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Related papers: MedSyn: LLM-based Synthetic Medical Text Generatio…

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Collecting high-quality training data is essential for fine-tuning Large Language Models (LLMs). However, acquiring such data is often costly and time-consuming, especially for non-English languages such as Italian. Recently, researchers…

Computation and Language · Computer Science 2025-04-01 Fatemeh Mohammadi , Tommaso Romano , Samira Maghool , Paolo Ceravolo

AI systems in healthcare research have shown potential to increase patient throughput and assist clinicians, yet progress is constrained by limited access to real patient data. To address this issue, we present a zero-shot, knowledge-guided…

The success of Large Language Models (LLMs) is inherently linked to the availability of vast, diverse, and high-quality data for training and evaluation. However, the growth rate of high-quality data is significantly outpaced by the…

Computation and Language · Computer Science 2024-10-18 Ke Wang , Jiahui Zhu , Minjie Ren , Zeming Liu , Shiwei Li , Zongye Zhang , Chenkai Zhang , Xiaoyu Wu , Qiqi Zhan , Qingjie Liu , Yunhong Wang

Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Synthetic data generation with Large Language Models (LLMs) has emerged as a promising solution in the medical domain to mitigate data scarcity and privacy constraints. However, existing approaches remain constrained by their derivative…

Artificial Intelligence · Computer Science 2026-01-07 Yunghwei Lai , Ziyue Wang , Weizhi Ma , Yang Liu

The widespread use of big data across sectors has raised major privacy concerns, especially when sensitive information is shared or analyzed. Regulations such as GDPR and HIPAA impose strict controls on data handling, making it difficult to…

Machine Learning · Computer Science 2025-12-10 Anantaa Kotal , Anupam Joshi

Large Language Models (LLMs) raise concerns about lowering the cost of generating texts that could be used for unethical or illegal purposes, especially on social media. This paper investigates the promise of such models to help enforce…

Computers and Society · Computer Science 2024-03-25 Thales Bertaglia , Lily Heisig , Rishabh Kaushal , Adriana Iamnitchi

Many sensitive domains -- such as the clinical domain -- lack widely available datasets due to privacy risks. The increasing generative capabilities of large language models (LLMs) have made synthetic datasets a viable path forward. In this…

Computation and Language · Computer Science 2025-06-03 Thomas Vakili , Aron Henriksson , Hercules Dalianis

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Machine Learning · Computer Science 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

High computation costs and latency of large language models such as GPT-4 have limited their deployment in clinical settings. Small language models (SLMs) offer a cost-effective alternative, but their limited capacity requires biomedical…

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

Medical Vision-Language Pre-training (VLP) learns representations jointly from medical images and paired radiology reports. It typically requires large-scale paired image-text datasets to achieve effective pre-training for both the image…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Che Liu , Anand Shah , Wenjia Bai , Rossella Arcucci

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

Large language models (LLMs) have shown impressive performance on general-purpose tasks, yet adapting them to specific domains remains challenging due to the scarcity of high-quality domain data. Existing data synthesis tools often struggle…

Computation and Language · Computer Science 2025-07-08 Ziyang Miao , Qiyu Sun , Jingyuan Wang , Yuchen Gong , Yaowei Zheng , Shiqi Li , Richong Zhang

Large language models (LLMs) have great potential for synthetic data generation. This work shows that useful data can be synthetically generated even for tasks that cannot be solved directly by LLMs: for problems with structured outputs, it…

Computation and Language · Computer Science 2023-10-31 Martin Josifoski , Marija Sakota , Maxime Peyrard , Robert West

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Generating synthetic images is an art which emulates the natural process of image generation in a closest possible manner. In this work, we exploit such a framework for data generation in handwritten domain. We render synthetic data using…

Computer Vision and Pattern Recognition · Computer Science 2016-08-16 Praveen Krishnan , C. V. Jawahar

Synthetic data augmentation via large language models (LLMs) allows researchers to leverage additional training data, thus enhancing the performance of downstream tasks, especially when real-world data is scarce. However, the generated data…

Machine Learning · Computer Science 2025-03-25 Hsun-Yu Kuo , Yin-Hsiang Liao , Yu-Chieh Chao , Wei-Yun Ma , Pu-Jen Cheng

Sensitive medical data is often subject to strict usage constraints. In this paper, we trained a generative adversarial network (GAN) on real-world electronic health records (EHR). It was then used to create a data-set of "fake" patients…

Machine Learning · Computer Science 2021-09-07 John Weldon , Tomas Ward , Eoin Brophy
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