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Robust control of complex engineered and biological systems hinges on the integration of feedforward and feedback mechanisms. This is exemplified in neural motor control, where feedforward muscle co-contraction complements sensory-driven…

Optimization and Control · Mathematics 2026-03-06 Bastien Berret , Frédéric Jean

A powerful approach for understanding neural population dynamics is to extract low-dimensional trajectories from population recordings using dimensionality reduction methods. Current approaches for dimensionality reduction on neural data…

Machine Learning · Statistics 2017-11-07 Marcel Nonnenmacher , Srinivas C. Turaga , Jakob H. Macke

Recent whole brain imaging experiments on $\textit{C. elegans}$ has revealed that the neural population dynamics encode motor commands and stereotyped transitions between behaviors on low dimensional manifolds. Efforts to characterize the…

Quantitative Methods · Quantitative Biology 2020-04-15 Charles Fieseler , Manuel Zimmer , J. Nathan Kutz

Robot navigation around humans can be a challenging problem since human movements are hard to predict. Stochastic model predictive control (MPC) can account for such uncertainties and approximately bound the probability of a collision to…

Robotics · Computer Science 2024-07-22 Yunfan Gao , Florian Messerer , Niels van Duijkeren , Moritz Diehl

Neurons in higher cortical areas, such as the prefrontal cortex, are known to be tuned to a variety of sensory and motor variables. The resulting diversity of neural tuning often obscures the represented information. Here we introduce a…

Neural manifolds are an attractive theoretical framework for characterizing the complex behaviors of neural populations. However, many of the tools for identifying these low-dimensional subspaces are correlational and provide limited…

Neurons and Cognition · Quantitative Biology 2025-08-12 Christof Fehrman , C. Daniel Meliza

In natural vision, feedback connections support versatile visual inference capabilities such as making sense of the occluded or noisy bottom-up sensory information or mediating pure top-down processes such as imagination. However, the…

Neurons and Cognition · Quantitative Biology 2023-11-01 Tahereh Toosi , Elias B. Issa

The study of population dynamics originated with early sociological works but has since extended into many fields, including biology, epidemiology, evolutionary game theory, and economics. Most studies on population dynamics focus on the…

Machine Learning · Computer Science 2024-06-07 Noah Golowich , Elad Hazan , Zhou Lu , Dhruv Rohatgi , Y. Jennifer Sun

Unknown nonlinear dynamics can limit the performance of model-based feedforward control. The aim of this paper is to develop a feedforward control framework for systems with unknown, typically nonlinear, dynamics. To address the unknown…

Systems and Control · Electrical Eng. & Systems 2023-03-31 Johan Kon , Dennis Bruijnen , Jeroen van de Wijdeven , Marcel Heertjes , Tom Oomen

How does our nervous system successfully acquire feedback control strategies in spite of a wide spectrum of response dynamics from different musculo-skeletal systems? The cerebellum is a crucial brain structure in enabling precise motor…

Neurons and Cognition · Quantitative Biology 2017-07-06 Ivan Herreros , Xerxes D. Arsiwalla , Cosimo Della Santina , Jordi-Ysard Puigbo , Antonio Bicchi , Paul Verschure

Modern AI systems are increasingly constrained not by model capacity but by the quality and diversity of their data. Despite growing emphasis on data-centric AI, most datasets are still gathered in an open-loop manner which accumulates…

Machine Learning · Computer Science 2025-11-11 Philipp Reis , Philipp Rigoll , Christian Steinhauser , Jacob Langner , Eric Sax

The study of density-dependent stochastic population processes is important from a historical perspective as well as from the perspective of a number of existing and emerging applications today. In more recent applications of these…

Optimization and Control · Mathematics 2017-09-26 Yingdong Lu , Mark Squillante , Chai Wah Wu

Model-based feedforward control improves tracking performance of motion systems, provided that the model describing the inverse dynamics is of sufficient accuracy. Model sets, such as neural networks (NNs) and physics-guided neural networks…

Systems and Control · Electrical Eng. & Systems 2022-04-04 Max Bolderman , Mircea Lazar , Hans Butler

Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

Machine Learning · Statistics 2014-10-14 Mijung Park , Jakob H. Macke

In this paper, we propose several approaches to learn the optimal population-dependent controls in order to solve mean field control problems (MFC). Such policies enable us to solve MFC problems with forms of common noises at a level of…

Optimization and Control · Mathematics 2023-11-21 Gokce Dayanikli , Mathieu Lauriere , Jiacheng Zhang

Neural Cellular Automata (NCAs) are a promising new approach to model self-organizing processes, with potential applications in life science. However, their deterministic nature limits their ability to capture the stochasticity of…

Artificial Intelligence · Computer Science 2025-06-26 Salvatore Milite , Giulio Caravagna , Andrea Sottoriva

Quantifying similarity between population spike patterns is essential for understanding how neural dynamics encode information. Traditional approaches, which combine kernel smoothing, PCA, and CCA, have limitations: smoothing kernel…

Neurons and Cognition · Quantitative Biology 2025-05-21 Xiang Zhang , Chenlin Xu , Zhouxiao Lu , Haonan Wang , Dong Song

Feedback control synthesis for large-scale particle systems is reviewed in the framework of model predictive control (MPC). The high-dimensional character of collective dynamics hampers the performance of traditional MPC algorithms based on…

Optimization and Control · Mathematics 2024-02-27 Giacomo Albi , Sara Bicego , Michael Herty , Yuyang Huang , Dante Kalise , Chiara Segala

Standard approaches to controlling dynamical systems involve biologically implausible steps such as backpropagation of errors or intermediate model-based system representations. Recent advances in machine learning have shown that…

Statistical Mechanics · Physics 2025-07-11 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

This paper develops a dynamical framework for adaptive coordination in systems of interacting agents referred to here as Feedback-Coupled Memory Systems (FCMS). Instead of framing coordination as equilibrium optimization or agent-centric…

Multiagent Systems · Computer Science 2026-03-31 Stefano Grassi
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