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Design-based simulations - procedures that hold realized outcomes fixed and generate variation by resampling treatment assignment or shocks - are widely used in both methodological and applied work to assess inference procedures. This paper…

Econometrics · Economics 2026-03-13 Bruno Ferman

Pricing decisions of companies require an understanding of the causal effect of a price change on the demand. When real-life pricing experiments are infeasible, data-driven decision-making must be based on alternative data sources such as…

Applications · Statistics 2024-07-03 Lauri Valkonen , Santtu Tikka , Jouni Helske , Juha Karvanen

The increasing recognition of the association between adverse human health conditions and many environmental substances as well as processes has led to the need to monitor them. An important problem that arises in environmental statistics…

Applications · Statistics 2020-02-05 Yu Wang , Nhu D. Le , James V. Zidek

Over the past two decades, the rapid surge in data-intensive computational techniques for statistical modeling may have had the effect of diminishing the use of applied mathematics in causal scientific inquiry. In this paper, co-authored by…

History and Philosophy of Physics · Physics 2026-05-13 Marzieh Asgari-Targhi , Amene Asgari-Targhi , Mahboubeh Asgari-Targhi , Edward J. , Hall

Large language model (LLM) development is currently driven by large-scale empirical iteration over data mixtures, reward models, routing strategies, and evaluation pipelines. Here, we argue that many central questions in LLM development and…

Causal inference is often portrayed as fundamentally distinct from predictive modeling, with its own terminology, goals, and intellectual challenges. But at its core, causal inference is simply a structured instance of prediction under…

Machine Learning · Computer Science 2025-07-10 Carlos Fernández-Loría

In experimental design, we are given $n$ vectors in $d$ dimensions, and our goal is to select $k\ll n$ of them to perform expensive measurements, e.g., to obtain labels/responses, for a linear regression task. Many statistical criteria have…

Machine Learning · Computer Science 2019-06-11 Michał Dereziński , Feynman Liang , Michael W. Mahoney

There is a movement in design of experiments away from the classic randomization put forward by Fisher, Cochran and others to one based on optimization. In fixed-sample trials comparing two groups, measurements of subjects are known in…

Methodology · Statistics 2018-10-22 Adam Kapelner , Abba M. Krieger , Uri Shalit , David Azriel

Empirical software engineering is concerned with the design and analysis of empirical studies that include software products, processes, and resources. Optimization is a form of data analytics in support of human decision-making.…

Software Engineering · Computer Science 2019-12-05 Guenther Ruhe

Numerical predictions of quantities of interest measured within physical systems rely on the use of mathematical models that should be validated, or at best, not invalidated. Model validation usually involves the comparison of experimental…

Computational Engineering, Finance, and Science · Computer Science 2023-07-19 Antonin Paquette-Rufiange , Serge Prudhomme , Marc Laforest

We describe basic ideas underlying research to build and understand artificially intelligent systems: from symbolic approaches via statistical learning to interventional models relying on concepts of causality. Some of the hard open…

Artificial Intelligence · Computer Science 2022-04-04 Bernhard Schölkopf , Julius von Kügelgen

Causal learning has garnered significant attention in recent years because it reveals the essential relationships that underpin phenomena and delineates the mechanisms by which the world evolves. Nevertheless, traditional causal learning…

Machine Learning · Computer Science 2024-07-31 Zizhen Deng , Xiaolong Zheng , Hu Tian , Daniel Dajun Zeng

Causal models bring many benefits to decision-making systems (or agents) by making them interpretable, sample-efficient, and robust to changes in the input distribution. However, spurious correlations can lead to wrong causal models and…

Machine Learning · Computer Science 2020-12-09 Sergei Volodin , Nevan Wichers , Jeremy Nixon

Discontinuities can be fairly arbitrary but also cause a significant impact on outcomes in larger systems. Indeed, their arbitrariness is why they have been used to infer causal relationships among variables in numerous settings. Regression…

Information Theory · Computer Science 2023-12-29 Ibtihal Ferwana , Suyoung Park , Ting-Yi Wu , Lav R. Varshney

This paper serves as a literature review of methodology concerning the (modern) causal inference methods to address the causal estimand with observational/survey data that have been or will be used in social science research. Mainly, this…

Econometrics · Economics 2024-08-02 Guanghui Pan

Data-driven design is making headway into a number of application areas, including protein, small-molecule, and materials engineering. The design goal is to construct an object with desired properties, such as a protein that binds to a…

Machine Learning · Computer Science 2025-04-04 Clara Fannjiang , Jennifer Listgarten

Excellent computer simulations are done for a purpose. The most valid purposes are to explore uncharted territory, to resolve a well-posed scientific or technical question, or to make a design choice. Stand-alone modeling can serve the…

Numerical Analysis · Mathematics 2025-10-20 Leo P. Kadanoff

Recommender systems have become crucial in information filtering nowadays. Existing recommender systems extract user preferences based on the correlation in data, such as behavioral correlation in collaborative filtering, feature-feature,…

Information Retrieval · Computer Science 2023-12-18 Chen Gao , Yu Zheng , Wenjie Wang , Fuli Feng , Xiangnan He , Yong Li

This paper reviews the design of experiments for generalised linear models, including optimal design, Bayesian design and designs for models with random effects.

Methodology · Statistics 2015-10-20 Anthony C. Atkinson , David C. Woods

Unbiased and consistent variance estimators generally do not exist for design-based treatment effect estimators because experimenters never observe more than one potential outcome for any unit. The problem is exacerbated by interference and…

Methodology · Statistics 2024-07-04 Christopher Harshaw , Joel A. Middleton , Fredrik Sävje