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We introduce SPARse Fine-grained Contrastive Alignment (SPARC), a simple method for pretraining more fine-grained multimodal representations from image-text pairs. Given that multiple image patches often correspond to single words, we…

We introduce a novel masked graph autoencoder (MGAE) framework to perform effective learning on graph structure data. Taking insights from self-supervised learning, we randomly mask a large proportion of edges and try to reconstruct these…

Machine Learning · Computer Science 2022-01-10 Qiaoyu Tan , Ninghao Liu , Xiao Huang , Rui Chen , Soo-Hyun Choi , Xia Hu

Spatial transcriptomics (ST) enables transcriptome-wide profiling while preserving the spatial context of tissues, offering unprecedented opportunities to study tissue organization and cell-cell interactions in situ. Despite recent…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Wei Wang , Quoc-Toan Ly , Chong Yu , Jun Bai

Spatio-temporal prediction is crucial in numerous real-world applications, including traffic forecasting and crime prediction, which aim to improve public transportation and safety management. Many state-of-the-art models demonstrate the…

Machine Learning · Computer Science 2023-10-30 Jiabin Tang , Lianghao Xia , Jie Hu , Chao Huang

The recent advancement of spatial transcriptomics (ST) allows to characterize spatial gene expression within tissue for discovery research. However, current ST platforms suffer from low resolution, hindering in-depth understanding of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Xiaofei Wang , Xingxu Huang , Stephen J. Price , Chao Li

Conformal Autoencoders are a neural network architecture that imposes orthogonality conditions between the gradients of latent variables to obtain disentangled representations of data. In this work we show that orthogonality relations…

Machine Learning · Computer Science 2025-07-14 George A. Kevrekidis , Zan Ahmad , Mauro Maggioni , Soledad Villar , Yannis G. Kevrekidis

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

Hyperspectral satellite imagery offers sub-30 m views of Earth in hundreds of contiguous spectral bands, enabling fine-grained mapping of soils, crops, and land cover. While self-supervised Masked Autoencoders excel on RGB and low-band…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Tanjim Bin Faruk , Abdul Matin , Shrideep Pallickara , Sangmi Lee Pallickara

Graph clustering discovers groups or communities within networks. Deep learning methods such as autoencoders (AE) extract effective clustering and downstream representations but cannot incorporate rich structural information. While Graph…

Machine Learning · Computer Science 2022-04-28 Gayan K. Kulatilleke , Marius Portmann , Shekhar S. Chandra

Spatial transcriptomics (ST) technologies enable transcriptome-wide gene expression profiling while preserving spatial resolution, offering unprecedented opportunities to uncover complex spatial structures. Due to the ultra-high…

Applications · Statistics 2026-03-11 Changhu Wang , Qiyun Huang , Zihao Chen , Jin Liu , Ruibin Xi

Accurate cell type annotation is a crucial step in analyzing single-cell RNA sequencing (scRNA-seq) data, which provides valuable insights into cellular heterogeneity. However, due to the high dimensionality and prevalence of zero elements…

Machine Learning · Computer Science 2025-08-14 Huifa Li , Jie Fu , Xinlin Zhuang , Haolin Yang , Xinpeng Ling , Tong Cheng , Haochen xue , Imran Razzak , Zhili Chen

Self-supervised learning (SSL) methods such as masked language modeling have shown massive performance gains by pretraining transformer models for a variety of natural language processing tasks. The follow-up research adapted similar…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Gokul Karthik Kumar , Sahal Shaji Mullappilly , Abhishek Singh Gehlot

Medical image segmentation is critical for clinical diagnosis, treatment planning, and monitoring, yet segmentation models often struggle with uncertainties stemming from occlusions, ambiguous boundaries, and variations in imaging devices.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Xiao Ma , Yuhui Tao , Zetian Zhang , Yuhan Zhang , Xi Wang , Sheng Zhang , Zexuan Ji , Yizhe Zhang , Qiang Chen , Guang Yang

The goal of this work is to address two limitations in autoencoder-based models: latent space interpretability and compatibility with unstructured meshes. This is accomplished here with the development of a novel graph neural network (GNN)…

Machine Learning · Computer Science 2023-02-20 Shivam Barwey , Varun Shankar , Venkatasubramanian Viswanathan , Romit Maulik

Spatial Transcriptomics (ST) reveals the spatial distribution of gene expression in tissues, offering critical insights into biological processes and disease mechanisms. However, the high cost, limited coverage, and technical complexity of…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Yi Niu , Jiashuai Liu , Yingkang Zhan , Jiangbo Shi , Di Zhang , Marika Reinius , Ines Machado , Mireia Crispin-Ortuzar , Jialun Wu , Chen Li , Zeyu Gao

Graph embedding methods including traditional shallow models and deep Graph Neural Networks (GNNs) have led to promising applications in recommendation. Nevertheless, shallow models especially random-walk-based algorithms fail to adequately…

Information Retrieval · Computer Science 2022-08-04 Jiayi Zheng , Ling Yang , Heyuan Wang , Cheng Yang , Yinghong Li , Xiaowei Hu , Shenda Hong

Recently image-to-image translation has received increasing attention, which aims to map images in one domain to another specific one. Existing methods mainly solve this task via a deep generative model, and focus on exploring the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-24 Songyao Jiang , Zhiqiang Tao , Yun Fu

State-of-the-art deep learning methods have shown a remarkable capacity to model complex data domains, but struggle with geospatial data. In this paper, we introduce SpaceGAN, a novel generative model for geospatial domains that learns…

Machine Learning · Computer Science 2019-05-24 Konstantin Klemmer , Adriano Koshiyama , Sebastian Flennerhag

Markerless motion capture (MMC) is revolutionizing gait analysis in clinical settings by making it more accessible, raising the question of how to extract the most clinically meaningful information from gait data. In multiple fields ranging…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 R. James Cotton , J. D. Peiffer , Kunal Shah , Allison DeLillo , Anthony Cimorelli , Shawana Anarwala , Kayan Abdou , Tasos Karakostas

Spatial Transcriptomics (ST) provides spatially resolved gene expression profiles within intact tissue architecture, enabling molecular analysis in histological context. However, the high cost, limited throughput, and restricted data…

Machine Learning · Computer Science 2026-03-31 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou
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