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Deep learning techniques have become prominent in modern fault diagnosis for complex processes. In particular, convolutional neural networks (CNNs) have shown an appealing capacity to deal with multivariate time-series data by converting…
Age-related Macular Degeneration (AMD) is the predominant cause of blindness in developed countries, specially in elderly people. Moreover, its prevalence is increasing due to the global population ageing. In this scenario, early detection…
In the last two decades Computer Aided Diagnostics (CAD) systems were developed to help radiologists analyze screening mammograms. The benefits of current CAD technologies appear to be contradictory and they should be improved to be…
Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…
Diabetic retinopathy refers to the pathology of the retina induced by diabetes and is one of the leading causes of preventable blindness in the world. Early detection of diabetic retinopathy is critical to avoid vision problem through…
Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of…
Universal lesion detection (ULD) on computed tomography (CT) images is an important but underdeveloped problem. Recently, deep learning-based approaches have been proposed for ULD, aiming to learn representative features from annotated CT…
The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…
Computational drug discovery provides an efficient tool helping large scale lead molecules screening. One of the major tasks of lead discovery is identifying molecules with promising binding affinities towards a target, a protein in…
Diabetic retinopathy (DR) is a major cause of visual impairment, and effective treatment options depend heavily on timely and accurate diagnosis. Deep learning models have demonstrated great success identifying DR from retinal images.…
Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…
Residual network (ResNet) and densely connected network (DenseNet) have significantly improved the training efficiency and performance of deep convolutional neural networks (DCNNs) mainly for object classification tasks. In this paper, we…
Diabetic retinopathy (DR) is the result of a complication of diabetes affecting the retina. It can cause blindness, if left undiagnosed and untreated. An ophthalmologist performs the diagnosis by screening each patient and analyzing the…
Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insufficient insulin production or impaired insulin utilization. One of its most severe complications is diabetic retinopathy (DR), a…
Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…
Automatic and accurate polyp segmentation plays an essential role in early colorectal cancer diagnosis. However, it has always been a challenging task due to 1) the diverse shape, size, brightness and other appearance characteristics of…
Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the…
In this study, we investigate what a practically useful approach is in order to achieve robust skin disease diagnosis. A direct approach is to target the ground truth diagnosis labels, while an alternative approach instead focuses on…
Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…
Automatic classification of pigmented, non-pigmented, and depigmented non-melanocytic skin lesions have garnered lots of attention in recent years. However, imaging variations in skin texture, lesion shape, depigmentation contrast, lighting…