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There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Electrocardiograms (ECG), which record the electrophysiological activity of the heart, have become a crucial tool for diagnosing these diseases. In recent years, the application of deep learning techniques has significantly improved the…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Wei Huang , Ning Wang , Panpan Feng , Haiyan Wang , Zongmin Wang , Bing Zhou

Domain-adapted open-weight large language models (LLMs) offer promising healthcare applications, from queryable knowledge bases to multimodal assistants, with the crucial advantage of local deployment for privacy preservation. However,…

Computation and Language · Computer Science 2025-10-22 Lara Ahrens , Wilhelm Haverkamp , Nils Strodthoff

In the past year, there has been a growing trend in applying Large Language Models (LLMs) to the field of medicine, particularly with the advent of advanced language models such as ChatGPT developed by OpenAI. However, there is limited…

Computation and Language · Computer Science 2024-02-27 Fujian Jia , Xin Liu , Lixi Deng , Jiwen Gu , Chunchao Pu , Tunan Bai , Mengjiang Huang , Yuanzhi Lu , Kang Liu

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

Over the last few years, large language models (LLMs) have emerged as the most important breakthroughs in natural language processing (NLP) that fundamentally transform research and developments in the field. ChatGPT represents one of the…

Computation and Language · Computer Science 2023-04-13 Viet Dac Lai , Nghia Trung Ngo , Amir Pouran Ben Veyseh , Hieu Man , Franck Dernoncourt , Trung Bui , Thien Huu Nguyen

Recently, Multimodal Large Language Models (MLLMs) have gained significant attention for their remarkable ability to process and analyze non-textual data, such as images, videos, and audio. Notably, several adaptations of general-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Wenhui Zhu , Xin Li , Xiwen Chen , Peijie Qiu , Vamsi Krishna Vasa , Xuanzhao Dong , Yanxi Chen , Natasha Lepore , Oana Dumitrascu , Yi Su , Yalin Wang

Large Language Models (LLMs) have demonstrated exceptional versatility across domains, including applications to electrocardiograms (ECGs). A growing body of work focuses on generating text from multi-channeled ECG signals and corresponding…

Computation and Language · Computer Science 2025-07-31 William Han , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

This work discusses the use of contrastive learning and deep learning for diagnosing cardiovascular diseases from electrocardiography (ECG) signals. While the ECG signals usually contain 12 leads (channels), many healthcare facilities and…

Signal Processing · Electrical Eng. & Systems 2023-04-24 Tue M. Cao , Nhat H. Tran , Phi Le Nguyen , Hieu Pham

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Early detection of cardiovascular diseases is crucial for effective treatment and an electrocardiogram (ECG) is pivotal for diagnosis. The accuracy of Deep Learning based methods for ECG signal classification has progressed in recent years…

Signal Processing · Electrical Eng. & Systems 2022-04-12 Likith Reddy , Vivek Talwar , Shanmukh Alle , Raju. S. Bapi , U. Deva Priyakumar

Participant recruitment based on unstructured medical texts such as clinical notes and radiology reports has been a challenging yet important task for the cohort establishment in clinical research. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2023-07-24 Zihan Guan , Zihao Wu , Zhengliang Liu , Dufan Wu , Hui Ren , Quanzheng Li , Xiang Li , Ninghao Liu

Electrocardiograms (ECGs) play a vital role in monitoring cardiac health and diagnosing heart diseases. However, traditional deep learning approaches for ECG analysis rely heavily on large-scale manual annotations, which are both…

Signal Processing · Electrical Eng. & Systems 2025-06-30 Fuying Wang , Jiacheng Xu , Lequan Yu

Medical report generation from imaging data remains a challenging task in clinical practice. While large language models (LLMs) show great promise in addressing this challenge, their effective integration with medical imaging data still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Chunlei Li , Jingyang Hou , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

The 12-lead electrocardiogram (ECG) is a quasi-periodic, multi-channel signal with diagnostic content spanning timescales from millisecond waveform morphology to multi-second rhythm dynamics. Existing ECG representation learning relies on…

Computational Engineering, Finance, and Science · Computer Science 2026-05-26 Lei Xu , Fahad Sohrab , Mehmet Yamac , Merja Heinaniemi , Moncef Gabbouj

Speech Language Models (SLMs) have made significant progress in spoken language understanding. Yet it remains unclear whether they can fully perceive non lexical vocal cues alongside spoken words, and respond with empathy that aligns with…

Computation and Language · Computer Science 2026-03-06 Li Zhou , Lutong Yu , You Lyu , Yihang Lin , Zefeng Zhao , Junyi Ao , Yuhao Zhang , Benyou Wang , Haizhou Li

Rapid integration of large language models (LLMs) in health care is sparking global discussion about their potential to revolutionize health care quality and accessibility. At a time when improving health care quality and access remains a…

Computers and Society · Computer Science 2025-04-01 Troy Zada , Natalie Tam , Francois Barnard , Marlize Van Sittert , Venkat Bhat , Sirisha Rambhatla

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

We present Clinical Camel, an open large language model (LLM) explicitly tailored for clinical research. Fine-tuned from LLaMA-2 using QLoRA, Clinical Camel achieves state-of-the-art performance across medical benchmarks among openly…

Computation and Language · Computer Science 2023-08-21 Augustin Toma , Patrick R. Lawler , Jimmy Ba , Rahul G. Krishnan , Barry B. Rubin , Bo Wang

3D medical image analysis is of great importance in disease diagnosis and treatment. Recently, multimodal large language models (MLLMs) have exhibited robust perceptual capacity, strong cross-modal alignment, and promising generalizability.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yang Yu , Dunyuan Xu , Yaoqian Li , Xiaomeng Li , Jinpeng Li , Pheng-Ann Heng
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