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Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Federated learning (FL) addresses privacy and data-silo issues in the training of large language models (LLMs). Most prior work focuses on improving the efficiency of federated learning for LLMs (FedLLM). However, security in open federated…

Cryptography and Security · Computer Science 2026-04-21 Mingxiang Tao , Yu Tian , Wenxuan Tu , Yue Yang , Xue Yang , Xiangyan Tang

Large language models (LLMs) and LLM-based agents have been widely deployed in a wide range of applications in the real world, including healthcare diagnostics, financial analysis, customer support, robotics, and autonomous driving,…

Cryptography and Security · Computer Science 2025-05-20 Wenrui Xu , Keshab K. Parhi

Software systems have been evolving rapidly and inevitably introducing bugs at an increasing rate, leading to significant losses in resources consumed by software maintenance. Recently, large language models (LLMs) have demonstrated…

Software Engineering · Computer Science 2024-12-03 Wenqiang Luo , Jacky Wai Keung , Boyang Yang , He Ye , Claire Le Goues , Tegawende F. Bissyande , Haoye Tian , Bach Le

Personalized AI assistants, a hallmark of the human-like capabilities of Large Language Models (LLMs), are a challenging application that intertwines multiple problems in LLM research. Despite the growing interest in the development of…

Computation and Language · Computer Science 2025-06-03 Jisoo Mok , Ik-hwan Kim , Sangkwon Park , Sungroh Yoon

High-stakes decision domains are increasingly exploring the potential of Large Language Models (LLMs) for complex decision-making tasks. However, LLM deployment in real-world settings presents challenges in data security, evaluation of its…

Computers and Society · Computer Science 2025-12-05 Swati Sachan , Theo Miller , Mai Phuong Nguyen

Recent advancements in artificial intelligence (AI), particularly in large language models (LLMs), have unlocked significant potential to enhance the quality and efficiency of medical care. By introducing a novel way to interact with AI and…

Current LLM-based services typically require users to submit raw text regardless of its sensitivity. While intuitive, such practice introduces substantial privacy risks, as unauthorized access may expose personal, medical, or legal…

Cryptography and Security · Computer Science 2026-04-09 Jeongho Yoon , Chanhee Park , Yongchan Chun , Hyeonseok Moon , Heuiseok Lim

The recent progression of Large Language Models (LLMs) has witnessed great success in the fields of data-centric applications. LLMs trained on massive textual datasets showed ability to encode not only context but also ability to provide…

Cryptography and Security · Computer Science 2024-05-24 Mohammed Hassanin , Nour Moustafa

The growing reliance on artificial intelligence (AI) in customer support has significantly improved operational efficiency and user experience. However, traditional machine learning (ML) approaches, which require extensive local training on…

Machine Learning · Computer Science 2025-01-03 Anant Prakash Awasthi , Girdhar Gopal Agarwal , Chandraketu Singh , Rakshit Varma , Sanchit Sharma

Private data, being larger and quality-higher than public data, can greatly improve large language models (LLM). However, due to privacy concerns, this data is often dispersed in multiple silos, making its secure utilization for LLM…

Cryptography and Security · Computer Science 2024-12-24 JiaYing Zheng , HaiNan Zhang , LingXiang Wang , WangJie Qiu , HongWei Zheng , ZhiMing Zheng

The success of large language models (LLMs) facilitate many parties to fine-tune LLMs on their own private data. However, this practice raises privacy concerns due to the memorization of LLMs. Existing solutions, such as utilizing synthetic…

Cryptography and Security · Computer Science 2024-10-11 Wenhao Wang , Xiaoyu Liang , Rui Ye , Jingyi Chai , Siheng Chen , Yanfeng Wang

As large language models (LLMs) evolve, deploying them solely in the cloud or compressing them for edge devices has become inadequate due to concerns about latency, privacy, cost, and personalization. This survey explores a collaborative…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-23 Senyao Li , Haozhao Wang , Wenchao Xu , Rui Zhang , Song Guo , Jingling Yuan , Xian Zhong , Tianwei Zhang , Ruixuan Li

The recent popularity of large language models (LLMs) has brought a significant impact to boundless fields, particularly through their open-ended ecosystem such as the APIs, open-sourced models, and plugins. However, with their widespread…

Machine Learning · Computer Science 2023-08-31 Wentao Ye , Mingfeng Ou , Tianyi Li , Yipeng chen , Xuetao Ma , Yifan Yanggong , Sai Wu , Jie Fu , Gang Chen , Haobo Wang , Junbo Zhao

Recent advancements in Large Language Models (LLMs) have led to increasingly diverse requests, accompanied with varying resource (compute and memory) demands to serve them. However, this in turn degrades the cost-efficiency of LLM serving…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-06 Youhe Jiang , Fangcheng Fu , Xiaozhe Yao , Guoliang He , Xupeng Miao , Ana Klimovic , Bin Cui , Binhang Yuan , Eiko Yoneki

The rapid advancements in Large Language Models (LLMs) have unlocked transformative possibilities in natural language processing, particularly within the financial sector. Financial data is often embedded in intricate relationships across…

Statistical Finance · Quantitative Finance 2026-05-21 Alejandro Lopez-Lira , Jihoon Kwon , Sangwoon Yoon , Jy-yong Sohn , Chanyeol Choi

The emergence of Large Language Models (LLMs) has brought both excitement and concerns to social computing research. On the one hand, LLMs offer unprecedented capabilities in analyzing vast amounts of textual data and generating human-like…

Human-Computer Interaction · Computer Science 2023-07-11 Hong Shen , Tianshi Li , Toby Jia-Jun Li , Joon Sung Park , Diyi Yang

Large language models are rapidly gaining popularity and have been widely adopted in real-world applications. While the quality of training data is essential, privacy concerns arise during data collection. Federated learning offers a…

Large Language Models (LLMs) have fundamentally transformed approaches to Natural Language Processing (NLP) tasks across diverse domains. In healthcare, accurate and cost-efficient text classification is crucial, whether for clinical notes…

Computation and Language · Computer Science 2026-02-16 Hajar Sakai , Sarah S. Lam

Emerging technologies that generate a huge amount of data such as the Internet of Things (IoT) services need latency aware computing platforms to support time-critical applications. Due to the on-demand services and scalability features of…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-24 Ranesh Kumar Naha , Saurabh Garg , Andrew Chan