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Random matrix theory has become a widely useful tool in high-dimensional statistics and theoretical machine learning. However, random matrix theory is largely focused on the proportional asymptotics in which the number of columns grows…

Statistics Theory · Mathematics 2025-06-23 Chen Cheng , Andrea Montanari

Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental variables to infer the direct effects of multiple exposures on an outcome. However, unlike univariable Mendelian randomization, MVMR often faces greater…

Methodology · Statistics 2025-08-19 Yinxiang Wu , Hyunseung Kang , Ting Ye

This paper deals with the parameter estimation problem of the Single-Input-Single-Output (SISO) switched Hammerstein system. Suppose that the switching law is arbitrary but can be observed online. All subsystems are parameterized and the…

Systems and Control · Computer Science 2017-05-18 Jing Zhang , Han-Fu Chen

We provide a new flexible framework for inference with the instrumental variable model. Rather than using linear specifications, functions characterizing the effects of instruments and other explanatory variables are estimated using machine…

Machine Learning · Statistics 2021-02-03 Robert E. McCulloch , Rodney A. Sparapani , Brent R. Logan , Purushottam W. Laud

The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potentially unmeasured confounding. In order to improve efficiency, multiple…

Methodology · Statistics 2022-04-19 Baoluo Sun , Zhonghua Liu , Eric Tchetgen Tchetgen

Regression models usually tend to recover a noisy signal in the form of a combination of regressors, also called features in machine learning, themselves being the result of a learning process.The alignment of the prior covariance feature…

Statistical Mechanics · Physics 2023-01-25 Cyril Furtlehner

We consider the application of a popular penalised regression method, Ridge Regression, to data with very high dimensions and many more covariates than observations. Our motivation is the problem of out-of-sample prediction and the setting…

Applications · Statistics 2012-05-04 Erika Cule , Maria De Iorio

Ridge regression is a popular method for dense least squares regularization. In this work, ridge regression is studied in the context of VAR model estimation and inference. The implications of anisotropic penalization are discussed and a…

Methodology · Statistics 2024-06-21 Giovanni Ballarin

Multiple randomization designs (MRDs) are a class of experimental designs used to handle interference in two-sided marketplaces. We investigate regression adjustment strategies for estimating total, spillover, and direct effects in MRDs. We…

Methodology · Statistics 2026-03-23 Timothy Sudijono , Lihua Lei , Lorenzo Masoero , Suhas Vijaykumar , Guido Imbens , James McQueen

Machine learning models can capture and amplify biases present in data, leading to disparate test performance across social groups. To better understand, evaluate, and mitigate these biases, a deeper theoretical understanding of how model…

Machine Learning · Computer Science 2025-03-19 Arjun Subramonian , Samuel J. Bell , Levent Sagun , Elvis Dohmatob

Consider the problem of joint parameter estimation and prediction in a Markov random field: i.e., the model parameters are estimated on the basis of an initial set of data, and then the fitted model is used to perform prediction (e.g.,…

Machine Learning · Computer Science 2007-07-13 Martin J. Wainwright

Multireference alignment (MRA) problem is to estimate an underlying signal from a large number of noisy circularly-shifted observations. The existing methods are always proposed under the hypothesis of a single Gaussian noise. However, the…

Optimization and Control · Mathematics 2021-07-23 Cuicui Zhao , Jun Liu , Xinqi Gong

Regularized linear regression is central to machine learning, yet its high-dimensional behavior with informative priors remains poorly understood. We provide the first exact asymptotic characterization of training and test risks for maximum…

Machine Learning · Statistics 2026-01-28 Malik Tiomoko , Ekkehard Schnoor

The method of multivariable Mendelian randomization uses genetic variants to instrument multiple exposures, to estimate the effect that a given exposure has on an outcome conditional on all other exposures included in a linear model.…

Methodology · Statistics 2024-08-20 Ashish Patel , James Lane , Stephen Burgess

The presented work investigates a sparse Bayesian incremental automatic relevance determination (IARD) algorithm in the context of multipath parameter estimation in a super-resolution regime. The corresponding estimation problem is highly…

Applications · Statistics 2015-03-09 Dmitriy Shutin , Nicolas Schneckenburger

High dimensional error covariance matrices and their inverses are used to weight the contribution of observation and background information in data assimilation procedures. As observation error covariance matrices are often obtained by…

Optimization and Control · Mathematics 2019-10-02 Jemima M. Tabeart , Sarah L. Dance , Amos S. Lawless , Nancy K. Nichols , Joanne A. Waller

Traditional instrumental variable (IV) estimators face a fundamental constraint: they can only accommodate as many endogenous treatment variables as available instruments. This limitation becomes particularly challenging in settings where…

Machine Learning · Computer Science 2025-06-25 Shiangyi Lin , Hui Lan , Vasilis Syrgkanis

We study the ridge regression (L2 regularized least squares) problem and its dual, which is also a ridge regression problem. We observe that the optimality conditions describing the primal and dual optimal solutions can be formulated in…

Numerical Analysis · Mathematics 2018-01-22 Ademir Alves Riberio , Peter Richtárik

Modern computational models in supervised machine learning are often highly parameterized universal approximators. As such, the value of the parameters is unimportant, and only the out of sample performance is considered. On the other hand…

Computation · Statistics 2021-11-04 Matthew Dixon , Tyler Ward

In many areas of science, complex phenomena are modeled by stochastic parametric simulators, often featuring high-dimensional parameter spaces and intractable likelihoods. In this context, performing Bayesian inference can be challenging.…

Machine Learning · Computer Science 2021-11-10 François Rozet , Gilles Louppe