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Real-life medical data is often multimodal and incomplete, fueling the growing need for advanced deep learning models capable of integrating them efficiently. The use of diverse modalities, including histopathology slides, MRI, and genetic…

Artificial Intelligence · Computer Science 2024-10-02 Lucas Robinet , Ahmad Berjaoui , Ziad Kheil , Elizabeth Cohen-Jonathan Moyal

Causal representation learning (CRL) models aim to transform high-dimensional data into a latent space, enabling interventions to generate counterfactual samples or modify existing data based on the causal relationships among latent…

Machine Learning · Computer Science 2026-03-19 Alireza Sadeghi , Wael AbdAlmageed

In medical image segmentation, heterogeneous privacy policies across institutions often make joint training on pooled datasets infeasible, motivating continual image segmentation-learning from data streams without catastrophic forgetting.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Jiayi Wang , Wei Dai , Haoyu Wang , Sihan Yang , Haixia Bi , Jian Sun

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

High dimensional data analysis for exploration and discovery includes three fundamental tasks: dimensionality reduction, clustering, and visualization. When the three associated tasks are done separately, as is often the case thus far,…

Machine Learning · Computer Science 2020-12-02 Stan Z. Li , Lirong Wu , Zelin Zang

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

Multi-view multi-label learning frequently suffers from simultaneous feature absence and incomplete annotations, due to challenges in data acquisition and cost-intensive supervision. To tackle the complex yet highly practical problem while…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Quanjiang Li , Zhiming Liu , Tianxiang Xu , Tingjin Luo , Chenping Hou

Causal representation learning (CRL) enhances machine learning models' robustness and generalizability by learning structural causal models associated with data-generating processes. We focus on a family of CRL methods that uses contrastive…

Machine Learning · Statistics 2025-03-17 Xiusi Li , Sékou-Oumar Kaba , Siamak Ravanbakhsh

Causal Representation Learning (CRL) aims to uncover the data-generating process and identify the underlying causal variables and relations, whose evaluation remains inherently challenging due to the requirement of known ground-truth causal…

Machine Learning · Computer Science 2025-10-20 Guangyi Chen , Yunlong Deng , Peiyuan Zhu , Yan Li , Yifan Shen , Zijian Li , Kun Zhang

Building robust and real-time classifiers with diverse datasets are one of the most significant challenges to deep learning researchers. It is because there is a considerable gap between a model built with training (seen) data and real…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Mayanka Chandrashekar , Yugyung Lee

Despite strong zero-shot performance, SAM is unreliable under domain shift due to Mask-level Confidence Confusion (MCC), where a single IoU-based mask score fails to reflect pixel-wise reliability near boundaries. Motivated by the contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Hongyou Zhou , Marc Toussaint , Ling Shao , Zihan Ye

Convolutional networks (ConvNets) have achieved great successes in various challenging vision tasks. However, the performance of ConvNets would degrade when encountering the domain shift. The domain adaptation is more significant while…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Qi Dou , Cheng Ouyang , Cheng Chen , Hao Chen , Pheng-Ann Heng

Recent advances in multi-instance learning (MIL) have witnessed impressive performance in whole slide image (WSI) analysis. However, the inherent sparsity of tumors and their morphological diversity lead to obvious heterogeneity across…

Image and Video Processing · Electrical Eng. & Systems 2026-02-25 Tingting Zheng , Hongxun Yao , Kui Jiang , Sicheng Zhao , Yi Xiao

Domain Adaptation (DA) is crucial for robust deployment of medical image segmentation models when applied to new clinical centers with significant domain shifts. Source-Free Domain Adaptation (SFDA) is appealing as it can deal with privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Xinya Liu , Jianghao Wu , Tao Lu , Shaoting Zhang , Guotai Wang

This paper proposes a novel pixel-level distribution regularization scheme (DRSL) for self-supervised domain adaptation of semantic segmentation. In a typical setting, the classification loss forces the semantic segmentation model to…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Javed Iqbal , Hamza Rawal , Rehan Hafiz , Yu-Tseh Chi , Mohsen Ali

The recently introduced Segment Anything Model (SAM) combines a clever architecture and large quantities of training data to obtain remarkable image segmentation capabilities. However, it fails to reproduce such results for…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Tal Shaharabany , Aviad Dahan , Raja Giryes , Lior Wolf

Causal representation learning seeks to uncover causal relationships among high-level latent variables from low-level, entangled, and noisy observations. Existing approaches often either rely on deep neural networks, which lack…

Methodology · Statistics 2026-03-27 Wenjin Zhang , Yixin Wang , Yuqi Gu

Predicting the impact of genomic and drug perturbations in cellular function is crucial for understanding gene functions and drug effects, ultimately leading to improved therapies. To this end, Causal Representation Learning (CRL)…

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Recently many multi-label image recognition (MLR) works have made significant progress by introducing pre-trained object detection models to generate lots of proposals or utilizing statistical label co-occurrence enhance the correlation…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Tao Pu , Mingzhan Sun , Hefeng Wu , Tianshui Chen , Ling Tian , Liang Lin