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We build and study an individual based model of the telomere length's evolution in a population across multiple generations. This model is a continuous time typed branching process, where the type of an individual includes its gamete mean…

Populations and Evolution · Quantitative Biology 2023-11-17 Athanasios Benetos , Olivier Coudray , Anne Gégout-Petit , Lionel Lenôtre , Simon Toupance , Denis Villemonais

Branching processes are models used to describe populations that reproduce and die over time. In the classical setting, an individual's reproductive capacity remains constant throughout its lifetime. However, in real-world situations,…

Probability · Mathematics 2026-02-27 Daniela Bertacchi , Elena Montanaro , Fabio Zucca

Replicative senescence, induced by telomere shortening, exhibits considerable asynchrony and heterogeneity, the origins of which remain unclear. Here, we formally study how telomere shortening mechanisms impact on senescence kinetics and…

Genomics · Quantitative Biology 2016-11-08 Sarah Eugène , Thibault Bourgeron , Zhou Xu

Branching processes are classical growth models in cell kinetics. In their construction, it is usually assumed that cell lifetimes are independent random variables, which has been proved false in experiments. Models of dependent lifetimes…

Populations and Evolution · Quantitative Biology 2013-07-02 Sana Louhichi , Bernard Ycart

We consider a branching model in discrete time where each individual has a trait in some general state space. Both the reproduction law and the trait inherited by the offsprings may depend on the trait of the mother and the environment. We…

Probability · Mathematics 2013-11-26 Vincent Bansaye

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Machine Learning · Computer Science 2019-03-06 Emma Pierson , Pang Wei Koh , Tatsunori Hashimoto , Daphne Koller , Jure Leskovec , Nicholas Eriksson , Percy Liang

We study age-structured branching models with reproduction law depending on the remaining lifetime of the parent. The lifespan of an individual is decided at its birth and its remaining lifetime decreases at the unit speed. The models…

Probability · Mathematics 2024-01-08 Ziling Cheng , Zenghu Li

We consider a class of Crump-Mode-Jagers processes with interaction, constructed by removing a newly born offspring with a probability that depends on the age structure of the population at its birth time. We prove a law of large numbers…

Probability · Mathematics 2025-11-14 Félix Foutel-Rodier , Emmanuel Schertzer

We propose a modelling framework to analyse the stochastic behaviour of heterogeneous, multi-scale cellular populations. We illustrate our methodology with a particular example in which we study a population with an oxygen-regulated…

Biological Physics · Physics 2017-09-01 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Evolutionary branching is analysed in a stochastic, individual-based population model under mutation and selection. In such models, the common assumption is that individual reproduction and life career are characterised by values of a…

Populations and Evolution · Quantitative Biology 2025-10-01 S. Sagitov , B. Mehlig , P. Jagers , V. Vatutin

By introducing the notions of living and dead nodes a new model of random tree evolution with continuous time parameter has been constructed. It is assumed that two random variables, the lifetime and the offspring number of living nodes…

Statistical Mechanics · Physics 2007-05-23 L. Pal

We present a modelling approach for diffusion in a complex medium characterized by a random length scale. The resulting stochastic process shows subdiffusion with a behavior in qualitative agreement with single particle tracking experiments…

Statistical Mechanics · Physics 2016-12-14 Daniel Molina-García , Tuan Minh Pham , Paolo Paradisi , Carlo Manzo , Gianni Pagnini

We study the nonparametric estimation of the branching rate $B(x)$ of a supercritical Bellman-Harris population: a particle with age $x$ has a random lifetime governed by $B(x)$; at its death time, it gives rise to $k \geq 2$ children with…

Other Statistics · Statistics 2015-10-14 Marc Hoffmann , Adélaïde Olivier

We study the exponential growth of bifurcating processes with ancestral dependence. We suppose here that the lifetimes of the cells are dependent random variables, that the numbers of new cells are random and dependent. Lifetimes and new…

Probability · Mathematics 2017-01-04 Loïc Hervé , Sana Louhichi , Françoise Pène

We present an individual based model of evolutionary ecology. The reproduction rate of individuals characterized by their genome depends on the composition of the population in genotype space. Ecological features such as the taxonomy and…

Statistical Mechanics · Physics 2016-08-31 Matt Hall , Kim Christensen , Simone A. di Collobiano , Henrik Jeldtoft Jensen

We study a density-dependent Markov jump process describing a population where each individual is characterized by a type, and reproduces at rates depending both on its type and on the population type distribution. We are interested in the…

Probability · Mathematics 2026-02-26 Madeleine Kubasch

A discrete time branching process where the offspring distribution is generation-dependent, and the number of reproductive individuals is controlled by a random mechanism is considered. This model is a Markov chain but, in general, the…

Probability · Mathematics 2024-01-30 Miguel González , Carmen Minuesa , Manuel Mota , Inés del Puerto , Alfonso Ramos

The GREM-like trap model is a continuous time Markov jump process on the leaves of a finite volume $L$-level tree whose transition rates depend on a trapping landscape built on the vertices of the whole tree. We prove that the natural…

Probability · Mathematics 2015-01-14 Véronique Gayrard , Onur Gün

A density-dependent branching process is a particle system in which individuals reproduce independently, but in a way that depends on the current population size. This feature can model a wide range of ecological interactions at the cost of…

Probability · Mathematics 2026-01-23 Mathilde André , Félix Foutel-Rodier , Emmanuel Schertzer

Stem cells, through their ability to produce daughter stem cells and differentiate into specialized cells, are essential in the growth, maintenance, and repair of biological tissues. Understanding the dynamics of cell populations in the…

Applications · Statistics 2026-02-02 Huyen Nguyen , Haim Bar , Zhiyi Chi , Vladimir Pozdnyakov
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