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Understanding causal heterogeneous treatment effects based on pretreatment covariates is a crucial aspect of empirical work. Building on Calonico, Cattaneo, Farrell, Palomba, and Titiunik (2025), this article discusses the software package…

Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents…

Methodology · Statistics 2025-10-31 Valerie Odeh-Couvertier , Gabriel Zayas-Caban , Brian Patterson , Amy Cochran

Probabilistic forecasting of multivariate time series is essential for various downstream tasks. Most existing approaches rely on the sequences being uniformly spaced and aligned across all variables. However, real-world multivariate time…

Machine Learning · Computer Science 2025-02-18 Yijun Li , Cheuk Hang Leung , Qi Wu

The Regression Discontinuity Design (RDD) is a quasi-experimental design that estimates the causal effect of a treatment when its assignment is defined by a threshold value for a continuous assignment variable. The RDD assumes that subjects…

Applications · Statistics 2020-03-27 Federico Ricciardi , Silvia Liverani , Gianluca Baio

Causal effect estimation for dynamic treatment regimes (DTRs) contributes to sequential decision making. However, censoring and time-dependent confounding under DTRs are challenging as the amount of observational data declines over time due…

Machine Learning · Statistics 2021-09-27 Adi Lin , Jie Lu , Junyu Xuan , Fujin Zhu , Guangquan Zhang

Deep learning time-series models are often used to make forecasts that inform downstream decisions. Since these decisions can differ from those in the training set, there is an implicit requirement that time-series models will generalize…

Machine Learning · Computer Science 2024-11-04 Thomas Crasson , Yacine Nabet , Mathias Lécuyer

We study variation in policing outcomes attributable to differential policing practices in New York City (NYC) using geographic regression discontinuity designs (GeoRDDs). By focusing on small geographic windows near police precinct…

Methodology · Statistics 2025-07-01 Emmett B. Kendall , Brenden Beck , Joseph Antonelli

Semicontinuous outcomes commonly arise in a wide variety of fields, such as insurance claims, healthcare expenditures, rainfall amounts, and alcohol consumption. Regression models, including Tobit, Tweedie, and two-part models, are widely…

Methodology · Statistics 2024-03-26 Lu Yang

Estimating community-specific mental health effects of local events is vital for public health policy. While forecasting mental health scores alone offers limited insights into the impact of events on community well-being,…

Machine Learning · Computer Science 2025-09-01 Siddharth Mangalik , Ojas Deshpande , Adithya V. Ganesan , Sean A. P. Clouston , H. Andrew Schwartz

Standard regression adjustment gives inconsistent estimates of causal effects when there are time-varying treatment effects and time-varying covariates. Loosely speaking, the issue is that some covariates are post-treatment variables…

Methodology · Statistics 2024-03-12 Stephen Bates , Edward Kennedy , Robert Tibshirani , Valerie Ventura , Larry Wasserman

A default assumption in reinforcement learning (RL) and optimal control is that observations arrive at discrete time points on a fixed clock cycle. Yet, many applications involve continuous-time systems where the time discretization, in…

Machine Learning · Computer Science 2024-01-17 Zichen Zhang , Johannes Kirschner , Junxi Zhang , Francesco Zanini , Alex Ayoub , Masood Dehghan , Dale Schuurmans

Repetitive Scenario Design (RSD) is a randomized approach to robust design based on iterating two phases: a standard scenario design phase that uses $N$ scenarios (design samples), followed by randomized feasibility phase that uses $N_o$…

Systems and Control · Computer Science 2016-02-12 Giuseppe C. Calafiore

The standard fuzzy regression discontinuity (FRD) estimator is a ratio of differences of local polynomial estimators. I show that this estimator does not possess any finite integer moments, regardless of local polynomial degree, kernel…

Econometrics · Economics 2026-04-30 Stuart Lane

Marginal structural models are a popular tool for investigating the effects of time-varying treatments, but they require an assumption of no unobserved confounders between the treatment and outcome. With observational data, this assumption…

Methodology · Statistics 2021-06-10 Matthew Blackwell , Soichiro Yamauchi

Regularized regression has become very popular nowadays, particularly on high-dimensional problems where the addition of a penalty term to the log-likelihood allows inference where traditional methods fail. A number of penalties have been…

Methodology · Statistics 2021-02-15 Hamed Haselimashhadi , Veronica Vinciotti

In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings…

Methodology · Statistics 2026-04-01 Eric Tong , Salvador V. Balkus

This handbook chapter gives an introduction to the sharp regression discontinuity design, covering identification, estimation, inference, and falsification methods.

Econometrics · Economics 2022-10-10 Matias D. Cattaneo , Rocio Titiunik , Gonzalo Vazquez-Bare

Difference-in-differences is one of the most used identification strategies in empirical work in economics. This chapter reviews a number of important, recent developments related to difference-in-differences. First, this chapter reviews…

Econometrics · Economics 2022-08-02 Brantly Callaway

In this work, we consider causal inference in various high-dimensional treatment settings, including for single multi-valued treatments and vector treatments with binary or continuous components, when the number of treatments can be…

Statistics Theory · Mathematics 2026-02-26 Patrick Kramer , Edward H. Kennedy , Isaac M. Opper

We present a novel approach for extrapolating causal effects away from the margin between treatment and non-treatment in sharp regression discontinuity designs with multiple covariates. Our methods apply both to settings in which treatment…

Econometrics · Economics 2025-07-02 Ben Deaner , Soonwoo Kwon
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