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Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Diffusion models have achieved remarkable progress in generative modelling, particularly in enhancing image quality to conform to human preferences. Recently, these models have also been applied to low-level computer vision for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Ziwei Luo , Fredrik K. Gustafsson , Zheng Zhao , Jens Sjölund , Thomas B. Schön

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

Sparse-view computed tomography (CT) enables fast and low-dose CT imaging, an essential feature for patient-save medical imaging and rapid non-destructive testing. In sparse-view CT, only a few projection views are acquired, causing…

Image and Video Processing · Electrical Eng. & Systems 2024-02-28 Nadja Gruber , Johannes Schwab , Elke Gizewski , Markus Haltmeier

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

Numerical Analysis · Mathematics 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

Diffusion models have emerged as powerful priors for solving inverse problems in computed tomography (CT). In certain applications, such as neutron CT, it can be expensive to collect large amounts of measurements even for a single scan,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Timofey Efimov , Singanallur Venkatakrishnan , Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

In this paper, we introduce a denoising diffusion algorithm to discover microstructures with nonlinear fine-tuned properties. Denoising diffusion probabilistic models are generative models that use diffusion-based dynamics to gradually…

Machine Learning · Computer Science 2023-06-14 Nikolaos N. Vlassis , WaiChing Sun

Diffusion-based sparse-view CT (SVCT) imaging has achieved remarkable advancements in recent years, thanks to its more stable generative capability. However, recovering reliable image content and visually consistent textures is still a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Tianqi Wang , Wenchao Du , Hongyu Yang

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Diffusion models have recently emerged as powerful priors for solving inverse problems. While computed tomography (CT) is theoretically a linear inverse problem, it poses many practical challenges. These include correlated noise, artifact…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Jiayang Shi , Daniel M. Pelt , K. Joost Batenburg

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu

This work is to develop a general framework, namely analytical iterative reconstruction (AIR) method, to incorporate analytical reconstruction (AR) method into iterative reconstruction (IR) method, for enhanced CT image quality and…

Medical Physics · Physics 2016-10-12 Hao Gao

Deep learning has shown impressive results in reducing noise and artifacts in X-ray computed tomography (CT) reconstruction. Self-supervised CT reconstruction methods are especially appealing for real-world applications because they require…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Dirk Elias Schut , Adriaan Graas , Robert van Liere , Tristan van Leeuwen

Objective: X-ray computed tomography employing sparse projection views has emerged as a contemporary technique to mitigate radiation dose. However, due to the inadequate number of projection views, an analytic reconstruction method…

Machine Learning · Computer Science 2025-01-10 Yoseob Han

Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Ruiwen Xing , Thomas Humphries , Dong Si

Magnetic Resonance Imaging (MRI) is a powerful imaging technique widely used for visualizing structures within the human body and in other fields such as plant sciences. However, there is a demand to develop fast 3D-MRI reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Arya Bangun , Zhuo Cao , Alessio Quercia , Hanno Scharr , Elisabeth Pfaehler

Magnetic Resonance Imaging (MRI) is a critical tool in modern medical diagnostics, yet its prolonged acquisition time remains a critical limitation, especially in time-sensitive clinical scenarios. While undersampling strategies can…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mohammed Alsubaie , Wenxi Liu , Linxia Gu , Ovidiu C. Andronesi , Sirani M. Perera , Xianqi Li

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader