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Multi-annotator medical image segmentation is an important research problem, but requires annotated datasets that are expensive to collect. Dermoscopic skin lesion imaging allows human experts and AI systems to observe morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Kumar Abhishek , Jeremy Kawahara , Ghassan Hamarneh

Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Soham Bhosale , Arjun Krishna , Ge Wang , Klaus Mueller

A major challenge in the segmentation of medical images is the large inter- and intra-observer variability in annotations provided by multiple experts. To address this challenge, we propose a novel method for multi-expert prediction using…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Tomer Amit , Shmuel Shichrur , Tal Shaharabany , Lior Wolf

Recently, automated medical image segmentation methods based on deep learning have achieved great success. However, they heavily rely on large annotated datasets, which are costly and time-consuming to acquire. Few-shot learning aims to…

Artificial Intelligence · Computer Science 2024-08-20 Jiayu Huo , Ruiqiang Xiao , Haotian Zheng , Yang Liu , Sebastien Ourselin , Rachel Sparks

Segmenting skin lesions images is relevant both for itself and for assisting in lesion classification, but suffers from the challenge in obtaining annotated data. In this work, we show that segmentation may improve with less data, by…

Computer Vision and Pattern Recognition · Computer Science 2020-04-30 Vinicius Ribeiro , Sandra Avila , Eduardo Valle

In clinical practice, segmenting specific lesions based on the needs of physicians can significantly enhance diagnostic accuracy and treatment efficiency. However, conventional lesion segmentation models lack the flexibility to distinguish…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shuyi Ouyang , Jinyang Zhang , Xiangye Lin , Xilai Wang , Qingqing Chen , Yen-Wei Chen , Lanfen Lin

Medical image segmentation exhibits intra- and inter-annotator variability due to ambiguous object boundaries, annotator preferences, expertise, and tools, among other factors. Lesions with ambiguous boundaries, e.g., spiculated or…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Kumar Abhishek , Jeremy Kawahara , Ghassan Hamarneh

Segmentation uncertainty models predict a distribution over plausible segmentations for a given input, which they learn from the annotator variation in the training set. However, in practice these annotations can differ systematically in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Kilian Zepf , Eike Petersen , Jes Frellsen , Aasa Feragen

An often overlooked problem in medical image segmentation research is the effective selection of training subsets to annotate from a complete set of unlabelled data. Many studies select their training sets at random, which may lead to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Stephen Lloyd-Brown , Susan Francis , Caroline Hoad , Penny Gowland , Karen Mullinger , Andrew French , Xin Chen

Computer-aided diagnosis systems for classification of different type of skin lesions have been an active field of research in recent decades. It has been shown that introducing lesions and their attributes masks into lesion classification…

Computer Vision and Pattern Recognition · Computer Science 2019-04-01 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Ali Gooya , Nasir Rajpoot

Label scarcity has been a long-standing issue for biomedical image segmentation, due to high annotation costs and professional requirements. Recently, active learning (AL) strategies strive to reduce annotation costs by querying a small…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Ziyuan Zhao , Wenjing Lu , Zeng Zeng , Kaixin Xu , Bharadwaj Veeravalli , Cuntai Guan

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Large, fine-grained image segmentation datasets, annotated at pixel-level, are difficult to obtain, particularly in medical imaging, where annotations also require expert knowledge. Weakly-supervised learning can train models by relying on…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Gabriele Valvano , Andrea Leo , Sotirios A. Tsaftaris

Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art…

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

In this work, we explore the issue of the inter-annotator agreement for training and evaluating automated segmentation of skin lesions. We explore what different degrees of agreement represent, and how they affect different use cases for…

Computer Vision and Pattern Recognition · Computer Science 2019-06-07 Vinicius Ribeiro , Sandra Avila , Eduardo Valle

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

Accurate segmentation of skin lesions within dermoscopic images plays a crucial role in the timely identification of skin cancer for computer-aided diagnosis on mobile platforms. However, varying shapes of the lesions, lack of defined…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Hamza Farooq , Zuhair Zafar , Ahsan Saadat , Tariq M Khan , Shahzaib Iqbal , Imran Razzak

Semantic segmentation requires large amounts of pixel-wise annotations to learn accurate models. In this paper, we present a video prediction-based methodology to scale up training sets by synthesizing new training samples in order to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-04 Yi Zhu , Karan Sapra , Fitsum A. Reda , Kevin J. Shih , Shawn Newsam , Andrew Tao , Bryan Catanzaro

Lesion segmentation is inherently influenced by imaging uncertainty, arising from ill-defined lesion boundaries and inter-observer variability in diagnosis. To address this challenge, previous works formulated the multi-rater medical image…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ke Liu , Shangde Gao , Yichao Fu , Shuaike Shen , Shangqi Gao , Chunhua Shen
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