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Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…

Soft Condensed Matter · Physics 2025-08-27 Henry Alston , Raphael Voituriez , Thibault Bertrand

Cell motility underlies many biological processes, including cancer metastasis, bacterial infection, and evolutionary adaptation. We introduce a non-equilibrium single-cell motility model inspired by the generalized Langevin equation, which…

Biological Physics · Physics 2026-01-27 Anton Klimek , Prince V. Baruah , Prerna Sharma , Roland R. Netz

It is shown that the critical properties of a recently studied model for non-equilibrium wetting are robust if one extends the dynamic rules by single-particle diffusion on terraces of the wetting layer. Examining the behavior at the…

Statistical Mechanics · Physics 2016-08-16 S. Rössner , H. Hinrichsen

In thermodynamic equilibrium, the fluctuation-dissipation theorem links thermal fluctuations and dissipation. Biological systems, however, are driven out of equilibrium by internal processes that produce additional, active fluctuations.…

Soft Condensed Matter · Physics 2026-01-29 Ashot Matevosyan , Frank Jülicher , Ricard Alert

Recent experimental advances in ultrafast phenomena have triggered renewed interest in the dynamics of correlated quantum systems away from equilibrium. We review nonequilibrium dynamical mean-field theory studies of both the transient and…

Strongly Correlated Electrons · Physics 2020-05-25 Herbert F. Fotso , James K. Freericks

Biological membranes undergo noticeable thermal fluctuations at physiological temperatures. When two membranes approach each other, they hinder the out of plane fluctuations of the other. This hindrance leads to an entropic repulsive force…

Soft Condensed Matter · Physics 2021-04-27 Kosar Mozaffari , Fatemeh Ahmadpoor , Pradeep Sharma

The nonexponential relaxation and aging inherent to complex dynamics manifested in a wide variety of dissipative systems is analyzed through a model of diffusion in phase space in the presence of a nonconservative force. The action of this…

Statistical Mechanics · Physics 2009-11-11 A. Perez-Madrid

Non-local and non-convex energies represent fundamental interacting effects regulating the complex behavior of many systems in biophysics and materials science. We study one dimensional, prototypical schemes able to represent the behavior…

Statistical Mechanics · Physics 2022-12-08 Andrea Cannizzo , Luca Bellino , Giuseppe Florio , Giuseppe Puglisi , Stefano Giordano

We study nonequilibrium thermodynamics of complex information flows induced by interactions between multiple fluctuating systems. Characterizing nonequilibrium dynamics by causal networks (i.e., Bayesian networks), we obtain novel…

Statistical Mechanics · Physics 2013-11-07 Sosuke Ito , Takahiro Sagawa

Thermodynamic principles are often deceptively simple and yet surprisingly powerful. We show how a simple rule, such as the net flow of energy in and out of a moving atom under nonequilibrium steady state condition, can expose the…

Quantum Physics · Physics 2020-11-30 Daniel Reiche , Francesco Intravaia , Jen-Tsung Hsiang , Kurt Busch , Bei-Lok Hu

Long-range thermal fluctuations appear in fluids in nonequilibrium states leading to fluctuation-induced Casimir-like forces. Two distinct mechanisms have been identified for the origin of the long-range nonequilibrium fluctuations in…

Statistical Mechanics · Physics 2016-02-03 T. R. Kirkpatrick , J. M. Ortiz de Zárate , J. V. Sengers

We apply a recently developed model of cytoskeletal force generation to study a cell intrinsic contractility, as well as its response to external loading. The model is based on a non-equilibrium thermodynamic treatment of the…

Subcellular Processes · Quantitative Biology 2015-06-19 Mirko Maraldi , Clara Valero , Krishna Garikipati

We study the comparative importance of thermal to non-thermal fluctuations for membrane-based models in the linear regime. Our results, both in 1+1 and 2+1 dimensions, suggest that non-thermal fluctuations dominate thermal ones only when…

Statistical Mechanics · Physics 2011-09-28 Amit K. Chattopadhyay

The dynamics within active fluids, driven by internal activity of the self-propelled particles, is a subject of intense study in non-equilibrium physics. These systems have been explored using simulations, where the motion of a passive…

Biological Physics · Physics 2018-04-03 Saroj Kumar Nandi , Nir S. Gov

We present a theoretical investigation of thermal fluctuation statistics in a molecular motor. Energy transfer in the motor is described using a multidimensional discrete master equation with nearest-neighbor hopping. In this theory, energy…

Statistical Mechanics · Physics 2014-01-07 K. J. Challis , M. W. Jack

This work reports the results of the theoretical investigation of nonlinear dynamics and spiral wave breakup in a generalized two-variable model of cardiac action potential accounting for thermo-electric coupling and diffusion…

Tissues and Organs · Quantitative Biology 2018-11-07 A. Gizzi , A. Loppini , R. Ruiz-Baier , A. Ippolito , A. Camassa , A. La Camera , E. Emmi , L. Di Perna , V. Garofalo , C. Cherubini , S. Filippi

Coupling between chemical fuel consumption and phase separation can lead to condensation at a nonequilibrium steady state, resulting in phase behaviors that are not described by equilibrium thermodynamics. Theoretical models of such…

Soft Condensed Matter · Physics 2025-05-23 Yongick Cho , William M. Jacobs

The glass transition, extensively studied in dense fluids, polymers, or colloids, corresponds to a dramatic evolution of equilibrium transport coefficients upon a modest change of control parameter, like temperature or pressure. A similar…

Statistical Mechanics · Physics 2013-05-06 Ludovic Berthier , Jorge Kurchan

Living cells exhibit non-equilibrium dynamics emergent from the intricate interplay between molecular motor activity and its viscoelastic cytoskeletal matrix. The deviation from thermal equilibrium can be quantified through…

Biological Physics · Physics 2025-03-24 N Narinder , Elisabeth Fischer-Friedrich

In this work, we study in detail the distribution of stochastic forces generated by the molecular motors activity, in the actin cortex of pre-muscular cells. By combining active and passive rheology experiments, performed on the same…

Biological Physics · Physics 2019-12-10 P. Bohec , J. Tailleur , F. van Wijland , A. Richert , F. Gallet