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Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs…

Quantitative Methods · Quantitative Biology 2021-01-27 John H. Lagergren , John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

In this work, we present the physics-informed neural network (PINN) model applied particularly to dynamic problems in solid mechanics. We focus on forward and inverse problems. Particularly, we show how a PINN model can be used efficiently…

Neural and Evolutionary Computing · Computer Science 2025-12-16 Vijay Kag , Venkatesh Gopinath

Physics Informed Neural Network (PINN) is a scientific computing framework used to solve both forward and inverse problems modeled by Partial Differential Equations (PDEs). This paper introduces IDRLnet, a Python toolbox for modeling and…

Machine Learning · Computer Science 2021-07-12 Wei Peng , Jun Zhang , Weien Zhou , Xiaoyu Zhao , Wen Yao , Xiaoqian Chen

This dissertation investigates physics-informed neural networks (PINNs) as candidate models for encoding governing equations, and assesses their performance on experimental data from two different systems. The first system is a simple…

Machine Learning · Computer Science 2024-01-09 Hamza Alsharif

Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

State estimation is the cornerstone of the power system control center since it provides the operating condition of the system in consecutive time intervals. This work investigates the application of physics-informed neural networks (PINNs)…

Machine Learning · Computer Science 2026-04-07 Solon Falas , Markos Asprou , Charalambos Konstantinou , Maria K. Michael

Physics-Informed Neural Networks (PINNs) integrate machine learning with differential equations to solve forward and inverse problems while ensuring that predictions adhere to physical laws. Physiologically based pharmacokinetic (PBPK)…

Physics-informed neural networks (PINNs) are a newly emerging research frontier in machine learning, which incorporate certain physical laws that govern a given data set, e.g., those described by partial differential equations (PDEs), into…

Neural and Evolutionary Computing · Computer Science 2023-07-11 Bo Wang , A. K. Qin , Sajjad Shafiei , Hussein Dia , Adriana-Simona Mihaita , Hanna Grzybowska

The placement of temperature sensitive and safety-critical components is crucial in the automotive industry. It is therefore inevitable, even at the design stage of new vehicles that these components are assessed for potential safety…

Machine Learning · Computer Science 2022-03-23 Philip Heger , Markus Full , Daniel Hilger , Norbert Hosters

In this paper, we present a novel methodology for automatic adaptive weighting of Bayesian Physics-Informed Neural Networks (BPINNs), and we demonstrate that this makes it possible to robustly address multi-objective and multi-scale…

Computational Physics · Physics 2023-08-09 Sarah Perez , Suryanarayana Maddu , Ivo F. Sbalzarini , Philippe Poncet

Physics-informed neural networks (PINNs) have emerged as a powerful paradigm for solving partial differential equations (PDEs) by embedding physical laws directly into neural network training. However, solving high-fidelity PDEs remains…

Machine Learning · Computer Science 2026-02-03 Olaf Yunus Laitinen Imanov

Physics-Informed Neural Networks (PINNs) have emerged as a promising computational framework for solving differential equations by integrating deep learning with physical constraints. However, their application in gas turbines is still in…

Computational Engineering, Finance, and Science · Computer Science 2025-06-25 Afila Ajithkumar Sophiya , Sepehr Maleki , Giuseppe Bruni , Senthil K. Krishnababu

Physics-informed neural networks (PINNs) have emerged as a promising approach to solving partial differential equations (PDEs) using neural networks, particularly in data-scarce scenarios, due to their unsupervised training capability.…

Machine Learning · Computer Science 2025-03-25 Edgar Torres , Jonathan Schiefer , Mathias Niepert

This paper presents a physics-informed neural network (PINN) approach for monitoring the health of diesel engines. The aim is to evaluate the engine dynamics, identify unknown parameters in a "mean value" model, and anticipate maintenance…

Machine Learning · Computer Science 2023-08-29 Kamaljyoti Nath , Xuhui Meng , Daniel J Smith , George Em Karniadakis

Approximating solutions to partial differential equations (PDEs) is fundamental for the modeling of dynamical systems in science and engineering. Physics-informed neural networks (PINNs) are a recent machine learning-based approach, for…

Physics-Informed Neural Networks (PINNs) are a class of deep neural networks that are trained, using automatic differentiation, to compute the response of systems governed by partial differential equations (PDEs). The training of PINNs is…

Machine Learning · Computer Science 2021-04-27 Mohammad Amin Nabian , Rini Jasmine Gladstone , Hadi Meidani

We apply Physics-Informed Neural Networks (PINNs) for solving identification problems of nonhomogeneous materials. We focus on the problem with a background in elasticity imaging, where one seeks to identify the nonhomogeneous mechanical…

Machine Learning · Computer Science 2020-09-11 Enrui Zhang , Minglang Yin , George Em Karniadakis

Physics-informed neural networks (PINNs) are neural networks that embed the laws of dynamical systems modeled by differential equations into their loss function as constraints. In this work, we present a PINN framework applied to oncology.…

Machine Learning · Computer Science 2025-10-16 Kayode Olumoyin , Katarzyna Rejniak

Forecasting temporal processes such as virus spreading in epidemics often requires more than just observed time-series data, especially at the beginning of a wave when data is limited. Traditional methods employ mechanistic models like the…

Artificial Intelligence · Computer Science 2024-11-12 Thang Nguyen , Dung Nguyen , Kha Pham , Truyen Tran

Time-domain simulations are crucial for ensuring power system stability and avoiding critical scenarios that could lead to blackouts. The next-generation power systems require a significant increase in the computational cost and complexity…

Systems and Control · Electrical Eng. & Systems 2025-06-26 Ignasi Ventura Nadal , Jochen Stiasny , Spyros Chatzivasileiadis