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A key question in evolution is how likely a mutant is to take over. This depends on natural selection and on stochastic fluctuations. Population spatial structure can impact mutant fixation probabilities. We introduce a model for structured…

Populations and Evolution · Quantitative Biology 2021-11-23 Loïc Marrec , Irene Lamberti , Anne-Florence Bitbol

Often in the analysis of first-order methods, assuming the existence of a quadratic growth bound (a generalization of strong convexity) facilitates much stronger convergence analysis. Hence the analysis is done twice, once for the general…

Optimization and Control · Mathematics 2019-05-16 Benjamin Grimmer

Diffusion models accomplish remarkable success in data generation tasks across various domains. However, the iterative sampling process is computationally expensive. Consistency models are proposed to learn consistency functions to map from…

Machine Learning · Computer Science 2025-05-07 Yiding Chen , Yiyi Zhang , Owen Oertell , Wen Sun

Deep generative models such as diffusion and flow matching are powerful machine learning tools capable of learning and sampling from high-dimensional distributions. They are particularly useful when the training data appears to be…

High Energy Physics - Phenomenology · Physics 2026-04-30 Zachary Bogorad , Ibrahim Elsharkawy , Yonatan Kahn , Andrew J. Larkoski , Noam Levi

We study the evolution of gene frequencies in a population living in $\mathbb{R}^d$, modelled by the spatial Lambda Fleming-Viot process with natural selection (Barton, Etheridge and Veber, 2010 and Etheridge, Veber and Yu, 2014). We…

Probability · Mathematics 2022-10-04 Raphaël Forien , Sarah Penington

We present a stochastic version of the mean-shift clustering algorithm. In this stochastic version a randomly chosen sequence of data points move according to partial gradient ascent steps of the objective function. Theoretical results…

Machine Learning · Computer Science 2025-11-13 Itshak Lapidot , Yann Sepulcre , Tom Trigano

We present a general theory of stochastic model reduction which is based on a normal form coordinate transform method of A.J. Roberts. This nonlinear, stochastic projection allows for the deterministic and stochastic dynamics to interact…

Dynamical Systems · Mathematics 2017-11-22 Eric Forgoston , Lora Billings , Ira B. Schwartz

The notion of periodic two-scale convergence and the method of periodic unfolding are prominent and useful tools in multiscale modeling and analysis of PDEs with rapidly oscillating periodic coefficients. In this paper we are interested in…

Analysis of PDEs · Mathematics 2021-05-28 Martin Heida , Stefan Neukamm , Mario Varga

We develop a general modelling framework for compartmental epidemiological systems structured by continuous variables which are linked to the levels of expression of compartment-specific traits. We start by formulating an individual-based…

Populations and Evolution · Quantitative Biology 2025-08-14 Emanuele Bernardi , Tommaso Lorenzi , Mattia Sensi , Andrea Tosin

We study the existence and stability of propagating fronts in Meinhardt's multivariable reaction-diffusion model of branching in one spatial dimension. We identify a saddle-node-infinite-period (SNIPER) bifurcation of fronts that leads to…

Pattern Formation and Solitons · Physics 2023-05-18 Edgar Knobloch , Arik Yochelis

Motivated by the need for analysing large spatio-temporal panel data, we introduce a novel dimensionality reduction methodology for $n$-dimensional random fields observed across a number $S$ spatial locations and $T$ time periods. We call…

Methodology · Statistics 2023-12-06 Matteo Barigozzi , Davide La Vecchia , Hang Liu

Diffusion models have emerged as powerful tools for generative modeling, demonstrating exceptional capability in capturing target data distributions from large datasets. However, fine-tuning these massive models for specific downstream…

Machine Learning · Computer Science 2025-09-01 Yinbin Han , Meisam Razaviyayn , Renyuan Xu

The first chapter concerns monotype population models. We first study general birth and death processes and we give non-explosion and extinction criteria, moment computations and a pathwise representation. We then show how different scales…

Probability · Mathematics 2017-07-06 Vincent Bansaye , Sylvie Méléard

While momentum-based accelerated variants of stochastic gradient descent (SGD) are widely used when training machine learning models, there is little theoretical understanding on the generalization error of such methods. In this work, we…

Machine Learning · Computer Science 2024-01-17 Ali Ramezani-Kebrya , Kimon Antonakopoulos , Volkan Cevher , Ashish Khisti , Ben Liang

Here we show that a particular one-parameter generalization of the exponential function is suitable to unify most of the popular one-species discrete population dynamics models into a simple formula. A physical interpretation is given to…

Biological Physics · Physics 2009-10-20 Alexandre Souto Martinez , Rodrigo Silva Gonzalez , Aquino Lauri Espindola

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

This paper introduces the Generalized Space-Time Fractional Skellam Process (GSTFSP) and the Generalized Space Fractional Skellam Process (GSFSP). We investigate their distributional properties including the probability generating function…

Probability · Mathematics 2025-04-14 Kartik Tathe , Sayan Ghosh

Modeling transformations between arbitrary data distributions is a fundamental scientific challenge, arising in applications like drug discovery and evolutionary simulation. While flow matching offers a natural framework for this task, its…

Machine Learning · Computer Science 2025-10-09 Shiye Su , Yuhui Zhang , Linqi Zhou , Rajesh Ranganath , Serena Yeung-Levy

Conventional diffusion models typically relies on a fixed forward process, which implicitly defines complex marginal distributions over latent variables. This can often complicate the reverse process' task in learning generative…

Machine Learning · Statistics 2025-06-10 Grigory Bartosh , Dmitry Vetrov , Christian A. Naesseth

We consider the long-time behavior of the mean curvature flow in heterogeneous media with periodic fibrations, modeled as an additive driving force. Under appropriate assumptions on the forcing term, we show existence of generalized…

Analysis of PDEs · Mathematics 2011-10-13 Annalisa Cesaroni , Matteo Novaga