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Background: Multiple medical and non-medical stressors, along with the complicity of their exposure pathways, have posted significant challenges to the epidemiological interpretation of the non-communicable diseases, including…

Applications · Statistics 2025-03-07 Jiangling Liu , Ya Liu , Banyun Zheng , Longjian Liu , Heqing Shen

Cardiovascular diseases (CVD) remain a leading health concern and contribute significantly to global mortality rates. While clinical advancements have led to a decline in CVD mortality, accurately identifying individuals who could benefit…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Minfeng Xu , Chen-Chen Fan , Yan-Jie Zhou , Wenchao Guo , Pan Liu , Jing Qi , Le Lu , Hanqing Chao , Kunlun He

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

Cardiovascular disease (CVD) remains the leading global cause of mortality, yet current risk stratification methods often fail to detect early, subclinical changes. Previous studies have generally not integrated retinal microvasculature…

Computer Vision and Pattern Recognition · Computer Science 2025-07-18 Inamullah , Ernesto Elias Vidal Rosas , Imran Razzak , Shoaib Jameel

In this work, a novel approach is proposed for joint analysis of high dimensional time-resolved cardiac motion features obtained from segmented cardiac MRI and low dimensional clinical risk factors to improve survival prediction in heart…

Quantitative Methods · Quantitative Biology 2019-10-09 Shihao Jin , Nicolò Savioli , Antonio de Marvao , Timothy JW Dawes , Axel Gandy , Daniel Rueckert , Declan P O'Regan

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Complication risk profiling is a key challenge in the healthcare domain due to the complex interaction between heterogeneous entities (e.g., visit, disease, medication) in clinical data. With the availability of real-world clinical data…

Machine Learning · Computer Science 2021-09-28 Thai-Hoang Pham , Changchang Yin , Laxmi Mehta , Xueru Zhang , Ping Zhang

The COVID-19 pandemic has caused substantial damage to global health. Even though three years have passed, the world continues to struggle with the virus. Concerns are growing about the impact of COVID-19 on the mental health of infected…

Computation and Language · Computer Science 2023-06-14 Jiageng Wu , Xian Wu , Yining Hua , Shixu Lin , Yefeng Zheng , Jie Yang

Cardiovascular diseases (CVDs) are notably prevalent among patients with obstructive sleep apnea (OSA), posing unique challenges in predicting CVD progression due to the intricate interactions of comorbidities. Traditional models typically…

Applications · Statistics 2024-07-02 Duy Nguyen , Ca Hoang , Phat K. Huynh , Tien Truong , Dang Nguyen , Abhay Sharma , Trung Q. Le

The comorbidities of hypertension impose a heavy burden on patients and society. Early identification is necessary to prompt intervention, but it remains a challenging task. This study aims to address this challenge by combining joint graph…

Machine Learning · Computer Science 2025-06-13 Leming Zhou , Zuo Wang , Zhixuan Duan

Cardiac indices estimation is of great importance during identification and diagnosis of cardiac disease in clinical routine. However, estimation of multitype cardiac indices with consistently reliable and high accuracy is still a great…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Wufeng Xue , Ali Islam , Mousumi Bhaduri , Shuo Li

In this paper, we characterize major depression (MD) as a complex dynamical system in which symptoms (e.g., insomnia and fatigue) are directly connected to one another in a network structure. We hypothesize that individuals can be…

We aim to comprehensively identify typical life-spanning trajectories and critical events that impact patients' hospital utilization and mortality. We use a unique dataset containing 44 million records of almost all inpatient stays from…

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman

On the increase of major depressive disorders (MDD), many researchers paid attention to their recognition and treatment. Existing MDD recognition algorithms always use a single time-frequency domain method method, but the single…

Neurons and Cognition · Quantitative Biology 2021-11-03 Xiaofang Sun , Xiangwei Zheng , Yonghui Xu , Lizhen Cui , Bin Hu

Cerebrovascular diseases (CVD) can lead to stroke and dementia. Stroke is the second leading cause of death world wide and dementia incidence is increasing by the year. There are several markers of CVD that are visible on brain imaging,…

Despite the abundance of bipartite networked systems, their organizing principles are less studied, compared to unipartite networks. Bipartite networks are often analyzed after projecting them onto one of the two sets of nodes. As a result…

Physics and Society · Physics 2017-03-10 Maksim Kitsak , Fragkiskos Papadopoulos , Dmitri Krioukov

Comorbid diseases co-occur and progress via complex temporal patterns that vary among individuals. In electronic health records we can observe the different diseases a patient has, but can only infer the temporal relationship between each…

Machine Learning · Computer Science 2020-01-22 Zhaozhi Qian , Ahmed M. Alaa , Alexis Bellot , Jem Rashbass , Mihaela van der Schaar
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