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In this study, we present a technique that spans multi-scale views (global scale -- meaning brain network-level and local scale -- examining each individual ROI that constitutes the network) applied to resting-state fMRI volumes. Deep…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Ammu R. , Debanjali Bhattacharya , Ameiy Acharya , Ninad Aithal , Neelam Sinha

Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Sophie Starck , Yadunandan Vivekanand Kini , Jessica Johanna Maria Ritter , Rickmer Braren , Daniel Rueckert , Tamara Mueller

This study introduces a new method of visualizing complex tree structured objects. The usefulness of this method is illustrated in the context of detecting unexpected features in a data set of very large trees. The major contribution is a…

Applications · Statistics 2012-02-14 Burcu Aydin , Gabor Pataki , Haonan Wang , Alim Ladha , Elizabeth Bullitt , J. S. Marron

The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A…

Neurons and Cognition · Quantitative Biology 2023-10-12 Lukas AW Gemein , Robin T Schirrmeister , Joschka Boedecker , Tonio Ball

Brain aging is a complex and dynamic process, leading to functional and structural changes in the brain. These changes could lead to the increased risk of neurodegenerative diseases and cognitive decline. Accurate brain-age estimation…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Saadat Behzadi , Danial Sharifrazi , Roohallah Alizadehsani , Mojtaba Lotfaliany , Mohammadreza Mohebbi

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

While utilizing machine learning models, one of the most crucial aspects is how bias and fairness affect model outcomes for diverse demographics. This becomes especially relevant in the context of machine learning for medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Mahsa Dibaji , Neha Gianchandani , Akhil Nair , Mansi Singhal , Roberto Souza , Mariana Bento

We present a unified statistical framework for characterizing community structure of brain functional networks that captures variation across individuals and evolution over time. Existing methods for community detection focus only on…

Machine Learning · Computer Science 2022-01-10 Chee-Ming Ting , S. Balqis Samdin , Meini Tang , Hernando Ombao

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. In this study, complexity specific image categorization across different visual datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Vamshi K. Kancharala , Debanjali Bhattacharya , Neelam Sinha

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

Algebraic Topology · Mathematics 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon

The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

Ageing impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in…

Neurons and Cognition · Quantitative Biology 2022-09-07 L. J. Fosque , A. Alipour , M. Zare , R. V. Williams-Garcia , J. M. Beggs , G. Ortiz

Bone age assessment gives us evidence to analyze the children growth status and the rejuvenation involved chronological and biological ages. All the previous works consider left-hand X-ray image of a child in their works. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Hai-Duong Nguyen , Soo-Hyung Kim

Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Xiangrui Li , Jasmine Hect , Moriah Thomason , Dongxiao Zhu

Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However…

Emerging Technologies · Computer Science 2013-01-03 Nivedita Daimiwal , M. Sundhararajan , Revati Shriram

Deep learning-based medical image segmentation has seen tremendous progress over the last decade, but there is still relatively little transfer into clinical practice. One of the main barriers is the challenge of domain generalisation,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Kate Čevora , Ben Glocker , Wenjia Bai

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

Methodology · Statistics 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Human brain networks can be characterized at different temporal or spatial scales given by the age of the subject or the spatial resolution of the neuroimaging method. Integration of data across scales can only be successful if the combined…

Diffusion MRI measures of the human brain provide key insight into microstructural variations across individuals and into the impact of central nervous system diseases and disorders. One approach to extract information from diffusion…

Medical Physics · Physics 2022-01-19 Qianqian Yang , David C. Reutens , Viktor Vegh

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

Genomics · Quantitative Biology 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak
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