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Nuclei detection and segmentation in hematoxylin and eosin-stained (H&E) tissue images are important clinical tasks and crucial for a wide range of applications. However, it is a challenging task due to nuclei variances in staining and…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Fabian Hörst , Moritz Rempe , Lukas Heine , Constantin Seibold , Julius Keyl , Giulia Baldini , Selma Ugurel , Jens Siveke , Barbara Grünwald , Jan Egger , Jens Kleesiek

Brain tumor classification using MRI images is critical in medical diagnostics, where early and accurate detection significantly impacts patient outcomes. While recent advancements in deep learning (DL), particularly CNNs, have shown…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Priyam Ganguly , Akhilbaran Ghosh

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

Embedding Convolutional Neural Network (CNN) into edge devices for inference is a very challenging task because such lightweight hardware is not born to handle this heavyweight software, which is the common overhead from the modern…

Computer Vision and Pattern Recognition · Computer Science 2020-09-17 Ching-Chen Wang , Ching-Te Chiu , Jheng-Yi Chang

Convolutional neural networks (CNNs) and Transformer-based models are being widely applied in medical image segmentation thanks to their ability to extract high-level features and capture important aspects of the image. However, there is…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Binh-Duong Dinh , Thanh-Thu Nguyen , Thi-Thao Tran , Van-Truong Pham

Nucleus instance segmentation from histopathology images suffers from the extremely laborious and expert-dependent annotation of nucleus instances. As a promising solution to this task, annotation-efficient deep learning paradigms have…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Yu Ming , Zihao Wu , Jie Yang , Danyi Li , Yuan Gao , Changxin Gao , Gui-Song Xia , Yuanqing Li , Li Liang , Jin-Gang Yu

Accurate skin-lesion segmentation remains a key technical challenge for computer-aided diagnosis of skin cancer. Convolutional neural networks, while effective, are constrained by limited receptive fields and thus struggle to model…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Pengyang Yu , Haoquan Wang , Gerard Marks , Tahar Kechadi , Laurence T. Yang , Sahraoui Dhelim , Nyothiri Aung

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

Nuclei segmentation and classification is the first and most crucial step that is utilized for many different microscopy medical analysis applications. However, it suffers from many issues such as the segmentation of small objects,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hussam Azzuni , Muhammad Ridzuan , Min Xu , Mohammad Yaqub

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Martin Weigert , Uwe Schmidt

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Accurate and efficient cell nuclei detection and classification in histopathological Whole Slide Images (WSIs) are pivotal for digital pathology applications. Traditional cell segmentation approaches, while commonly used, are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Oscar Pina , Eduard Dorca , Verónica Vilaplana

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Automatic tissue segmentation and nuclei detection is an important task in pathology, aiding in biomarker extraction and discovery. The panoptic segmentation of nuclei and tissue in advanced melanoma (PUMA) challenge aims to improve tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Negar Shahamiri , Moritz Rempe , Lukas Heine , Jens Kleesiek , Fabian Hörst

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

State-of-the-art (SOTA) Convolutional Neural Networks (CNNs) are criticized for their extensive computational power, long training times, and large datasets. To overcome this limitation, we propose a reasonable network (R-Net), a…

Tissues and Organs · Quantitative Biology 2025-09-23 Rokonozzaman Ayon , Md Taimur Ahad , Bo Song , Yan Li

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang
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