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The mechanical effects of membrane compositional inhomogeneities are analyzed in a process analogous of neck formation in cellular membranes. We cast on the Canham-Helfrich model of fluid membranes with both the spontaneous curvature and…
For addressing optimisation tasks on finite dimensional quantum systems, we give a comprehensive account of the foundations of gradient flows on Riemannian manifolds including new developments: we extend former results from Lie groups such…
The dynamical phase-space of axisymmetric Canham-Helfrich (CH) cells is constructed from a Hamiltonian field recapitulating membrane curvature-elasticity and systemic restrictions. Guiding principles are reparametrization to convert a…
This chapter describes how gradient flows and nonlinear power methods in Banach spaces can be used to solve nonlinear eigenvector-dependent eigenvalue problems, and how convergence of (discretized) approximations can be verified. We review…
Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…
We theoretically study the elastic deformation of a fluid membrane induced by an adhering spherical colloidal particle within the framework of a Helfrich energy. Based on a full optimization of the membrane shape we find a continuous…
We develop new variational principles to study stability and equilibrium of axisymmetric flows. We show that there is an infinite number of steady state solutions. We show that these steady states maximize a (non-universal) $H$-function. We…
The Helfrich bending energy plays an important role in providing a mechanism for the conformation of a lipid vesicle in theoretical biophysics, which is governed by the principle of energy minimization over configurations of appropriate…
We develop the geometric description of submanifolds in Newton--Cartan spacetime. This provides the necessary starting point for a covariant spacetime formulation of Galilean-invariant hydrodynamics on curved surfaces. We argue that this is…
Classical density-functional theory provides an efficient alternative to molecular dynamics simulations for understanding the equilibrium properties of inhomogeneous fluids. However, application of density-functional theory to multi-site…
We investigate the gradient flow of the $L^2$ norm of the Riemannian curvature on surfaces. We show long time existence with arbitrary initial data, and exponential convergence of the volume normalized flow to a constant scalar curvature…
This paper tackles the approximation of surface diffusion flow using a Cahn--Hilliard-type model. We introduce and analyze a new second order variational phase field model which associates the classical Cahn--Hilliard energy with two…
We study topology optimization governed by the incompressible Navier-Stokes flows using a phase field model. Novel stabilized semi-implicit schemes for the gradient flows of Allen-Cahn and Cahn-Hilliard types are proposed for solving the…
Steady fluid flows have very special topology. In this paper we describe necessary and sufficient conditions on the vorticity function of a 2D ideal flow on a surface with or without boundary, for which there exists a steady flow among…
Many large-scale and distributed optimization problems can be brought into a composite form in which the objective function is given by the sum of a smooth term and a nonsmooth regularizer. Such problems can be solved via a proximal…
Correctly formulated continuum models for lipid-bilayer membranes present a significant challenge to computational mechanics. In particular, the mid-surface behavior is that of a 2-dimensional fluid, while the membrane resists bending much…
Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to…
Recent theoretical advances in elasticity of membranes following Helfrich's famous spontaneous curvature model are summarized in this review. The governing equations describing equilibrium configurations of lipid vesicles, lipid membranes…
We consider rotating equilibrium states of fluid deformable surfaces. These states are characterized by a force balance between centrifugal and bending forces, involve surface Killing vector fields and are independent on the surface…
Many cellular organelles are membrane-bound structures with complex membrane composition and shape. Their shapes have been observed to depend on the metabolic state of the organelle, and the mechanisms that couple biochemical pathways and…