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This paper proposes a prototype of a new biofeedback training based on mathematical models of cardiovascular control. For this purpose we develop a low-cost device that is able to record and process arterial pulse wave via…

Neurons and Cognition · Quantitative Biology 2019-02-18 Michel Kana

This PhD thesis develops an integrated mathematical model for autonomic nervous system control on cardiovascular activity. The model extensively covers cardiovascular neural pathways including a wide range of afferent sensory neurons,…

Tissues and Organs · Quantitative Biology 2019-01-18 Michel Kana

We have advanced a point-process based framework for the regulation of heart beats by the autonomous nervous system and analyzed the model with and without feedback. The model without feedback was found amenable to several analytical…

Quantitative Methods · Quantitative Biology 2019-04-18 Bosco Emmanuel

We consider the problem of modeling cardiovascular responses to physical activity and sleep changes captured by wearable sensors in free living conditions. We use an attentional convolutional neural network to learn parsimonious signatures…

Machine Learning · Computer Science 2018-12-06 Haraldur T. Hallgrímsson , Filip Jankovic , Tim Althoff , Luca Foschini

Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progression, and clinical diagnosis. Although various in vivo methods have been developed to assess…

Medical Physics · Physics 2026-01-21 Yuxuan Jiang , Yanping Cao

Round-the-clock monitoring of human behavior and emotions is required in many healthcare applications which is very expensive but can be automated using machine learning (ML) and sensor technologies. Unfortunately, the lack of…

Signal Processing · Electrical Eng. & Systems 2021-02-17 Bonny Banerjee , Masoumeh Heidari Kapourchali , Murchana Baruah , Mousumi Deb , Kenneth Sakauye , Mette Olufsen

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Whole-body hemodynamics simulators, which model blood flow and pressure waveforms as functions of physiological parameters, are now essential tools for studying cardiovascular systems. However, solving the corresponding inverse problem of…

This article proposes a dynamical system modeling approach for the analysis of longitudinal data of self-regulated systems experiencing multiple excitations. The aim of such an approach is to focus on the evolution of a signal (e.g., heart…

The sympathetic nervous system (SNS) plays a central role in regulating the body's responses to stress and maintaining physiological stability. Its dysregulation is associated with a wide range of conditions, from cardiovascular disease to…

Artificial Intelligence · Computer Science 2025-09-10 Farnoush Baghestani , Jihye Moon , Youngsun Kong , Ki Chon

In this study, we develop a methodology for model reduction and selection informed by global sensitivity analysis (GSA) methods. We apply these techniques to a control model that takes systolic blood pressure and thoracic tissue pressure…

Quantitative Methods · Quantitative Biology 2021-05-17 E. Benjamin Randall , Nicholas Z. Randolph , Alen Alexanderian , Mette S. Olufsen

Despite the fact that only a small portion of muscles are affected in motion disease and disorders, medical therapies do not distinguish between healthy and unhealthy muscles. In this paper, a method is devised in order to calculate the…

Artificial Intelligence · Computer Science 2024-03-06 Sina Saadati , Mohammadreza Razzazi

Social anxiety disorder (SAD) is associated with heightened physiological arousal in social-evaluative contexts, but it remains unclear whether such autonomic reactivity extends to non-evaluative cognitive stressors. This study investigated…

Neurons and Cognition · Quantitative Biology 2025-07-23 Arya Adyasha , Anushka Sanjay Shelke , Haroon R Lone

Heart rate variability (HRV) is a practical and noninvasive measure of autonomic nervous system activity, which plays an essential role in cardiovascular health. However, using HRV to assess physiology status is challenging. Even in…

Signal Processing · Electrical Eng. & Systems 2022-03-24 Jiacheng Zhu , Gregory Darnell , Agni Kumar , Ding Zhao , Bo Li , Xuanlong Nguyen , Shirley You Ren

Recent research is revealing how cognitive processes are supported by a complex interplay between the brain and the rest of the body, which can be investigated by the analysis of physiological features such as breathing rhythms, heart rate,…

Quantitative Methods · Quantitative Biology 2023-03-10 Fernando E. Rosas , Diego Candia-Rivera , Andrea I Luppi , Yike Guo , Pedro A. M. Mediano

Recent work has shown that a person's sympathetic arousal can be estimated from facial videos alone using basic signal processing. This opens up new possibilities in the field of telehealth and stress management, providing a non-invasive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Björn Braun , Daniel McDuff , Tadas Baltrusaitis , Paul Streli , Max Moebus , Christian Holz

Continuous monitoring of non-invasive skin sympathetic nerve activity (SKNA) holds promise for understanding the sympathetic nervous system (SNS) dynamics in various physiological and pathological conditions. However, muscle noise artifacts…

Machine Learning · Computer Science 2024-10-30 Farnoush Baghestani , Mahdi Pirayesh Shirazi Nejad , Youngsun Kong , Ki H. Chon

The CVS is composed of numerous interacting and dynamically regulated physiological subsystems which each generate measurable periodic components such that the CVS can itself be presented as a system of weakly coupled oscillators. The…

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