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This paper introduces a novel approach to creating adaptive language agents by integrating active inference with large language models (LLMs). While LLMs demonstrate remarkable capabilities, their reliance on static prompts limits…

Computation and Language · Computer Science 2025-01-13 Rithvik Prakki

Spatial transcriptomics assays are rapidly increasing in scale and complexity, making computational analysis a major bottleneck in biological discovery. Although frontier AI agents have improved dramatically at software engineering and…

Artificial Intelligence · Computer Science 2026-01-06 Kenny Workman , Zhen Yang , Harihara Muralidharan , Hannah Le

We introduce MLRC-Bench, a benchmark designed to quantify how effectively language agents can tackle challenging Machine Learning (ML) Research Competitions, with a focus on open research problems that demand novel methodologies. Unlike…

Data analysis has become an indispensable part of scientific research. To discover the latent knowledge and insights hidden within massive datasets, we need to perform deep exploratory analysis to realize their full value. With the advent…

Artificial Intelligence · Computer Science 2026-05-29 Zhenghao Zhu , Yuanfeng Song , Xin Chen , Chengzhong Liu , Yakun Cui , Caleb Chen Cao , Sirui Han , Yike Guo

We introduce DRBench, a benchmark for evaluating AI agents on complex, open-ended deep research tasks in enterprise settings. Unlike prior benchmarks that focus on simple questions or web-only queries, DRBench evaluates agents on multi-step…

The advent of large language models (LLMs) has catalyzed a transformative shift in artificial intelligence, paving the way for advanced intelligent agents capable of sophisticated reasoning, robust perception, and versatile action across…

We present PULSE, a medical reasoning agent that combines a domain-tuned large language model with scientific literature retrieval to support diagnostic decision-making in complex real-world cases. To evaluate its capabilities, we curated a…

Computation and Language · Computer Science 2026-03-19 Zhongzhen Huang , Yan Ling , Hong Chen , Ye Feng , Li Wu , Linjie Mu , Shaoting Zhang , Xiaofan Zhang , Kun Qian , Xiaomu Li

Agents powered by Large Language Models (LLMs) have recently demonstrated impressive capabilities in various tasks. Still, they face limitations in tasks requiring specific, structured knowledge, flexibility, or accountable decision-making.…

Artificial Intelligence · Computer Science 2025-04-14 Kostas Hatalis , Despina Christou , Vyshnavi Kondapalli

Traditional methods for system discovery frequently struggle with efficient data usage and uncertainty quantification. Identifying the governing equations of complex dynamical systems from data presents a significant challenge in scientific…

Machine Learning · Statistics 2026-04-14 Cindy Xiangrui Kong , Haoyang Zheng , Guang Lin

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Information retrieval is a cornerstone of modern knowledge acquisition, enabling billions of queries each day across diverse domains. However, traditional keyword-based search engines are increasingly inadequate for handling complex,…

Embodied agents operating in multi-agent, partially observable, and decentralized environments must plan and act despite pervasive uncertainty about hidden objects and collaborators' intentions. Recent advances in applying Large Language…

Artificial Intelligence · Computer Science 2026-02-05 SeungWon Seo , SooBin Lim , SeongRae Noh , Haneul Kim , HyeongYeop Kang

Large language model (LLM) agents currently depend on predefined tools or early-stage tool generation, limiting their adaptability and scalability to complex scientific tasks. We introduce CASCADE, a self-evolving agentic framework…

Artificial Intelligence · Computer Science 2026-01-29 Xu Huang , Junwu Chen , Yuxing Fei , Zhuohan Li , Philippe Schwaller , Gerbrand Ceder

Large language models (LLMs) have shown potential in assisting scientific research, yet their ability to discover high-quality research hypotheses remains unexamined due to the lack of a dedicated benchmark. To address this gap, we…

Computation and Language · Computer Science 2026-04-21 Yujie Liu , Zonglin Yang , Tong Xie , Jinjie Ni , Ben Gao , Yuqiang Li , Shixiang Tang , Wanli Ouyang , Erik Cambria , Dongzhan Zhou

Web agents enable users to perform tasks on web browsers through natural language interaction. Evaluating web agents trajectories is an important problem, since it helps us determine whether the agent successfully completed the tasks.…

Deep Research Systems (DRS) aim to help users search the web, synthesize information, and deliver comprehensive investigative reports. However, how to rigorously evaluate these systems remains under-explored. Existing deep-research…

Computation and Language · Computer Science 2026-02-02 Ruizhe Li , Mingxuan Du , Benfeng Xu , Chiwei Zhu , Xiaorui Wang , Zhendong Mao

Large language models (LLMs) hold considerable potential for advancing scientific discovery, yet systematic assessment of their dynamic reasoning in real-world research remains limited. Current scientific evaluation benchmarks predominantly…

Computation and Language · Computer Science 2026-03-27 Taolin Han , Shuang Wu , Jinghang Wang , Yuhao Zhou , Renquan Lv , Bing Zhao , Wei Hu

Large language models (LLMs) have demonstrated remarkable capabilities across a range of text-generation tasks. However, LLMs still struggle with problems requiring multi-step decision-making and environmental feedback, such as online…

Artificial Intelligence · Computer Science 2025-02-18 Zhenfang Chen , Delin Chen , Rui Sun , Wenjun Liu , Chuang Gan

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

The massive successes of large language models (LLMs) encourage the emerging exploration of LLM-augmented Autonomous Agents (LAAs). An LAA is able to generate actions with its core LLM and interact with environments, which facilitates the…

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