Chang , Ying Wang , Haimeng Ren , Mengdi Wang , Shengwen Liang , Yinhe Han , Huawei Li , Xiaowei Li

Large Language Models (LLMs) have drawn a lot of attention due to their strong performance on a wide range of natural language tasks, since the release of ChatGPT in November 2022. LLMs' ability of general-purpose language understanding and…

Computation and Language · Computer Science 2025-03-25 Shervin Minaee , Tomas Mikolov , Narjes Nikzad , Meysam Chenaghlu , Richard Socher , Xavier Amatriain , Jianfeng Gao

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

The new transmission control protocol (TCP) relies on Deep Learning (DL) for prediction and optimization, but requires significant manual effort to design deep neural networks (DNNs) and struggles with generalization in dynamic…

Networking and Internet Architecture · Computer Science 2024-12-25 Shyam Kumar Shrestha , Shiva Raj Pokhrel , Jonathan Kua

Safety- and security-critical systems have to be thoroughly tested against their specifications. The state of practice is to have _natural language_ specifications, from which test cases are derived manually - a process that is slow,…

Software Engineering · Computer Science 2025-11-25 Kuangxiangzi Liu , Dhiman Chakraborty , Alexander Liggesmeyer , Andreas Zeller

This study introduces a novel approach for traffic control systems by using Large Language Models (LLMs) as traffic controllers. The study utilizes their logical reasoning, scene understanding, and decision-making capabilities to optimize…

Computation and Language · Computer Science 2024-11-19 Sari Masri , Huthaifa I. Ashqar , Mohammed Elhenawy

We explore the usage of large language models (LLM) in human-in-the-loop human-in-the-plant cyber-physical systems (CPS) to translate a high-level prompt into a personalized plan of actions, and subsequently convert that plan into a…

Artificial Intelligence · Computer Science 2024-05-21 Ayan Banerjee , Aranyak Maity , Payal Kamboj , Sandeep K. S. Gupta
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