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In this work, we develop an adaptive, multivariate partitioning algorithm for solving mixed-integer nonlinear programs (MINLP) with multi-linear terms to global optimality. This iterative algorithm primarily exploits the advantages of…

Optimization and Control · Mathematics 2019-02-05 Harsha Nagarajan , Mowen Lu , Site Wang , Russell Bent , Kaarthik Sundar

We study the complexity of cutting planes and branching schemes from a theoretical point of view. We give some rigorous underpinnings to the empirically observed phenomenon that combining cutting planes and branching into a branch-and-cut…

Optimization and Control · Mathematics 2021-05-20 Amitabh Basu , Michele Conforti , Marco Di Summa , Hongyi Jiang

The use of Mixed-Integer Linear Programming (MILP) models to represent neural networks with Rectified Linear Unit (ReLU) activations has become increasingly widespread in the last decade. This has enabled the use of MILP technology to…

Optimization and Control · Mathematics 2024-02-01 Fabian Badilla , Marcos Goycoolea , Gonzalo Muñoz , Thiago Serra

This paper addresses a mixed integer programming (MIP) formulation for the multi-item uncapacitated lot-sizing problem that is inspired from the trailer manufacturer. The proposed MIP model has been utilized to find out the optimum order…

Optimization and Control · Mathematics 2012-06-01 Maryam Mohammadi , Masine Md. Tap

Decision trees are highly interpretable models for solving classification problems in machine learning (ML). The standard ML algorithms for training decision trees are fast but generate suboptimal trees in terms of accuracy. Other discrete…

Machine Learning · Computer Science 2024-01-24 Krunal Kishor Patel , Guy Desaulniers , Andrea Lodi

We study computational aspects of a key problem in robust statistics -- the penalized least trimmed squares (LTS) regression problem, a robust estimator that mitigates the influence of outliers in data by capping residuals with large…

Optimization and Control · Mathematics 2026-04-15 Xiang Meng , Andrés Gómez , Rahul Mazumder

Solving Constraint Optimization Problems (COPs) can be dramatically simplified by boundary estimation, that is, providing tight boundaries of cost functions. By feeding a supervised Machine Learning (ML) model with data composed of known…

Artificial Intelligence · Computer Science 2021-11-08 Helge Spieker , Arnaud Gotlieb

Machine learning interatomic potentials (MLIPs) have proven to be wildly useful for molecular dynamics simulations, powering countless drug and materials discovery applications. However, MLIPs face two primary bottlenecks preventing them…

Machine Learning · Computer Science 2026-01-30 Kevin Han , Haolin Cong , Bowen Deng , Amir Barati Farimani

Recent advances in mathematical programming have made Mixed Integer Optimization a competitive alternative to popular regularization methods for selecting features in regression problems. The approach exhibits unquestionable foundational…

Methodology · Statistics 2019-10-01 Ana Kenney , Francesca Chiaromonte , Giovanni Felici

In this paper, we propose novel mixed-integer linear programming (MIP) formulations to model decision problems posed as influence diagrams. We also present a novel heuristic that can be employed to warm start the MIP solver, as well as…

Optimization and Control · Mathematics 2026-01-21 Helmi Hankimaa , Olli Herrala , Fabricio Oliveira , Jaan Tollander de Balsch

Mixed Integer Linear Programs (MILPs) are highly flexible and powerful tools for modeling and solving complex real-world combinatorial optimization problems. Recently, machine learning (ML)-guided approaches have demonstrated significant…

Artificial Intelligence · Computer Science 2025-06-13 Junyang Cai , Taoan Huang , Bistra Dilkina

Mixed-integer programming (MIP) research is both mathematically sophisticated and engineering-intensive: testing an algorithmic hypothesis within a branch-and-cut solver requires substantial implementation, debugging, tuning, and…

Artificial Intelligence · Computer Science 2026-05-12 Liding Xu , Yugeng Zhou , Sebastian Pokutta

The ability of machine learning (ML) algorithms to generalize well to unseen data has been studied through the lens of information theory, by bounding the generalization error with the input-output mutual information (MI), i.e., the MI…

Machine Learning · Statistics 2024-06-07 Kimia Nadjahi , Kristjan Greenewald , Rickard Brüel Gabrielsson , Justin Solomon

In this paper, we describe a comprehensive algorithmic framework for solving mixed integer bilevel linear optimization problems (MIBLPs) using a generalized branch-and-cut approach. The framework presented merges features from existing…

Optimization and Control · Mathematics 2021-04-20 Sahar Tahernejad , Ted K. Ralphs , Scott T. DeNegre

It is well-known that by adding integrality constraints to the semidefinite programming (SDP) relaxation of the max-cut problem, the resulting integer semidefinite program is an exact formulation of the problem. In this paper we show…

Optimization and Control · Mathematics 2023-11-09 Frank de Meijer , Renata Sotirov

Training machine learning (ML) algorithms is a computationally intensive process, which is frequently memory-bound due to repeatedly accessing large training datasets. As a result, processor-centric systems (e.g., CPU, GPU) suffer from…

Hardware Architecture · Computer Science 2023-09-07 Juan Gómez-Luna , Yuxin Guo , Sylvan Brocard , Julien Legriel , Remy Cimadomo , Geraldo F. Oliveira , Gagandeep Singh , Onur Mutlu

Decision trees are a popular machine learning model which are traditionally trained by heuristic methods. Massive improvements in computing power and optimisation techniques has led to renewed interest in learning globally optimal decision…

Optimization and Control · Mathematics 2025-11-25 Mitchell Keegan , Michael Forbes , Paul Corry , Mahdi Abolghasemi

Intelligent motion planning is one of the core components in automated vehicles, which has received extensive interests. Traditional motion planning methods suffer from several drawbacks in terms of optimality, efficiency and generalization…

Robotics · Computer Science 2020-05-12 Chenyang Xi , Tianyu Shi , Yuankai Wu , Lijun Sun

Cutting-plane methods are well-studied localization(and optimization) algorithms. We show that they provide a natural framework to perform machinelearning ---and not just to solve optimization problems posed by machinelearning--- in…

Machine Learning · Computer Science 2015-08-13 Liva Ralaivola , Ugo Louche

There has been a recent interest in cutting planes generated from two or more rows of the optimal simplex tableau. One can construct examples of integer programs for which a single cutting plane generated from two rows dominates the entire…

Optimization and Control · Mathematics 2017-01-25 Amitabh Basu , Pierre Bonami , Gerard Cornuejols , Francois Margot