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Human-in-the-loop validation is essential in safety-critical clinical AI, yet the transition between initial model inference and expert correction is rarely analyzed as a structured signal. We introduce a diagnostic alignment framework in…

Artificial Intelligence · Computer Science 2026-02-27 Dimitrios P. Panagoulias , Evangelia-Aikaterini Tsichrintzi , Georgios Savvidis , Evridiki Tsoureli-Nikita

The Sharp/van der Heijde (SvdH) score has been widely used in clinical trials to quantify radiographic damage in Rheumatoid Arthritis (RA), but its complexity has limited its adoption in routine clinical practice. To address the…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Zhiyan Bo , Laura C. Coates , Bartlomiej W. Papiez

Osteoporosis, a prevalent condition among the aging population worldwide, is characterized by diminished bone mass and altered bone structure, increasing susceptibility to fractures. It poses a significant and growing global public health…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Vijaya Kalavakonda , Vimaladevi Madhivanan , Abhay Lal , Senthil Rithika , Shamala Karupusamy Subramaniam , Mohamed Sameer

Along with rich health-related metadata, medical images have been acquired for over 40,000 male and female UK Biobank participants, aged 44-82, since 2014. Phenotypes derived from these images, such as measurements of body composition from…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Taro Langner , Fredrik K. Gustafsson , Benny Avelin , Robin Strand , Håkan Ahlström , Joel Kullberg

Random feature ridge regression is often analyzed in the high-dimensional regime under the homogeneous sampling model $x_i=\Sigma^{1/2}x_i'$, where the vectors $x_i'$ have iid entries and the same covariance matrix $\Sigma$ is shared by all…

Machine Learning · Statistics 2026-05-19 Issa-Mbenard Dabo , Jérémie Bigot

We propose a model of brain atrophy as a function of high-dimensional genetic information and low dimensional covariates such as gender, age, APOE gene, and disease status. A nonparametric single-index Bayesian model of high dimension is…

Methodology · Statistics 2019-11-11 Arkaprava Roy , Subhashis Ghosal , Kingshuk Roy Choudhury

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Ultrasound-based fetal biometric measurements, such as head circumference (HC) and biparietal diameter (BPD), are commonly used to evaluate the gestational age and diagnose fetal central nervous system (CNS) pathology. Since manual…

Medical Physics · Physics 2019-06-06 Hwa Pyung Kim , Sung Min Lee , Ja-Young Kwon , Yejin Park , Kang Cheol Kim , Jin Keun Seo

Hyperspectral image (HSI) super-resolution without additional auxiliary image remains a constant challenge due to its high-dimensional spectral patterns, where learning an effective spatial and spectral representation is a fundamental…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Kaiwei Zhang

Based on CT and MRI images acquired from normal pressure hydrocephalus (NPH) patients, using machine learning methods, we aim to establish a multi-modal and high-performance automatic ventricle segmentation method to achieve efficient and…

Medical Physics · Physics 2022-02-02 Xi Zhou , Qinghao Ye , Xiaolin Yang , Jiakuan Chen , Haiqin Ma , Jun Xia , Javier Del Ser , Guang Yang

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

Computation and Language · Computer Science 2022-01-13 Haoran Shi , Pengtao Xie , Zhiting Hu , Ming Zhang , Eric P. Xing

An individualized decision rule (IDR) is a decision function that assigns each individual a given treatment based on his/her observed characteristics. Most of the existing works in the literature consider settings with binary or finitely…

Methodology · Statistics 2023-01-31 Hengrui Cai , Chengchun Shi , Rui Song , Wenbin Lu

Inverse inference, or "brain reading", is a recent paradigm for analyzing functional magnetic resonance imaging (fMRI) data, based on pattern recognition and statistical learning. By predicting some cognitive variables related to brain…

Deep learning-based quality metrics have recently given significant improvement in Image Quality Assessment (IQA). In the field of stereoscopic vision, information is evenly distributed with slight disparity to the left and right eyes.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-04 Oussama Messai , Aladine Chetouani

Fluctuations in heart rate are intimately tied to changes in the physiological state of the organism. We examine and exploit this relationship by classifying a human subject's wake/sleep status using his instantaneous heart rate (IHR)…

Applications · Statistics 2018-08-02 John Malik , Yu-Lun Lo , Hau-tieng Wu

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Manual prescription of the field of view (FOV) by MRI technologists is variable and prolongs the scanning process. Often, the FOV is too large or crops critical anatomy. We propose a deep-learning framework, trained by radiologists'…

Image and Video Processing · Electrical Eng. & Systems 2022-11-10 Ke Lei , Ali B. Syed , Xucheng Zhu , John M. Pauly , Shreyas S. Vasanawala

Early diagnosis of Alzheimer's disease and its prodromal stage, also known as mild cognitive impairment (MCI), is critical since some patients with progressive MCI will develop the disease. We propose a multi-stream deep convolutional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Mona Ashtari-Majlan , Abbas Seifi , Mohammad Mahdi Dehshibi

Intracerebral Hemorrhage (ICH) is the deadliest subtype of stroke, necessitating timely and accurate prognostic evaluation to reduce mortality and disability. However, the multi-factorial nature and complexity of ICH make methods based…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Xinlei Yu , Xinyang Li , Ruiquan Ge , Shibin Wu , Ahmed Elazab , Jichao Zhu , Lingyan Zhang , Gangyong Jia , Taosheng Xu , Xiang Wan , Changmiao Wang

Magnetic resonance imaging~(MRI) have played a crucial role in brain disease diagnosis, with which a range of computer-aided artificial intelligence methods have been proposed. However, the early explorations usually focus on the limited…

Computer Vision and Pattern Recognition · Computer Science 2023-09-14 Jiayu Lei , Lisong Dai , Haoyun Jiang , Chaoyi Wu , Xiaoman Zhang , Yao Zhang , Jiangchao Yao , Weidi Xie , Yanyong Zhang , Yuehua Li , Ya Zhang , Yanfeng Wang