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We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Large Language Models (LLMs) are increasingly being integrated into various medical fields, including mental health support systems. However, there is a gap in research regarding the effectiveness of LLMs in non-English mental health…

Computation and Language · Computer Science 2026-02-10 Konstantinos Skianis , John Pavlopoulos , A. Seza Doğruöz

Large Language Models (LLMs) have become a key topic in AI and NLP, transforming sectors like healthcare, finance, education, and marketing by improving customer service, automating tasks, providing insights, improving diagnostics, and…

Artificial Intelligence · Computer Science 2025-12-05 Vignesh Kumar Kembu , Pierandrea Morandini , Marta Bianca Maria Ranzini , Antonino Nocera

Emotion estimation in music listening is confronting challenges to capture the emotion variation of listeners. Recent years have witnessed attempts to exploit multimodality fusing information from musical contents and physiological signals…

Artificial Intelligence · Computer Science 2016-12-01 Nattapong Thammasan , Ken-ichi Fukui , Masayuki Numao

Multimodal large language models (MLLMs) enhance the capabilities of standard large language models by integrating and processing data from multiple modalities, including text, vision, audio, video, and 3D environments. Data plays a pivotal…

Artificial Intelligence · Computer Science 2024-07-19 Tianyi Bai , Hao Liang , Binwang Wan , Yanran Xu , Xi Li , Shiyu Li , Ling Yang , Bozhou Li , Yifan Wang , Bin Cui , Ping Huang , Jiulong Shan , Conghui He , Binhang Yuan , Wentao Zhang

This paper presents our approach to the first Multimodal Personality-Aware Depression Detection Challenge, focusing on multimodal depression detection using machine learning and deep learning models. We explore and compare the performance…

Computation and Language · Computer Science 2025-08-29 Javier Si Zhao Hong , Timothy Zoe Delaya , Sherwyn Chan Yin Kit , Pai Chet Ng , Xiaoxiao Miao

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Electrocardiograms (ECGs) are non-invasive diagnostic tools crucial for detecting cardiac arrhythmic diseases in clinical practice. While ECG Self-supervised Learning (eSSL) methods show promise in representation learning from unannotated…

Signal Processing · Electrical Eng. & Systems 2024-07-03 Che Liu , Zhongwei Wan , Cheng Ouyang , Anand Shah , Wenjia Bai , Rossella Arcucci

The integration of information across multiple modalities and across time is a promising way to enhance the emotion recognition performance of affective systems. Much previous work has focused on instantaneous emotion recognition. The 2018…

Image and Video Processing · Electrical Eng. & Systems 2018-05-07 Didan Deng , Yuqian Zhou , Jimin Pi , Bertram E. Shi

Depression is a prevalent mental health disorder that is difficult to detect early due to subjective symptom assessments. Recent advancements in large language models have offered efficient and cost-effective approaches for this objective.…

Computation and Language · Computer Science 2025-04-08 Longdi Xian , Jianzhang Ni , Mingzhu Wang

Background: Electronic Health Records (EHRs) contain rich information of patients' health history, which usually include both structured and unstructured data. There have been many studies focusing on distilling valuable information from…

Machine Learning · Computer Science 2021-11-10 Ziyi Liu , Jiaqi Zhang , Yongshuai Hou , Xinran Zhang , Ge Li , Yang Xiang

Compared to traditional sentiment analysis, which only considers text, multimodal sentiment analysis needs to consider emotional signals from multimodal sources simultaneously and is therefore more consistent with the way how humans process…

Computation and Language · Computer Science 2024-08-19 Hao Yang , Yanyan Zhao , Yang Wu , Shilong Wang , Tian Zheng , Hongbo Zhang , Zongyang Ma , Wanxiang Che , Bing Qin

Electroencephalography (EEG) is shown to be a valuable data source for evaluating subjects' mental states. However, the interpretation of multi-modal EEG signals is challenging, as they suffer from poor signal-to-noise-ratio, are highly…

Signal Processing · Electrical Eng. & Systems 2022-04-19 David Bethge , Philipp Hallgarten , Ozan Özdenizci , Ralf Mikut , Albrecht Schmidt , Tobias Grosse-Puppendahl

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

This study presents a systematic comparison of three approaches for the analysis of mental health text using large language models (LLMs): prompt engineering, retrieval augmented generation (RAG), and fine-tuning. Using LLaMA 3, we evaluate…

Computation and Language · Computer Science 2025-04-01 Arshia Kermani , Veronica Perez-Rosas , Vangelis Metsis

Multimodal large language models (MLLMs) are increasingly being applied in the medical field, particularly in medical imaging. However, developing MLLMs for ECG signals, which are crucial in clinical settings, has been a significant…

Computation and Language · Computer Science 2024-11-25 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Multimodal Emotion Recognition (MER) focuses on identifying and interpreting emotions from modality-compound inputs. Closely mirroring human cognitive processes in real-world environments, MER has drawn substantial attention from both…

Multimedia · Computer Science 2026-05-21 Hongrui Zhang , Daiqing Wu , Yangyang Li , Kuien Liu , Yuhui Wang , Yu Zhou , Sicheng Zhao

In the past five years, research has shifted from traditional Machine Learning (ML) and Deep Learning (DL) approaches to leveraging Large Language Models (LLMs) , including multimodality, for data augmentation to enhance generalization, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Ranjan Sapkota , Shaina Raza , Maged Shoman , Achyut Paudel , Manoj Karkee

Instruction-tuned large language models (LLMs) have demonstrated promising zero-shot generalization capabilities across various downstream tasks. Recent research has introduced multimodal capabilities to LLMs by integrating independently…

Computation and Language · Computer Science 2023-11-29 Utsav Garg , Erhan Bas