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DNA methylation is a well-studied genetic modification crucial to regulate the functioning of the genome. Its alterations play an important role in tumorigenesis and tumor-suppression. Thus, studying DNA methylation data may help biomarker…

Genomics · Quantitative Biology 2018-04-16 Fabrizio Celli , Fabio Cumbo , Emanuel Weitschek

Medical professionals frequently work in a data constrained setting to provide insights across a unique demographic. A few medical observations, for instance, informs the diagnosis and treatment of a patient. This suggests a unique setting…

Computation and Language · Computer Science 2022-12-06 Pankaj Sharma , Imran Qureshi , Minh Tran

Melanoma is one of the ten most common cancers in the US. Early detection is crucial for survival, but often the cancer is diagnosed in the fatal stage. Deep learning has the potential to improve cancer detection rates, but its…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Devansh Bisla , Anna Choromanska , Jennifer A. Stein , David Polsky , Russell Berman

Gene expression data represents a unique challenge in predictive model building, because of the small number of samples $(n)$ compared to the huge amount of features $(p)$. This "$n<<p$" property has hampered application of deep learning…

Machine Learning · Statistics 2018-02-13 Yunchuan Kong , Tianwei Yu

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

Image and Video Processing · Electrical Eng. & Systems 2020-09-17 Yue Liu , Hossein Azizpour , Fredrik Strand , Kevin Smith

We investigate the learning of quantitative structure activity relationships (QSARs) as a case-study of meta-learning. This application area is of the highest societal importance, as it is a key step in the development of new medicines. The…

Artificial Intelligence · Computer Science 2017-09-13 Ivan Olier , Noureddin Sadawi , G. Richard Bickerton , Joaquin Vanschoren , Crina Grosan , Larisa Soldatova , Ross D. King

Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In…

Machine Learning · Computer Science 2021-02-22 del Amor Rocío , Colomer Adrián , Monteagudo Carlos , Naranjo Valery

The field of meta-learning has seen a dramatic rise in interest in recent years. In existing meta-learning approaches, learning tasks for training meta-models are usually collected from public datasets, which brings the difficulty of…

Machine Learning · Computer Science 2021-11-23 Zhaoyang Hai , Xiabi Liu , Yuchen Ren , Nouman Q. Soomro

Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

Artificial Intelligence · Computer Science 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

System identification has greatly benefited from deep learning techniques, particularly for modeling complex, nonlinear dynamical systems with partially unknown physics where traditional approaches may not be feasible. However, deep…

Machine Learning · Computer Science 2025-04-17 Marco Forgione , Ankush Chakrabarty , Dario Piga , Matteo Rufolo , Alberto Bemporad

Machine learning (ML) is a branch of Artificial Intelligence (AI) where computers analyze data and find patterns in the data. The study focuses on the detection of metastatic cancer using ML. Metastatic cancer is the point where the cancer…

Artificial Intelligence · Computer Science 2023-09-20 Bliss Singhal , Fnu Pooja

The objective of many high-dimensional microarray and RNA-seq studies is to develop a classifier of cancer patients based on characteristics of their disease. The germinal center B-cell (GCB) classifier study in lymphoma and the National…

Applications · Statistics 2015-09-17 Sandra Safo , Xiao Song , Kevin K. Dobbin

The limited availability of annotated data presents a major challenge for applying deep learning methods to medical image analysis. Few-shot learning methods aim to recognize new classes from only a small number of labeled examples. These…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Berenice Montalvo-Lezama , Gibran Fuentes-Pineda

Meta learning has attracted much attention recently in machine learning community. Contrary to conventional machine learning aiming to learn inherent prediction rules to predict labels for new query data, meta learning aims to learn the…

Machine Learning · Computer Science 2023-07-04 Jun Shu , Deyu Meng , Zongben Xu

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

Several multi-target regression methods were devel-oped in the last years aiming at improving predictive performanceby exploring inter-target correlation within the problem. However, none of these methods outperforms the others for all…

A proper form of data characterization can guide the process of learning-algorithm selection and model-performance estimation. The field of meta-learning has provided a rich body of work describing effective forms of data characterization…

Machine Learning · Computer Science 2021-02-01 Mikhail M. Meskhi , Adriano Rivolli , Rafael G. Mantovani , Ricardo Vilalta

Children acquire language despite being exposed to several orders of magnitude less data than large language models require. Meta-learning has been proposed as a way to integrate human-like learning biases into neural-network architectures,…

Computation and Language · Computer Science 2025-06-04 Michael Goodale , Salvador Mascarenhas , Yair Lakretz

We propose an algorithm for meta-learning that is model-agnostic, in the sense that it is compatible with any model trained with gradient descent and applicable to a variety of different learning problems, including classification,…

Machine Learning · Computer Science 2017-07-19 Chelsea Finn , Pieter Abbeel , Sergey Levine