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Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Medical image segmentation is fundamental for biomedical discovery. Existing methods lack generalizability and demand extensive, time-consuming manual annotation for new clinical application. Here, we propose MedSAM-3, a text promptable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Anglin Liu , Rundong Xue , Xu R. Cao , Yifan Shen , Yi Lu , Xiang Li , Qianqian Chen , Jintai Chen

Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

We have witnessed remarkable progress in foundation models in vision tasks. Currently, several recent works have utilized the segmenting anything model (SAM) to boost the segmentation performance in medical images, where most of them focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Haoran Wang , Lian Huai , Wenbin Li , Lei Qi , Xingqun Jiang , Yinghuan Shi

Image segmentation foundation models (SFMs) like Segment Anything Model (SAM) have achieved impressive zero-shot and interactive segmentation across diverse domains. However, they struggle to segment objects with certain structures,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Yixin Zhang , Nicholas Konz , Kevin Kramer , Maciej A. Mazurowski

The rapid rise of large-scale foundation models has reshaped the landscape of image segmentation, with models such as Segment Anything achieving unprecedented versatility across diverse vision tasks. However, previous generations-including…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Tianrun Chen , Runlong Cao , Xinda Yu , Lanyun Zhu , Chaotao Ding , Deyi Ji , Cheng Chen , Qi Zhu , Chunyan Xu , Papa Mao , Ying Zang

Segment Anything Model 2 (SAM 2) has emerged as a powerful tool for video object segmentation and tracking anything. Key components of SAM 2 that drive the impressive video object segmentation performance include a large multistage image…

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Lev Ayzenberg , Raja Giryes , Hayit Greenspan

We introduce SAM3D, a new approach to semi-automatic zero-shot segmentation of 3D images building on the existing Segment Anything Model. We achieve fast and accurate segmentations in 3D images with a four-step strategy involving: user…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Trevor J. Chan , Aarush Sahni , Yijin Fang , Jie Li , Alisha Luthra , Alison Pouch , Chamith S. Rajapakse

Foundation models, such as the Segment Anything Model (SAM), have heightened interest in promptable zero-shot segmentation. Although these models perform strongly on natural images, their behavior on medical data remains insufficiently…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Satrajit Chakrabarty , Ravi Soni

Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George

The interactive segmentation task consists in the creation of object segmentation masks based on user interactions. The most common way to guide a model towards producing a correct segmentation consists in clicks on the object and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Robin Schön , Julian Lorenz , Katja Ludwig , Rainer Lienhart

Segmenting and recognizing diverse object parts is crucial in computer vision and robotics. Despite significant progress in object segmentation, part-level segmentation remains underexplored due to complex boundaries and scarce annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Xinjian Wu , Ruisong Zhang , Jie Qin , Shijie Ma , Cheng-Lin Liu

We introduce SAM2Point, a preliminary exploration adapting Segment Anything Model 2 (SAM 2) for zero-shot and promptable 3D segmentation. SAM2Point interprets any 3D data as a series of multi-directional videos, and leverages SAM 2 for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Ziyu Guo , Renrui Zhang , Xiangyang Zhu , Chengzhuo Tong , Peng Gao , Chunyuan Li , Pheng-Ann Heng

Foundation models refer to artificial intelligence (AI) models that are trained on massive amounts of data and demonstrate broad generalizability across various tasks with high accuracy. These models offer versatile, one-for-many or…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Rina Bao , Erfan Darzi , Sheng He , Chuan-Heng Hsiao , Mohammad Arafat Hussain , Jingpeng Li , Atle Bjornerud , Ellen Grant , Yangming Ou

Segmentation is an essential step for remote sensing image processing. This study aims to advance the application of the Segment Anything Model (SAM), an innovative image segmentation model by Meta AI, in the field of remote sensing image…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Lucas Prado Osco , Qiusheng Wu , Eduardo Lopes de Lemos , Wesley Nunes Gonçalves , Ana Paula Marques Ramos , Jonathan Li , José Marcato Junior

Precision medicine in musculoskeletal imaging requires scalable measurement infrastructure. We developed a modular system that converts routine MRI into standardized quantitative biomarkers suitable for clinical decision support. Promptable…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Gabrielle Hoyer , Michelle W Tong , Rupsa Bhattacharjee , Valentina Pedoia , Sharmila Majumdar

Accurate lesion segmentation is essential in medical image analysis, yet most existing methods are designed for specific anatomical sites or imaging modalities, limiting their generalizability. Recent vision-language foundation models…

Image and Video Processing · Electrical Eng. & Systems 2026-03-30 Guoping Xu , Jayaram K. Udupa , Yubing Tong , Xin Long , Ying Zhang , Jie Deng , Weiguo Lu , You Zhang

Recently, large vision model, Segment Anything Model (SAM), has revolutionized the computer vision field, especially for image segmentation. SAM presented a new promptable segmentation paradigm that exhibit its remarkable zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Chenglong Wang , Dexuan Li , Sucheng Wang , Chengxiu Zhang , Yida Wang , Yun Liu , Guang Yang

Existing volumetric medical image segmentation models are typically task-specific, excelling at specific target but struggling to generalize across anatomical structures or modalities. This limitation restricts their broader clinical use.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Haoyu Wang , Sizheng Guo , Jin Ye , Zhongying Deng , Junlong Cheng , Tianbin Li , Jianpin Chen , Yanzhou Su , Ziyan Huang , Yiqing Shen , Bin Fu , Shaoting Zhang , Junjun He , Yu Qiao