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Confocal laser scanning microscopy (CLSM) stands out as one of the most widely used microscopy techniques, thanks to its three-dimensional imaging capability and its sub-diffraction spatial resolution, achieved through the closure of a…

Stochastic resonance describes the utility of noise in improving the detectability of weak signals in certain types of systems. It has been observed widely in natural and engineered settings, but its utility in image classification with…

Computer Vision and Pattern Recognition · Computer Science 2025-02-21 Siegfried Ludwig

Structured illumination microscopy (SIM) is a pivotal technique for dynamic subcellular imaging in live cells. Conventional SIM reconstruction algorithms depend on accurately estimating the illumination pattern and can introduce artefacts…

Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Despite the significant progress in image denoising, it is still challenging to restore fine-scale details while removing noise, especially in extremely low-light environments. Leveraging near-infrared (NIR) images to assist visible RGB…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Rongjian Xu , Zhilu Zhang , Renlong Wu , Wangmeng Zuo

Image denoising is a fundamental problem in computer vision and medical imaging. However, real-world images are often degraded by structured noise with strong anisotropic correlations that existing methods struggle to remove. Most…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Jianxu Wang , Ge Wang

This paper proposes a subspace decomposition method based on an over-complete dictionary in sparse representation, called "Sparse Signal Subspace Decomposition" (or 3SD) method. This method makes use of a novel criterion based on the…

Machine Learning · Statistics 2016-10-28 Hong Sun , Chengwei Sang , Didier Le Ruyet

Denoising is of utmost importance for the visualization and processing of images featuring low signal-to-noise ratio. Total variation methods are among the most popular techniques to perform this task improving the signal-to-noise ratio…

Signal Processing · Electrical Eng. & Systems 2022-01-24 Gonzalo D. Maso Talou , Pablo J. Blanco

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Fluorescence polarization microscopy images both the intensity and orientation of fluorescent dipoles, which plays a vital role in studying the molecular structure and dynamics of bio-complex. However, it is difficult to resolve the dipole…

Structured illumination microscopy (SIM) is one of the most versatile super-resolution techniques. Yet, its application to live imaging has been so far mainly limited to fluorescent and stationary specimens. Here, we present advancements in…

Nanoscale secondary ion mass spectrometry (nanoSIMS) and fluorescence in situ hybridization (FISH) microscopy provide high-resolution, multimodal image representations of the identity and cell activity respectively of targeted microbial…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Xiaojia He , Christof Meile , Suchendra M. Bhandarkar

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

Structured illumination microscopy (SIM) achieves superresolution in fluorescence imaging through patterned illumination and computational image reconstruction, yet current methods require bulky, costly modulation optics and high-precision…

Optics · Physics 2024-04-15 Tamal Roy , Peter T. Brown , Douglas P. Shepherd , Lisa V. Poulikakos

Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-20 Anna S. Goncharova , Alf Honigmann , Florian Jug , Alexander Krull

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Performance measures are an important tool for assessing and comparing different medical image segmentation algorithms. Unfortunately, the current measures have their weaknesses when it comes to assessing certain edge cases. These…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Dennis Hartmann , Verena Schmid , Philip Meyer , Iñaki Soto-Rey , Dominik Müller , Frank Kramer

Noise in image sensors led to the development of a whole range of denoising filters. A noisy image can become hard to recognize and often require several types of post-processing compensation circuits. This paper proposes an adaptive…

Image and Video Processing · Electrical Eng. & Systems 2022-09-27 O. Krestinskaya , K. N. Salama , A. P. James

During the last decade, hyperspectral images have attracted increasing interest from researchers worldwide. They provide more detailed information about an observed area and allow an accurate target detection and precise discrimination of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Asma Elmaizi , Hasna Nhaila , Elkebir Sarhrouni , Ahmed Hammouch , Nacir Chafik