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Latent diffusion models for medical image super-resolution universally inherit variational autoencoders designed for natural photographs. We show that this default choice, not the diffusion architecture, is the dominant constraint on…

In recent years, explainability in machine learning has gained importance. In this context, counterfactual explanation (CE), which is an explanation method that uses examples, has attracted attention. However, it has been pointed out that…

Machine Learning · Computer Science 2025-02-04 Keita Kinjo

Counterfactual explanations (CFEs) are an emerging technique under the umbrella of interpretability of machine learning (ML) models. They provide ``what if'' feedback of the form ``if an input datapoint were $x'$ instead of $x$, then an ML…

Machine Learning · Computer Science 2021-06-16 Sahil Verma , John Dickerson , Keegan Hines

Automated grading of Knee Osteoarthritis (KOA) from radiographs is challenged by significant inter-observer variability and the limited robustness of deep learning models, particularly near critical decision boundaries. To address these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zhe Wang , Yuhua Ru , Aladine Chetouani , Tina Shiang , Fang Chen , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane , William Ewing Palmer , Mohamed Jarraya , Yung Hsin Chen

Internal activations of diffusion models encode rich semantic information, but interpreting such representations remains challenging. While Sparse Autoencoders (SAEs) have shown promise in disentangling latent representations, existing…

Machine Learning · Computer Science 2026-01-23 Zhenghao He , Guangzhi Xiong , Boyang Wang , Sanchit Sinha , Aidong Zhang

Counterfactual explanations (CFEs) guide users on how to adjust inputs to machine learning models to achieve desired outputs. While existing research primarily addresses static scenarios, real-world applications often involve data or model…

Machine Learning · Computer Science 2025-02-11 Ignacy Stępka , Mateusz Lango , Jerzy Stefanowski

Generative AI has received substantial attention in recent years due to its ability to synthesize data that closely resembles the original data source. While Generative Adversarial Networks (GANs) have provided innovative approaches for…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Xuan Xu , Saarthak Kapse , Rajarsi Gupta , Prateek Prasanna

Deep learning classifiers are prone to latching onto dominant confounders present in a dataset rather than on the causal markers associated with the target class, leading to poor generalization and biased predictions. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Nima Fathi , Amar Kumar , Brennan Nichyporuk , Mohammad Havaei , Tal Arbel

Post-hoc explanation methods for machine learning models have been widely used to support decision-making. One of the popular methods is Counterfactual Explanation (CE), also known as Actionable Recourse, which provides a user with a…

Machine Learning · Computer Science 2021-11-10 Kentaro Kanamori , Takuya Takagi , Ken Kobayashi , Yuichi Ike , Kento Uemura , Hiroki Arimura

Counterfactual explanations enhance the interpretability of deep learning models in medical imaging, yet adapting them to 3D CT scans poses challenges due to volumetric complexity and resource demands. We extend the Latent Shift…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Joseph Paul Cohen , Louis Blankemeier , Akshay Chaudhari

Counterfactual explanation is one branch of interpretable machine learning that produces a perturbation sample to change the model's original decision. The generated samples can act as a recommendation for end-users to achieve their desired…

Machine Learning · Computer Science 2023-03-28 Tri Dung Duong , Qian Li , Guandong Xu

Recent work on counterfactual visual explanations has contributed to making artificial intelligence models more explainable by providing visual perturbation to flip the prediction. However, these approaches neglect the causal relationships…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Yiran Qiao , Disheng Liu , Yiren Lu , Yu Yin , Mengnan Du , Jing Ma

Counterfactual explanations have substantially increased in popularity in the past few years as a useful human-centric way of understanding individual black-box model predictions. While several properties desired of high-quality…

Machine Learning · Computer Science 2022-10-14 Shubham Sharma , Alan H. Gee , Jette Henderson , Joydeep Ghosh

Counterfactual explanations for machine learning models are used to find minimal interventions to the feature values such that the model changes the prediction to a different output or a target output. A valid counterfactual explanation…

Machine Learning · Computer Science 2023-03-23 Shravan Kumar Sajja , Sumanta Mukherjee , Satyam Dwivedi

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Machine learning (ML) methods have experienced significant growth in the past decade, yet their practical application in high-impact real-world domains has been hindered by their opacity. When ML methods are responsible for making critical…

Machine Learning · Computer Science 2025-07-11 Xiangyu Sun , Raquel Aoki , Kevin H. Wilson

Vision foundation models (FMs) achieve state-of-the-art performance in medical imaging. However, they encode information in abstract latent representations that clinicians cannot interrogate or verify. The goal of this study is to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Philipp Wesp , Robbie Holland , Vasiliki Sideri-Lampretsa , Sergios Gatidis

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

We leverage diffusion models to study the robustness-performance tradeoff of robust classifiers. Our approach introduces a simple, pretrained diffusion method to generate low-norm counterfactual examples (CEs): semantically altered data…

Machine Learning · Computer Science 2024-04-18 Eric Yeats , Cameron Darwin , Eduardo Ortega , Frank Liu , Hai Li

Estimating counterfactual outcomes over time has the potential to unlock personalized healthcare by assisting decision-makers to answer ''what-iF'' questions. Existing causal inference approaches typically consider regular, discrete-time…

Machine Learning · Computer Science 2022-06-17 Nabeel Seedat , Fergus Imrie , Alexis Bellot , Zhaozhi Qian , Mihaela van der Schaar