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One of the central aims of neuroscience is to reliably predict the behavioral response of an organism using its neural activity. If possible, this implies we can causally manipulate the neural response and design brain-computer-interface…

Neurons and Cognition · Quantitative Biology 2025-04-01 Jayanth R Taranath

Human learning is a complex phenomenon that requires adaptive processes across a range of temporal and spacial scales. While our understanding of those processes at single scales has increased exponentially over the last few years, a…

Neurons and Cognition · Quantitative Biology 2016-09-08 Marcelo G. Mattar , Danielle S. Bassett

Advances in simultaneous recordings of large numbers of neurons have driven significant interest in the structure of neural population activity such as dimension. A key question is how these dynamic features arise mechanistically and their…

Neurons and Cognition · Quantitative Biology 2025-08-08 Xuanyu Shen , Yu Hu

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

The last decades saw dramatic progress in brain research. These advances were often buttressed by probing single variables to make circumscribed discoveries, typically through null hypothesis significance testing. New ways for generating…

Neurons and Cognition · Quantitative Biology 2019-03-26 Danilo Bzdok , John Ioannidis

The principles of neural encoding and computations are inherently collective and usually involve large populations of interacting neurons with highly correlated activities. While theories of neural function have long recognized the…

Neurons and Cognition · Quantitative Biology 2019-05-14 Christophe Gardella , Olivier Marre , Thierry Mora

Heteroclinic cycles are widely used in neuroscience in order to mathematically describe different mechanisms of functioning of the brain and nervous system. Heteroclinic cycles and interactions between them can be a source of different…

Adaptation and Self-Organizing Systems · Physics 2023-12-15 Artyom E. Emelin , Evgeny A. Grines , Tatiana A. Levanova

Noise-assisted transport phenomena highlight the nontrivial interplay between environmental effects and quantum coherence in achieving maximal efficiency. Due to the complexity of biochemical systems and their environments, effective open…

Neural-network models of high-level brain functions such as memory recall and reasoning often rely on the presence of stochasticity. The majority of these models assumes that each neuron in the functional network is equipped with its own…

Neurons and Cognition · Quantitative Biology 2022-05-17 Jakob Jordan , Mihai A. Petrovici , Oliver Breitwieser , Johannes Schemmel , Karlheinz Meier , Markus Diesmann , Tom Tetzlaff

This paper investigates the origin and onset of chaos in a mathematical model of an individual neuron, arising from the intricate interaction between 3D fast and 2D slow dynamics governing its intrinsic currents. Central to the chaotic…

Dynamical Systems · Mathematics 2024-11-12 James Scully , Carter Hinsley , David Bloom , Hil G. E. Meijer , Andrey L. Shilnikov

Recent advancements in measurement techniques have resulted in an increasing amount of data on neural activities recorded in parallel, revealing largely heterogeneous correlation patterns across neurons. Yet, the mechanistic origin of this…

Disordered Systems and Neural Networks · Physics 2024-04-26 Moritz Layer , Moritz Helias , David Dahmen

Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities…

Quantitative Methods · Quantitative Biology 2020-01-01 Ryan E. Langendorf , Debra S. Goldberg

Computational modeling plays an increasingly important role in neuroscience, highlighting the philosophical question of how computational models explain. In the context of neural network models for neuroscience, concerns have been raised…

Neurons and Cognition · Quantitative Biology 2021-04-15 Rosa Cao , Daniel Yamins

Modern neuroscience has evolved into a frontier field that draws on numerous disciplines, resulting in the flourishing of novel conceptual frames primarily inspired by physics and complex systems science. Contributing in this direction, we…

Neurons and Cognition · Quantitative Biology 2024-12-09 Giampiero Bardella , Simone Franchini , Pierpaolo Pani , Stefano Ferraina

In realistic neural circuits, both neurons and synapses are coupled in dynamics with separate time scales. The circuit functions are intimately related to these coupled dynamics. However, it remains challenging to understand the intrinsic…

Neurons and Cognition · Quantitative Biology 2025-11-11 Wenkang Du , Haiping Huang

Neuroscience research is undergoing a minor revolution. Recent advances in machine learning and artificial intelligence (AI) research have opened up new ways of thinking about neural computation. Many researchers are excited by the…

Neurons and Cognition · Quantitative Biology 2020-04-20 Andrew Saxe , Stephanie Nelli , Christopher Summerfield

Present day computers expend orders of magnitude more computational resources to perform various cognitive and perception related tasks that humans routinely perform everyday. This has recently resulted in a seismic shift in the field of…

Emerging Technologies · Computer Science 2017-12-22 Abhronil Sengupta , Kaushik Roy

Synaptic plasticity allows cortical circuits to learn new tasks and to adapt to changing environments. How do cortical circuits use plasticity to acquire functions such as decision-making or working memory? Neurons are connected in complex…

Neurons and Cognition · Quantitative Biology 2023-03-08 Néstor Parga , Luis Serrano-Fernández , Joan Falcó-Roget

We examine the dynamical evolution of the state of a neurone, with particular care to the non-equilibrium nature of the forces influencing its movement in state space. We combine non-equilibrium statistical mechanics and dynamical systems…

Neurons and Cognition · Quantitative Biology 2021-02-19 Dalton A R Sakthivadivel

Functional connectivity is a fundamental property of neural networks that quantifies the segregation and integration of information between cortical areas. Due to mathematical complexity, a theory that could explain how the parameters of…

Neurons and Cognition · Quantitative Biology 2016-05-27 Diego Fasoli , Anna Cattani , Stefano Panzeri