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Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Sleep monitoring provides valuable insights into the general health of an individual and helps in the diagnostic of sleep-derived illnesses. Polysomnography, is considered the gold standard for such task. However, it is very unwieldy and…

Understanding and estimating driver trust and comfort are essential for the safety and widespread acceptance of autonomous vehicles. Existing works analyze user trust and comfort separately, with limited real-time assessment and…

Human-Computer Interaction · Computer Science 2025-08-26 Aditi Bhalla , Christian Hellert , Enkelejda Kasneci , Nastassja Becker

Objectives: This study examines human Photoplethysmogram (PPG) along with Electrocardiogram (ECG) signals to study cardiac autonomic imbalance in epileptic seizures. The significance and the prevalence of changes in PPG morphological…

Signal Processing · Electrical Eng. & Systems 2019-12-12 Seyede Mahya Safavi , Ninaz Valisharifabad , Robert Sabino , Hsinchung Chen , Ali HeydariGorji , Demi Tran , Jack Lin , Beth Lopour , Pai H. Chou

Simulation models often have parameters as input and return outputs to understand the behavior of complex systems. Calibration is the process of estimating the values of the parameters in a simulation model in light of observed data from…

Methodology · Statistics 2024-11-15 Özge Sürer

Background: A smartphone is a promising tool for daily cardiovascular measurement and mental stress monitoring. A smartphone camera-based PhotoPlethysmoGraphy (PPG) and a low-cost thermal camera can be used to create cheap, convenient and…

Medical Physics · Physics 2019-01-03 Youngjun Cho , Simon J. Julier , Nadia Bianchi-Berthouze

Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…

Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine in vivo mechanical parameters of valves limits the accuracy…

Quantitative Methods · Quantitative Biology 2025-07-09 Wensi Wu , Mitchell Daneker , Christian Herz , Hannah Dewey , Jeffrey A. Weiss , Alison M. Pouch , Lu Lu , Matthew A. Jolley

The use of mechanistic models in clinical studies is limited by the lack of multi-modal patients data representing different anatomical and physiological processes. For example, neuroimaging datasets do not provide a sufficient…

Machine Learning · Computer Science 2025-09-18 Jaume Banus , Maxime Sermesant , Oscar Camara , Marco Lorenzi

In vivo skin exhibits viscoelastic, hyper-elastic and non-linear characteristics. It is under a constant non-equibiaxial tension in its natural configuration and is reinforced with oriented collagen fibers, giving rise to anisotropic…

Biological Physics · Physics 2025-06-04 Matt Nagle , Susan Price , Antonia Trotta , Michel Destrade , Michael Fop , Aisling Ní Annaidh

The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in space and frictionless sliding of the myocardium.…

Computational Engineering, Finance, and Science · Computer Science 2018-12-11 Martin R. Pfaller , Julia M. Hörmann , Martina Weigl , Andreas Nagler , Radomir Chabiniok , Cristóbal Bertoglio , Wolfgang A. Wall

The mechanisms of infant development are far from understood. Learning about one's own body is likely a foundation for subsequent development. Here we look specifically at the problem of how spontaneous touches to the body in early infancy…

Robotics · Computer Science 2020-09-01 Filipe Gama , Maksym Shcherban , Matthias Rolf , Matej Hoffmann

This paper introduces a biomathematical model designed to describe the internal dynamics of dream formation and spontaneous cognitive processes. The model incorporates neurocognitive factors such as dissatisfaction, acceptance, forgetting,…

Neurons and Cognition · Quantitative Biology 2025-05-12 Shirmohammad Tavangari , Sajjad Janfaza , Zahra Shakarami , Aref Yelghi

Remote photoplethysmography (rPPG) offers a promising solution for non-contact driver monitoring by detecting subtle blood flow-induced facial color changes from video. However, motion artifacts in dynamic driving environments remain key…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Đorđe D. Nešković , Kristina Stojmenova Pečečnik , Jaka Sodnik , Nadica Miljković

Skin nerve activity (SKNA) derived from electrocardiogram (ECG) signals has been a promising non-invasive surrogate for accurate and effective assessment of the sympathetic nervous system (SNS). Typically, SKNA extraction requires a higher…

Signal Processing · Electrical Eng. & Systems 2025-08-04 Youngsun Kong , Farnoush Baghestani , I-Ping Chen , Ki Chon

Coronary heart disease (CAD) is one of the crucial reasons for cardiovascular mortality in middle-aged people worldwide. The most typical tool is angiography for diagnosing CAD. The challenges of CAD diagnosis using angiography are costly…

This work describes neural software applied in medicine and physiology to: investigate and diagnose immune deficiencies; diagnose and study allergic and pseudoallergic reactions; forecast emergence or aggravation of stagnant cardiac…

Quantitative Methods · Quantitative Biology 2007-05-23 A. N. Gorban , D. A. Rossiyev , M. G. Dorrer

Physiological sensors are gaining the attention of manufacturers and users. As denoted by devices such as smartwatches or the newly released Kinect 2 -- which can covertly measure heartbeats -- or by the popularity of smartphone apps that…

Human-Computer Interaction · Computer Science 2014-12-05 Jérémy Frey

Dynamic cerebral autoregulation, that is the transient response of cerebral blood flow to changes in arterial blood pressure, is currently assessed using a variety of different time series methods and data collection protocols. In the…

Quantitative Methods · Quantitative Biology 2017-05-16 Adam Mahdi , Dragana Nikolic , Anthony A. Birch , Mette S. Olufsen , Ronney B. Panerai , David M. Simpson , Stephen J. Payne

Statistical shape modeling (SSM) is a valuable and powerful tool to generate a detailed representation of complex anatomy that enables quantitative analysis and the comparison of shapes and their variations. SSM applies mathematics,…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Krithika Iyer , Alan Morris , Brian Zenger , Karthik Karanth , Benjamin A Orkild , Oleksandre Korshak , Shireen Elhabian