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In this paper, we study pairs of oscillators that are indirectly coupled via active (excitable) cells. We introduce a scalar phase model for coupled oscillators and excitable cells. We first show that one excitable and one oscillatory cell…

Dynamical Systems · Mathematics 2019-06-05 Derek Orr , Bard Ermentrout

In the first part of this paper, we showed that three coupled populations of identical phase oscillators give rise to heteroclinic cycles between invariant sets where populations show distinct frequencies. Here, we now give explicit…

Dynamical Systems · Mathematics 2019-08-05 Christian Bick , Alexander Lohse

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

Neurons and Cognition · Quantitative Biology 2021-04-08 R. Janaki , A. S. Vytheeswaran

Oscillatory dynamics of complex networks has recently attracted great attention. In this paper we study pattern formation in oscillatory complex networks consisting of excitable nodes. We find that there exist a few center nodes and small…

Chaotic Dynamics · Physics 2011-11-23 Liao Xuhong , Xia Qinzhi , Qian Yu , Zhang Lisheng , Hu Gang , Mi Yuanyuan

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

We investigate feedback control of the cooperative dynamics of two coupled neural oscillators that is induced merely by external noise. The interacting neurons are modelled as FitzHugh-Nagumo systems with parameter values at which no…

Chaotic Dynamics · Physics 2009-11-11 B. Hauschildt , N. B. Janson , A. Balanov , E. Schoell

Critical branching is a theoretical interaction in-between simple units, such as neuronal elements of the human brain. Zhigalov, Kaplan, and Palva (2016, Clin. Neurophysiol., 127(8), 2882-2889) revealed that neurofeedback flash stimulation…

Neurons and Cognition · Quantitative Biology 2017-02-22 Tom Campbell

Autonomous circadian clocks drive daily rhythms in physiology and behaviour. A network of coupled neurons, the suprachiasmatic nucleus (SCN), serves as a robust self-sustained circadian pacemaker. Synchronization of this timer to the…

Adaptation and Self-Organizing Systems · Physics 2015-05-28 G. Bordyugov , A. E. Granada , H. Herzel

Synchronization of neurons forming a network with a hierarchical structure is essential for the brain to be able to function optimally. In this paper we study synchronization of phase oscillators on the most basic example of such a network,…

Disordered Systems and Neural Networks · Physics 2019-07-29 Diego Garlaschelli , Frank den Hollander , Janusz Meylahn , Benthen Zeegers

We study numerically the effects of time delay in networks of delay-coupled excitable FitzHugh Nagumo systems with dissipation. The generation of periodic self-sustained oscillations and its threshold are analyzed depending on the…

Adaptation and Self-Organizing Systems · Physics 2023-07-19 A. V. Bukh , I. A. Shepelev , E. M. Elizarov , S. S. Muni , E. Schöll , G. I. Strelkova

Neural oscillations are electrical activities of the brain measurable at different frequencies. This paper studies the interaction between the fast and slow processes in the brain. We recorded signals intracranially from the simple Wistar…

Neurons and Cognition · Quantitative Biology 2022-05-12 Evgeniia S. Sevasteeva , Sergei A. Plotnikov , Dmitry R. Belov

A novel theory for cell differentiation is proposed, based on simulations with interacting artificial cells which have metabolic networks within, and divide into two when the final product is accumulated. Results of simulations with coupled…

adap-org · Physics 2015-06-30 Kunihiko Kaneko , Tetsuya Yomo

The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple…

Molecular Networks · Quantitative Biology 2007-05-23 Sandeep Krishna , Anna M. C. Andersson , Szabolcs Semsey , Kim Sneppen

We report on experimental studies of synchronization phenomena in a pair of analog electronic neurons (ENs). The ENs were designed to reproduce the observed membrane voltage oscillations of isolated biological neurons from the…

Chaotic Dynamics · Physics 2009-10-31 R. D. Pinto , P. Varona , A. R. Volkovskii , A. Szucs , Henry D. I. Abarbanel , M. I. Rabinovich

A minimalistic model of the half-center oscillator is proposed. Within it, we consider dynamics of two excitable neurons interacting by means of the excitatory coupling. In the parameter space of the model, we identify the regions of…

Dynamical Systems · Mathematics 2021-03-02 A. G. Korotkov , T. A. Levanova , M. A. Zaks , G. V. Osipov

Pancreatic $\beta$-cells play a central role in maintaining glucose homeostasis through the pulsatile secretion of insulin. This essential function relies not only on intracellular regulatory mechanisms but also on coordinated interactions…

Biological Physics · Physics 2025-12-17 Carine Simo , Venceslas Nguefoue Meli , Patrick Louodop , Samuel Bowong , Thierry Njougouo

For many natural and engineered systems, a central function or design goal is the synchronization of one or more rhythmic or oscillating processes to an external forcing signal, which may be periodic on a different time-scale from the…

Dynamical Systems · Mathematics 2014-01-10 Anatoly Zlotnik , Jr-Shin Li

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

Neurons and Cognition · Quantitative Biology 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

Theta-nested gamma oscillations have been reported in many areas of the brain and are believed to represent a fundamental mechanism to transfer information across spatial and temporal scales. In a series of recent experiments in vitro it…

Neurons and Cognition · Quantitative Biology 2022-06-16 Marco Segneri , Hongjie Bi , Simona Olmi , Alessandro Torcini

In many real-world systems, partial synchronization is the dominant dynamical regime and, in systems such as the brain, is often accompanied by collective oscillations in which multiple overlapping modes interact to produce complex rhythmic…

Adaptation and Self-Organizing Systems · Physics 2026-03-03 Ali Seif , Mina Zarei