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Parkinson's disease is a neurological condition that occurs in nearly 1% of the world's population. The disease is manifested by a drop in dopamine production, symptoms are cognitive and behavioural and include a wide range of personality…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Maria Frasca , Davide La Torre , Gabriella Pravettoni , Ilaria Cutica

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This…

This study introduces an explainable AI (XAI) framework for the detection of dyslexia through handwriting analysis, achieving an impressive test precision of 99.65%. The framework integrates transfer learning and transformer-based models,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Mahmoud Robaa , Mazen Balat , Rewaa Awaad , Esraa Omar , Salah A. Aly

Studies on schizophrenia assessments using deep learning typically treat it as a classification task to detect the presence or absence of the disorder, oversimplifying the condition and reducing its clinical applicability. This traditional…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-29 Gowtham Premananth , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Schizophrenia (SZ) is a severe brain disorder marked by diverse cognitive impairments, abnormalities in brain structure, function, and genetic factors. Its complex symptoms and overlap with other psychiatric conditions challenge traditional…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince D. Calhoun , Dong Hye Ye

Schizophrenia (SCZ), as a chronic and persistent disorder, exhibits working memory deficits across various stages of the disorder, yet the neural mechanisms underlying these deficits remain elusive with inconsistent neuroimaging findings.…

Neurons and Cognition · Quantitative Biology 2023-10-16 Yuhao Yao , Shufang Zhang , Boyao Wang , Gaofeng Zhao , Hong Deng , Ying Chen

Structural alterations have been thoroughly investigated in the brain during the early onset of schizophrenia (SCZ) with the development of neuroimaging methods. The objective of the paper is an efficient classification of SCZ in 2…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 P Supriya Patro , Tripti Goel , S A VaraPrasad , M Tanveer , R Murugan

We have reported nanometer-scale three-dimensional studies of brain networks of schizophrenia cases and found that their neurites are thin and tortuous compared to healthy controls. This suggests that connections between distal neurons are…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Ryuta Mizutani , Senta Noguchi , Rino Saiga , Yuichi Yamashita , Mitsuhiro Miyashita , Makoto Arai , Masanari Itokawa

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

Nowadays, due to tremendous improvements in high performance computing, it has become easier to train Neural Networks. We intend to take advantage of this situation and apply this technology in solving real world problems. There was a need…

Computer Vision and Pattern Recognition · Computer Science 2019-10-15 Gururaj Awate , Sunil Bangare , G Pradeepini , S Patil

In this study, we leverage a deep learning-based method for the automatic diagnosis of schizophrenia using EEG brain recordings. This approach utilizes generative data augmentation, a powerful technique that enhances the accuracy of the…

Machine Learning · Computer Science 2024-07-18 Mehrshad Saadatinia , Armin Salimi-Badr

Natural language processing tools are used to automatically detect disturbances in transcribed speech of schizophrenia inpatients who speak Hebrew. We measure topic mutation over time and show that controls maintain more cohesive speech…

Computation and Language · Computer Science 2019-04-18 Kfir Bar , Vered Zilberstein , Ido Ziv , Heli Baram , Nachum Dershowitz , Samuel Itzikowitz , Eiran Vadim Harel

Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, which work in a coordinated way. However, the vast majority of studies focus on the differential expression of one individual…

Genomics · Quantitative Biology 2019-08-22 Akram Yazdani , Raul Mendez-Giraldez , Michael R Kosorok , Panos Roussos

Handwriting is significantly affected by neurological disorders (ND) such as Parkinson's disease (PD) and Alzheimer's disease (AD). Prior works have analyzed handwriting tasks using feature-based approaches or computer-vision techniques,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Gabrielle Chavez , Laureano Moro-Velazquez , Ankur Butala , Najim Dehak , Thomas Thebaud

Schizophrenia and bipolar disorder are debilitating psychiatric illnesses that can be challenging to diagnose accurately. The similarities between the diseases make it difficult to differentiate between them using traditional diagnostic…

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

The hydrocephalus can be either an independent disease or a concomitant symptom of a number of pathologies, therefore representing an urgent issue in the present-day clinical practice. Deep Learning is an evolving technology and the part of…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Alexey Demyanchuk , Ekaterina Pushkina , Nikolay Russkikh , Dmitry Shtokalo , Sergey Mishinov

As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Usman Mahmood , Md Mahfuzur Rahman , Alex Fedorov , Zening Fu , Sergey Plis

Using kinematic properties of handwriting to support the diagnosis of neurodegenerative disease is a real challenge: non-invasive detection techniques combined with machine learning approaches promise big steps forward in this research…

Computation and Language · Computer Science 2024-01-08 Nicole Dalia Cilia , Claudio De Stefano , Francesco Fontanella , Sabato Marco Siniscalchi