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Variational autoencoder (VAE) estimates the posterior parameters (mean and variance) of latent variables corresponding to each input data. While it is used for many tasks, the transparency of the model is still an underlying issue. This…

Machine Learning · Statistics 2023-02-23 Akira Nakagawa , Keizo Kato , Taiji Suzuki

We combine conditional variational autoencoders (VAE) with adversarial censoring in order to learn invariant representations that are disentangled from nuisance/sensitive variations. In this method, an adversarial network attempts to…

Machine Learning · Computer Science 2018-05-22 Ye Wang , Toshiaki Koike-Akino , Deniz Erdogmus

Despite advances in deep probabilistic models, learning discrete latent representations remains challenging. This work introduces a novel method to improve inference in discrete Variational Autoencoders by reframing the inference problem…

Machine Learning · Computer Science 2025-06-11 María Martínez-García , Grace Villacrés , David Mitchell , Pablo M. Olmos

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

The instrumental variable (IV) approach is a widely used way to estimate the causal effects of a treatment on an outcome of interest from observational data with latent confounders. A standard IV is expected to be related to the treatment…

Machine Learning · Computer Science 2022-11-30 Debo Cheng , Ziqi Xu , Jiuyong Li , Lin Liu , Jixue Liu , Thuc Duy Le

The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

Machine Learning · Computer Science 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

Much research has been devoted to the problem of learning fair representations; however, they do not explicitly the relationship between latent representations. In many real-world applications, there may be causal relationships between…

Machine Learning · Computer Science 2023-12-19 Ziqi Xu , Jixue Liu , Debo Cheng , Jiuyong Li , Lin Liu , Ke Wang

Learning representations of underlying environmental dynamics from partial observations is a critical challenge in machine learning. In the context of Partially Observable Markov Decision Processes (POMDPs), state representations are often…

Machine Learning · Computer Science 2024-11-13 Chao Han , Debabrota Basu , Michael Mangan , Eleni Vasilaki , Aditya Gilra

This study advances the Variational Autoencoder (VAE) framework by addressing challenges in Independent Component Analysis (ICA) under both determined and underdetermined conditions, focusing on enhancing the independence and…

Machine Learning · Statistics 2025-06-10 Yuan-Hao Wei , Yan-Jie Sun

Counterfactual estimation over time is important in various applications, such as personalized medicine. However, time-dependent confounding bias in observational data still poses a significant challenge in achieving accurate and efficient…

Machine Learning · Computer Science 2026-03-13 Nghia D. Nguyen , Pablo Robles-Granda , Lav R. Varshney

The problem of fair classification can be mollified if we develop a method to remove the embedded sensitive information from the classification features. This line of separating the sensitive information is developed through the causal…

Machine Learning · Computer Science 2020-12-10 Hyemi Kim , Seungjae Shin , JoonHo Jang , Kyungwoo Song , Weonyoung Joo , Wanmo Kang , Il-Chul Moon

We would like to learn a representation of the data which decomposes an observation into factors of variation which we can independently control. Specifically, we want to use minimal supervision to learn a latent representation that…

Machine Learning · Computer Science 2017-05-25 Diane Bouchacourt , Ryota Tomioka , Sebastian Nowozin

Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route to understanding how perturbations reshape cellular…

Machine Learning · Computer Science 2026-05-26 Wenkang Jiang , Yuhang Liu , Erdun Gao , Ehsan Abbasnejad , Lina Yao , Javen Qinfeng Shi

Estimating the individual treatment effect (ITE) from observational data is meaningful and practical in healthcare. Existing work mainly relies on the strong ignorability assumption that no hidden confounders exist, which may lead to bias…

Methodology · Statistics 2020-12-16 Ruoqi Liu , Changchang Yin , Ping Zhang

Treatment effect estimation from observational data has attracted significant attention across various research fields. However, many widely used methods rely on the unconfoundedness assumption, which is often unrealistic due to the…

Machine Learning · Computer Science 2025-02-21 Di Fan , Renlei Jiang , Yunhao Wen , Chuanhou Gao

Variational autoencoders (VAEs) combine latent variables with amortized variational inference, whose optimization usually converges into a trivial local optimum termed posterior collapse, especially in text modeling. By tracking the…

Computation and Language · Computer Science 2020-04-21 Chen Wu , Prince Zizhuang Wang , William Yang Wang

Mining genuine mechanisms underlying the complex data generation process in real-world systems is a fundamental step in promoting interpretability of, and thus trust in, data-driven models. Therefore, we propose a variation-based cause…

Artificial Intelligence · Computer Science 2022-11-23 Mohamed Amine ben Salem , Karim Said Barsim , Bin Yang

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding…

Machine Learning · Computer Science 2024-05-28 Feng Xie , Zhengming Chen , Shanshan Luo , Wang Miao , Ruichu Cai , Zhi Geng

Controllable data generation aims to synthesize data by specifying values for target concepts. Achieving this reliably requires modeling the underlying generative factors and their relationships. In real-world scenarios, these factors…

Machine Learning · Computer Science 2025-11-21 Qilong Zhao , Shiyu Wang , Zeeshan Memon , Yang Qiao , Guangji Bai , Bo Pan , Zhaohui Qin , Liang Zhao

The increasing availability of electrocardiogram (ECG) data has motivated the use of data-driven models for automating various clinical tasks based on ECG data. The development of subject-specific models are limited by the cost and…

Machine Learning · Computer Science 2018-08-07 Prashnna K Gyawali , B. Milan Horacek , John L. Sapp , Linwei Wang