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The task of Multiple Sequence Alignment (MSA) is a constrained combinatorial optimization problem that is generally considered a complex computational problem. In this paper, we first present a binary encoding of MSA and devise a…

We introduce HAML (Hamiltonian Adaptation via Meta-Learning), a framework for fast online adaptation of effective Hamiltonian models of superconducting quantum processors. HAML proceeds in two phases. A supervised training phase uses an…

Quantum Physics · Physics 2026-04-29 Arielle Sanford , Andrew T. Kamen , Frederic T. Chong , Andy J. Goldschmidt

Sequential quadratic optimization algorithms are proposed for solving smooth nonlinear optimization problems with equality constraints. The main focus is an algorithm proposed for the case when the constraint functions are deterministic,…

Optimization and Control · Mathematics 2020-07-22 Albert Berahas , Frank E. Curtis , Daniel P. Robinson , Baoyu Zhou

We propose a quantum algorithm for `extremal learning', which is the process of finding the input to a hidden function that extremizes the function output, without having direct access to the hidden function, given only partial input-output…

Generative modeling is a flavor of machine learning with applications ranging from computer vision to chemical design. It is expected to be one of the techniques most suited to take advantage of the additional resources provided by…

Principal component analysis is an important dimension reduction technique in machine learning. In [S. Lloyd, M. Mohseni and P. Rebentrost, Nature Physics 10, 631-633, (2014)], a quantum algorithm to implement principal component analysis…

Quantum Physics · Physics 2019-04-09 Changpeng Shao

The quantum approximate optimization algorithm (QAOA) is a variational quantum algorithm (VQA) ideal for noisy intermediate-scale quantum (NISQ) processors, and is highly successful in solving combinatorial optimization problems (COPs). It…

Quantum Physics · Physics 2026-03-23 Francesco Aldo Venturelli , Sreetama Das , Filippo Caruso

Scaling the size of monolithic quantum computer systems is a difficult task. As the number of qubits within a device increases, a number of factors contribute to decreases in yield and performance. To meet this challenge, distributed…

The Variational Quantum Eigensolver (VQE) algorithm is gaining interest for its potential use in near-term quantum devices. In the VQE algorithm, parameterized quantum circuits (PQCs) are employed to prepare quantum states, which are then…

Quantum Physics · Physics 2023-12-29 Atsushi Matsuo , Yudai Suzuki , Ikko Hamamura , Shigeru Yamashita

Engineering the Hamiltonian of a quantum system is fundamental to the design of quantum systems. Automating Hamiltonian design through gradient-based optimization can dramatically accelerate this process. However, computing the gradients of…

Quantum machine learning (QML) is a discipline that seeks to transfer the advantages of quantum computing to data-driven tasks. However, many studies rely on toy datasets or heavy feature reduction, raising concerns about their scalability.…

Quantum Physics · Physics 2025-04-16 Federico Tiblias , Anna Schroeder , Yue Zhang , Mariami Gachechiladze , Iryna Gurevych

Very little is known about the cost landscape for parametrized Quantum Circuits (PQCs). Nevertheless, PQCs are employed in Quantum Neural Networks and Variational Quantum Algorithms, which may allow for near-term quantum advantage. Such…

Quantum Physics · Physics 2022-09-16 Enrico Fontana , M. Cerezo , Andrew Arrasmith , Ivan Rungger , Patrick J. Coles

Hard Attention Mechanisms (HAMs) effectively filter essential information discretely and significantly boost the performance of machine learning models on large datasets. Nevertheless, they confront the challenge of non-differentiability,…

Quantum Physics · Physics 2024-12-31 Ren-Xin Zhao

The study of variational quantum algorithms (VQCs) has received significant attention from the quantum computing community in recent years. These hybrid algorithms, utilizing both classical and quantum components, are well-suited for noisy…

The rapid progress in quantum computing (QC) and machine learning (ML) has attracted growing attention, prompting extensive research into quantum machine learning (QML) algorithms to solve diverse and complex problems. Designing…

Quantum Physics · Physics 2025-01-13 Samuel Yen-Chi Chen , Huan-Hsin Tseng , Hsin-Yi Lin , Shinjae Yoo

Learning quantum Hamiltonians with high precision is important for quantum physics and quantum information science. We propose a multi-stage neural network framework that significantly enhances Hamiltonian learning precision through…

Quantum Physics · Physics 2025-03-11 Zhengjie Kang , Hao Li , Shuo Wang , Jiaojiao Li , Yuanjie Zhang , Zhihuang Luo

We present hierarchical learning, a novel variational architecture for efficient training of large-scale variational quantum circuits. We test and benchmark our technique for distribution loading with quantum circuit born machines (QCBMs).…

Quantum Physics · Physics 2023-11-23 Hrant Gharibyan , Vincent Su , Hayk Tepanyan

Segment Anything Model (SAM) exhibits remarkable zero-shot segmentation capability; however, its prohibitive computational costs make edge deployment challenging. Although post-training quantization (PTQ) offers a promising compression…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Jing Zhang , Zhikai Li , Chengzhi Hu , Xuewen Liu , Qingyi Gu

It is hoped that quantum computers will offer advantages over classical computers for combinatorial optimization. Here, we introduce a feedback-based strategy for quantum optimization, where the results of qubit measurements are used to…

Quantum Physics · Physics 2023-01-05 Alicia B. Magann , Kenneth M. Rudinger , Matthew D. Grace , Mohan Sarovar

Variational quantum algorithms (VQAs) have emerged as a promising approach for achieving quantum advantage on current noisy intermediate-scale quantum devices. However, their large-scale applications are significantly hindered by…

Quantum Physics · Physics 2026-03-03 Shikun Zhang , Zheng Qin , Yongyou Zhang , Yang Zhou , Rui Li , Chunxiao Du , Zhisong Xiao
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