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Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Accurate cancer survival prediction requires integration of diverse data modalities that reflect the complex interplay between imaging, clinical parameters, and textual reports. However, existing multimodal approaches suffer from simplistic…

Machine Learning · Computer Science 2025-07-01 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

While tumor dynamic modeling has been widely applied to support the development of oncology drugs, there remains a need to increase predictivity, enable personalized therapy, and improve decision-making. We propose the use of Tumor Dynamic…

Quantitative Methods · Quantitative Biology 2023-10-24 Mark Laurie , James Lu

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

The early detection of a pulmonary embolism (PE) is critical for enhancing patient survival rates. Both image-based and non-image-based features are of utmost importance in medical classification tasks. In a clinical setting, physicians…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Zhaoxin Guo , Zhipeng Wang , Ruiquan Ge , Jianxun Yu , Feiwei Qin , Yuan Tian , Yuqing Peng , Yonghong Li , Changmiao Wang

Chest X-ray imaging is a critical diagnostic tool for identifying pulmonary diseases. However, manual interpretation of these images is time-consuming and error-prone. Automated systems utilizing convolutional neural networks (CNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2025-11-25 Saurabh Agarwal , K. V. Arya , Yogesh Kumar Meena

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Lung cancer continues to be the leading cause of cancer-related deaths globally. Early detection and diagnosis of pulmonary nodules are essential for improving patient survival rates. Although previous research has integrated multimodal and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Xiao Yu , Zhaojie Fang , Guanyu Zhou , Yin Shen , Huoling Luo , Ye Li , Ahmed Elazab , Xiang Wan , Ruiquan Ge , Changmiao Wang

Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Yihao Li , Mostafa El Habib Daho , Pierre-Henri Conze , Rachid Zeghlache , Hugo Le Boité , Ramin Tadayoni , Béatrice Cochener , Mathieu Lamard , Gwenolé Quellec

Brain tumor represents one of the most fatal cancers around the world, and is very common in children and the elderly. Accurate identification of the type and grade of tumor in the early stages plays an important role in choosing a precise…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Dunyuan Xu , Xi Wang , Jinyue Cai , Pheng-Ann Heng

Recent works on Multimodal 3D Computer-aided diagnosis have demonstrated that obtaining a competitive automatic diagnosis model when a 3D convolution neural network (CNN) brings more parameters and medical images are scarce remains…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Yin Dai , Yifan Gao , Fayu Liu , Jun Fu

Positron emission tomography (PET) combined with computed tomography (CT) imaging is routinely used in cancer diagnosis and prognosis by providing complementary information. Automatically segmenting tumors in PET/CT images can significantly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Jinpeng Lu , Jingyun Chen , Linghan Cai , Songhan Jiang , Yongbing Zhang

In this work, we propose a multi-modal Convolutional Neural Network (CNN) approach for brain tumor segmentation. We investigate how to combine different modalities efficiently in the CNN framework.We adapt various fusion methods, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-09-21 Mehmet Aygün , Yusuf Hüseyin Şahin , Gözde Ünal

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

Segmentation of head and neck (H\&N) tumours and prediction of patient outcome are crucial for patient's disease diagnosis and treatment monitoring. Current developments of robust deep learning models are hindered by the lack of large…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Emmanuelle Bourigault , Daniel R. McGowan , Abolfazl Mehranian , Bartłomiej W. Papież

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Meng Zhou , Yuxuan Zhang , Xiaolan Xu , Jiayi Wang , Farzad Khalvati
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