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Black-box optimization (BBO) is used in materials design, drug discovery, and hyperparameter tuning in machine learning. The world is experiencing several of these problems. In this review, a factorization machine with quantum annealing or…

Statistical Mechanics · Physics 2026-04-30 Ryo Tamura , Yuya Seki , Yuki Minamoto , Koki Kitai , Yoshiki Matsuda , Shu Tanaka , Koji Tsuda

Quantum computing and machine learning are state-of-the-art technologies that have been investigated intensively in both academia and industry. The hybrid technology of these two ingredients is expected to be a powerful tool to solve…

Quantum Physics · Physics 2026-03-05 Yusuke Hama , Tadashi Kadowaki

Black-box (BB) optimization problems aim to identify an input that maximizes or minimizes the output of a function (the BB function) whose input-output relationship is unknown. Factorization machine with quadratic-optimization annealing…

Machine Learning · Computer Science 2026-01-27 Mayumi Nakano , Yuya Seki , Shuta Kikuchi , Shu Tanaka

The prediction of energetically stable crystal structures formed by a given chemical composition is a central problem in solid-state physics. In principle, the crystalline state of assembled atoms can be determined by optimizing the energy…

Materials Science · Physics 2022-06-01 Minoru Kusaba , Chang Liu , Ryo Yoshida

Factorization machine with quadratic-optimization annealing (FMQA) is a black-box optimization method that combines a factorization machine (FM) surrogate with QUBO-based search by an Ising machine. When FMQA is applied to integer or…

Machine Learning · Computer Science 2026-05-07 Taiga Hayashi , Yuya Seki , Kotaro Terada , Yosuke Mukasa , Shuta Kikuchi , Shu Tanaka

This paper explores the applications of quantum annealing (QA) and classical simulated annealing (SA) to a suite of combinatorial optimization problems in machine learning, namely feature selection, instance selection, and clustering. We…

Quantum Physics · Physics 2025-07-22 Chloe Pomeroy , Aleksandar Pramov , Karishma Thakrar , Lakshmi Yendapalli

The RNA inverse folding problem aims to identify nucleotide sequences that preferentially adopt a given target secondary structure. While various heuristic and machine learning-based approaches have been proposed, many require a large…

Machine Learning · Computer Science 2026-02-19 Shuta Kikuchi , Shu Tanaka

In black-box combinatorial optimization, objective evaluations are often expensive, so high quality solutions must be found under a limited budget. Factorization machine with quantum annealing (FMQA) builds a quadratic surrogate model from…

Machine Learning · Computer Science 2026-02-11 Tetsuro Abe , Masashi Yamashita , Shu Tanaka

Structural prediction for the discovery of novel materials is a long sought after goal of computational physics and materials sciences. The success is rather limited for methods such as the simulated annealing method (SA) that require…

Materials Science · Physics 2023-02-08 Chuannan Li , Hanpu Liang , Yifeng Duan , Zijing Lin

In this paper, we introduce stochastic simulated quantum annealing (SSQA) for large-scale combinatorial optimization problems. SSQA is designed based on stochastic computing and quantum Monte Carlo, which can simulate quantum annealing (QA)…

Quantum Physics · Physics 2024-07-25 Naoya Onizawa , Ryoma Sasaki , Duckgyu Shin , Warren J. Gross , Takahiro Hanyu

Solving continuous variable optimization problems by factorization machine quantum annealing (FMQA) demonstrates the potential of Ising machines to be extended as a solver for integer and real optimization problems. However, the details of…

Quantum Physics · Physics 2024-07-08 Katsuhiro Endo , Kazuaki Z. Takahashi

This paper presents an initialization method that can approximate a given approximate Ising model with a high degree of accuracy using a factorization machine (FM), a machine learning model. The construction of an Ising models using an FM…

Machine Learning · Computer Science 2025-07-03 Yuya Seki , Hyakka Nakada , Shu Tanaka

We propose an annealing scheme usable on modern Ising machines for crystal structures prediction (CSP) by taking into account the general n-body atomic interactions, and in particular three-body interactions which are necessary to simulate…

Flexible Job Shop Scheduling (FJSSP) is a complex optimization problem crucial for real-world process scheduling in manufacturing. Efficiently solving such problems is vital for maintaining competitiveness. This paper introduces Quantum…

Quantum Physics · Physics 2023-12-07 Philipp Schworm , Xiangquian Wu , Matthias Klar , Moritz Glatt , Jan C. Aurich

Quantum computing has emerged as a powerful tool to efficiently solve computational challenges, particularly in simulation and optimisation. However, hardware limitations prevent quantum computers from achieving the full theoretical…

Emerging Technologies · Computer Science 2025-05-01 Hugo Araujo , Xinyi Wang , Mohammad Mousavi , Shaukat Ali

Search-based software engineering (SBSE) addresses critical optimization challenges in software engineering, including the next release problem (NRP) and feature selection problem (FSP). While traditional heuristic approaches and integer…

Software Engineering · Computer Science 2025-07-01 Shuchang Wang , Xiaopeng Qiu , Yingxing Xue , Yanfu Li , Wei Yang

Quantum annealing approximately solves combinatorial optimization problems by leveraging the principles of adiabatic quantum systems. In this approach, the system's Hamiltonian evolves from an initial general state to a problem-specific…

Current quantum annealing (QA) hardware suffers from practical limitations such as finite temperature, sparse connectivity, small qubit numbers, and control error. We propose new algorithms for mapping boolean constraint satisfaction…

Quantum Physics · Physics 2016-03-11 Zhengbing Bian , Fabian Chudak , Robert Israel , Brad Lackey , William G. Macready , Aidan Roy

Machine learning interatomic potentials have revolutionized complex materials design by enabling rapid exploration of material configurational spaces via crystal structure prediction with ab initio accuracy. However, critical challenges…

A flexible job shop scheduling problem (FJSSP) poses a complex optimization task in modeling real-world process scheduling tasks with conflicting objectives. To tackle FJSSPs, approximation methods are employed to ensure solutions are…

Quantum Physics · Physics 2024-08-29 Philipp Schworm , Xiangqian Wu , Matthias Klar , Jan C. Aurich
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