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In this work, we propose a new deep learning model for Genomic Prediction (GP), which involves correlating genotypic data with phenotypic. The genotypes are typically fed as a sequence of characters to the 1D-Convolution Neural Network…

Machine Learning · Computer Science 2026-03-03 Kuldeep Pathak , Kapil Ahuja , Eric de Sturler

Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, fitting mvLMMs is computationally non-trivial,…

Quantitative Methods · Quantitative Biology 2013-09-13 Xiang Zhou , Matthew Stephens

Inferring missing links or detecting spurious ones based on observed graphs, known as link prediction, is a long-standing challenge in graph data analysis. With the recent advances in deep learning, graph neural networks have been used for…

Social and Information Networks · Computer Science 2023-01-03 Xingping Xian , Tao Wu , Xiaoke Ma , Shaojie Qiao , Yabin Shao , Chao Wang , Lin Yuan , Yu Wu

In this work, we propose the Generative Latent Flow (GLF), an algorithm for generative modeling of the data distribution. GLF uses an Auto-encoder (AE) to learn latent representations of the data, and a normalizing flow to map the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Zhisheng Xiao , Qing Yan , Yali Amit

Mixup is a data augmentation method that generates new data points by mixing a pair of input data. While mixup generally improves the prediction performance, it sometimes degrades the performance. In this paper, we first identify the main…

Machine Learning · Computer Science 2022-01-10 Jy-yong Sohn , Liang Shang , Hongxu Chen , Jaekyun Moon , Dimitris Papailiopoulos , Kangwook Lee

Branch-and-Bound (B\&B) is an exact method in integer programming that recursively divides the search space into a tree. During the resolution process, determining the next subproblem to explore within the tree-known as the search…

Machine Learning · Computer Science 2024-12-18 Gwen Maudet , Grégoire Danoy

Traditional genetic programming (GP) often struggles in stock alpha factor discovery due to its vast search space, overwhelming computational burden, and sporadic effective alphas. We find that GP performs better when focusing on promising…

Statistical Finance · Quantitative Finance 2024-12-03 Weizhe Ren , Yichen Qin , Yang Li

In recent years, graph neural networks (GNNs) have gained increasing attention, as they possess the excellent capability of processing graph-related problems. In practice, hyperparameter optimisation (HPO) is critical for GNNs to achieve…

Machine Learning · Computer Science 2021-04-29 Yingfang Yuan , Wenjun Wang , Wei Pang

Large Language Models (LLMs) excel in general tasks, but adapting them to specialized domains relies on high-quality supervised fine-tuning (SFT) data. Although existing methods can identify subsets of high-quality data and reduce training…

Computation and Language · Computer Science 2025-10-17 Zhaoyang Shang , Sibo Wei , Jianbin Guo , Rui Zhou , Lifeng Dong , Yin Luo

Grammar-Guided Genetic Programming (GGGP) employs a variety of insights from evolutionary theory to autonomously design solutions for a given task. Recent insights from evolutionary biology can lead to further improvements in GGGP…

Neural and Evolutionary Computing · Computer Science 2023-07-13 Stefano Tiso , Pedro Carvalho , Nuno Lourenço , Penousal Machado

We forecast a single time series using a high-dimensional set of predictors. When these predictors share common underlying dynamics, an approximate latent factor model provides a powerful characterization of their co-movements Bai(2003).…

Econometrics · Economics 2025-12-11 Rajveer Jat , Daanish Padha

With the demand for machine learning increasing, so does the demand for tools which make it easier to use. Automated machine learning (AutoML) tools have been developed to address this need, such as the Tree-Based Pipeline Optimization Tool…

Neural and Evolutionary Computing · Computer Science 2018-03-13 Pieter Gijsbers , Joaquin Vanschoren , Randal S. Olson

Multi-fidelity (MF) methods are gaining popularity for enhancing surrogate modeling and design optimization by incorporating data from various low-fidelity (LF) models. While most existing MF methods assume a fixed dataset, adaptive…

Machine Learning · Statistics 2024-02-06 Yi-Ping Chen , Liwei Wang , Yigitcan Comlek , Wei Chen

Relational databases, organized into tables connected by primary-foreign key relationships, are a common format for organizing data. Making predictions on relational data often involves transforming them into a flat tabular format through…

Databases · Computer Science 2025-04-08 Veronica Lachi , Antonio Longa , Beatrice Bevilacqua , Bruno Lepri , Andrea Passerini , Bruno Ribeiro

For classification and regression on tabular data, the dominance of gradient-boosted decision trees (GBDTs) has recently been challenged by often much slower deep learning methods with extensive hyperparameter tuning. We address this…

Machine Learning · Computer Science 2025-01-16 David Holzmüller , Léo Grinsztajn , Ingo Steinwart

Gradient Boosted Decision Trees (GBDTs) are widely used for building ranking and relevance models in search and recommendation. Considerations such as latency and interpretability dictate the use of as few features as possible to train…

Machine Learning · Statistics 2021-09-07 Cuize Han , Nikhil Rao , Daria Sorokina , Karthik Subbian

Identifying transcription factor binding sites (TFBS) is crucial for understanding gene regulation, as these sites enable transcription factors (TFs) to bind to DNA and modulate gene expression. Despite advances in high-throughput…

Machine Learning · Computer Science 2025-03-18 Jonas Chris Ferrao , Dickson Dias , Sweta Morajkar , Manisha Gokuldas Fal Dessai

A prominent goal of representation learning research is to achieve representations which are factorized in a useful manner with respect to the ground truth factors of variation. The fields of disentangled and equivariant representation…

Machine Learning · Computer Science 2023-09-26 Yue Song , T. Anderson Keller , Nicu Sebe , Max Welling

In this study, we develop a latent factor model for analysing high-dimensional binary data. Specifically, a standard probit model is used to describe the regression relationship between the observed binary data and the continuous latent…

Methodology · Statistics 2024-04-15 Jiaxin Shi , Yuan Gao , Rui Pan , Hansheng Wang

Graph Neural Networks (GNNs) are powerful learning methods for recommender systems owing to their robustness in handling complicated user-item interactions. Recently, the integration of contrastive learning with GNNs has demonstrated…

Machine Learning · Computer Science 2024-08-12 Junfeng Long , Hao Wu