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Related papers: DiReCT: Diagnostic Reasoning for Clinical Notes vi…

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Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Reasoning-enabled LLMs perform strongly on medical reasoning benchmarks, but it remains unclear whether these gains transfer to structured clinical documentation; we investigate this question using SOAP note generation from clinical…

Computation and Language · Computer Science 2026-05-26 Faizan Faisal

Improving performance on complex tasks and enabling interpretable decision making in large language models (LLMs), especially for clinical applications, requires effective reasoning. Yet this remains challenging without supervised…

Computation and Language · Computer Science 2025-05-26 Che Liu , Haozhe Wang , Jiazhen Pan , Zhongwei Wan , Yong Dai , Fangzhen Lin , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

Collecting labeled datasets in finance is challenging due to scarcity of domain experts and higher cost of employing them. While Large Language Models (LLMs) have demonstrated remarkable performance in data annotation tasks on general…

Computation and Language · Computer Science 2024-03-28 Toyin Aguda , Suchetha Siddagangappa , Elena Kochkina , Simerjot Kaur , Dongsheng Wang , Charese Smiley , Sameena Shah

A decade of rapid advances in artificial intelligence (AI) has opened new opportunities for clinical decision support systems (CDSS), with large language models (LLMs) demonstrating strong reasoning abilities on timely medical tasks.…

Computation and Language · Computer Science 2025-11-25 Heejoon Koo

The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu

This study compares the efficacy of GPT-4 and clinalytix Medical AI in predicting the clinical risk of delirium development. Findings indicate that GPT-4 exhibited significant deficiencies in identifying positive cases and struggled to…

Computation and Language · Computer Science 2024-09-17 Mohamed Rezk , Patricia Cabanillas Silva , Fried-Michael Dahlweid

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

Evaluating reasoning ability in Large Language Models (LLMs) is important for advancing artificial intelligence, as it transcends mere linguistic task performance. It involves understanding whether these models truly understand information,…

Artificial Intelligence · Computer Science 2025-10-29 Benjamin Grando Moreira

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

Large language models (LLMs) offer significant potential in enhancing psychiatric practice, from improving diagnostic accuracy to streamlining clinical documentation and therapeutic support. However, existing evaluation resources heavily…

Computation and Language · Computer Science 2025-11-25 Aya E. Fouda , Abdelrahamn A. Hassan , Radwa J. Hanafy , Mohammed E. Fouda

As Large Language Models (LLMs) become increasingly integrated into our everyday lives, understanding their ability to comprehend human mental states becomes critical for ensuring effective interactions. However, despite the recent attempts…

Computation and Language · Computer Science 2023-12-06 Kanishk Gandhi , Jan-Philipp Fränken , Tobias Gerstenberg , Noah D. Goodman

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

Computation and Language · Computer Science 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

The meaningful use of electronic health records (EHR) continues to progress in the digital era with clinical decision support systems augmented by artificial intelligence. A priority in improving provider experience is to overcome…

Computation and Language · Computer Science 2023-01-30 Yanjun Gao , Dmitriy Dligach , Timothy Miller , John Caskey , Brihat Sharma , Matthew M Churpek , Majid Afshar

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Large Language Models (LLMs) are increasingly used in tasks requiring interpretive and inferential accuracy. In this paper, we introduce ExpliCa, a new dataset for evaluating LLMs in explicit causal reasoning. ExpliCa uniquely integrates…

Computation and Language · Computer Science 2026-02-10 Martina Miliani , Serena Auriemma , Alessandro Bondielli , Emmanuele Chersoni , Lucia Passaro , Irene Sucameli , Alessandro Lenci

The advancement of Large Language Models (LLMs) has greatly improved our ability to process complex language. However, accurately detecting logical fallacies remains a significant challenge. This study presents a novel and effective prompt…

Artificial Intelligence · Computer Science 2025-04-01 Jiwon Jeong , Hyeju Jang , Hogun Park

Large language models (LLMs) have demonstrated promising performance on medical benchmarks; however, their ability to perform medical calculations, a crucial aspect of clinical decision-making, remains underexplored and poorly evaluated.…

Computation and Language · Computer Science 2026-02-03 Benlu Wang , Iris Xia , Yifan Zhang , Junda Wang , Feiyun Ouyang , Shuo Han , Arman Cohan , Hong Yu , Zonghai Yao
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