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Related papers: Pan-cancer gene set discovery via scRNA-seq for op…

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Big Data works perfectly along with Deep learning to extract knowledge from a huge amount of data. However, this processing could take a lot of training time. Genomics is a Big Data science with high dimensionality. It relies on deep…

Neural and Evolutionary Computing · Computer Science 2024-05-28 Tasnim Assali , Zayneb Trabelsi Ayoub , Sofiane Ouni

Many machine learning models have been proposed to classify phenotypes from gene expression data. In addition to their good performance, these models can potentially provide some understanding of phenotypes by extracting explanations for…

Genomics · Quantitative Biology 2024-02-05 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Benjamin Audit , Pierre Borgnat , Jean-Michel Arbona

Breast Ultrasound plays a vital role in cancer diagnosis as a non-invasive approach with cost-effective. In recent years, with the development of deep learning, many CNN-based approaches have been widely researched in both tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Dat T. Chung , Minh-Anh Dang , Mai-Anh Vu , Minh T. Nguyen , Thanh-Huy Nguyen , Vinh Q. Dinh

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Deep learning has introduced several learning-based methods to recognize breast tumours and presents high applicability in breast cancer diagnostics. It has presented itself as a practical installment in Computer-Aided Diagnostic (CAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Timothy Kwong , Samaneh Mazaheri

Convolutional Neural Networks (CNN) have gained great success in many artificial intelligence tasks. However, finding a good set of hyperparameters for a CNN remains a challenging task. It usually takes an expert with deep knowledge, and…

Neural and Evolutionary Computing · Computer Science 2020-06-25 Xueli Xiao , Ming Yan , Sunitha Basodi , Chunyan Ji , Yi Pan

Endoscopy is widely used to diagnose gastric cancer and has a high diagnostic performance, but it must be performed by a physician, which limits the number of people who can be diagnosed. In contrast, gastric X-rays can be taken by…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Hideaki Okamoto , Quan Huu Cap , Takakiyo Nomura , Kazuhito Nabeshima , Jun Hashimoto , Hitoshi Iyatomi

Pancreatic cancer remains one of the leading causes of cancer-related mortality worldwide. Precise segmentation of pancreatic tumors from medical images is a bottleneck for effective clinical decision-making. However, achieving a high…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Linkai Peng , Zheyuan Zhang , Gorkem Durak , Frank H. Miller , Alpay Medetalibeyoglu , Michael B. Wallace , Ulas Bagci

Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Mirza Mumtaz Zahoor , Shahzad Ahmad Qureshi , Saddam Hussain Khan , Asifullah Khan

Pancreatic ductal adenocarcinoma (PDAC) presents a critical global health challenge, and early detection is crucial for improving the 5-year survival rate. Recent medical imaging and computational algorithm advances offer potential…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Yu Shi , Hannah Tang , Michael Baine , Michael A. Hollingsworth , Huijing Du , Dandan Zheng , Chi Zhang , Hongfeng Yu

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

In this research, we have two serum SELDI (surface-enhanced laser desorption and ionization) mass spectra (MS) datasets to be used to select features amongst them to identify proteomic cancerous serums from normal serums. Features selection…

Machine Learning · Computer Science 2021-05-06 Ahmed Farag Seddik , Hassan Mostafa Ahmed

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

The genomic profile underlying an individual tumor can be highly informative in the creation of a personalized cancer treatment strategy for a given patient; a practice known as precision oncology. This involves next generation sequencing…

We perform differential expression analysis of high-throughput sequencing count data under a Bayesian nonparametric framework, removing sophisticated ad-hoc pre-processing steps commonly required in existing algorithms. We propose to use…

Applications · Statistics 2017-05-04 Siamak Zamani Dadaneh , Xiaoning Qian , Mingyuan Zhou

The decreasing costs and increasing speed and accuracy of DNA sample collection, preparation, and sequencing has rapidly produced an enormous volume of genetic data. However, fast and accurate analysis of the samples remains a bottleneck.…

Quantitative Methods · Quantitative Biology 2017-04-13 Stephanie Dodson , Darrell O. Ricke , Jeremy Kepner , Nelson Chiu , Anna Shcherbina

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Objective: This paper proposes a deep learning model for breast cancer detection from reconstructed images of microwave imaging scan data and aims to improve the accuracy and efficiency of breast tumor detection, which could have a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-21 Gayathri Girish , Ponnathota Spandana , Badrish Vasu

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

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