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Applications for learning and training have been developed and highlighted as important tools in health education. Despite the several approaches and initiatives, these tools have not been used in an integrated way. The specific skills…

Human-Computer Interaction · Computer Science 2019-06-05 Thaise Costa , Liliane Machado , Ana Maria Gondim Valença , Marco Winckler , Ronei Moraes

In the emergency department (ED), patients undergo triage and multiple laboratory tests before diagnosis. This time-consuming process causes ED crowding which impacts patient mortality, medical errors, staff burnout, etc. This work proposes…

Computation and Language · Computer Science 2024-05-29 Liwen Sun , Abhineet Agarwal , Aaron Kornblith , Bin Yu , Chenyan Xiong

Molecular optimization is a central task in drug discovery that requires precise structural reasoning and domain knowledge. While large language models (LLMs) have shown promise in generating high-level editing intentions in natural…

Machine Learning · Computer Science 2025-10-17 Wenyu Zhu , Chengzhu Li , Xiaohe Tian , Yifan Wang , Yinjun Jia , Jianhui Wang , Bowen Gao , Ya-Qin Zhang , Wei-Ying Ma , Yanyan Lan

Phase I early-phase clinical studies aim at investigating the safety and the underlying dose-toxicity relationship of a drug or combination. While little may still be known about the compound's properties, it is crucial to consider…

Methodology · Statistics 2022-09-13 Christian Röver , Moreno Ursino , Tim Friede , Sarah Zohar

We introduce MMaDA, a novel class of multimodal diffusion foundation models designed to achieve superior performance across diverse domains such as textual reasoning, multimodal understanding, and text-to-image generation. The approach is…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Ling Yang , Ye Tian , Bowen Li , Xinchen Zhang , Ke Shen , Yunhai Tong , Mengdi Wang

In critical care settings such as the Intensive Care Unit, clinicians face the complex challenge of balancing conflicting objectives, primarily maximizing patient survival while minimizing resource utilization (e.g., length of stay).…

Machine Learning · Computer Science 2025-12-10 Aryaman Bansal , Divya Sharma

This paper discusses how ophthalmologists often rely on multimodal data to improve diagnostic accuracy. However, complete multimodal data is rare in real-world applications due to a lack of medical equipment and concerns about data privacy.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Xinkun Wang , Yifang Wang , Senwei Liang , Feilong Tang , Chengzhi Liu , Ming Hu , Chao Hu , Junjun He , Zongyuan Ge , Imran Razzak

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Background. The DURATIONS design has been recently proposed as a practical alternative to a standard two-arm non-inferiority design when the goal is to optimise some continuous aspect of treatment administration, e.g. duration or frequency,…

Applications · Statistics 2023-04-20 Matteo Quartagno , Ehsan Ghorani , Tim P Morris , Michael J Seckl , Mahesh KB Parmar

Medical decision-support and advising systems are critical for emergency physicians to quickly and accurately assess patients' conditions and make diagnosis. Artificial Intelligence (AI) has emerged as a transformative force in healthcare…

Medical order extraction is essential for structuring actionable clinical information, supporting decision-making, and enabling downstream applications such as documentation and workflow automation. Orders may be embedded in diverse…

Computation and Language · Computer Science 2025-10-14 A H M Rezaul Karim , Ozlem Uzuner

Masked diffusion language models (MDLMs) have recently emerged as a promising alternative to autoregressive (AR) language models, offering properties such as parallel decoding, flexible generation orders, and the potential for fewer…

Computation and Language · Computer Science 2025-09-30 Jingyi Yang , Guanxu Chen , Xuhao Hu , Jing Shao

Reinforcement learning (RL) for large language models (LLMs) has shown strong performance in single-turn tasks, but extending it to multi-turn interaction remains challenging due to sparse rewards and poor per-turn credit assignment. In…

Computation and Language · Computer Science 2026-05-06 Naifan Zhang , Ruihan Sun , Jinwei Su , Hengjie Yang , Zhengyuan Pan , Zhaohan Chen , Xiaofan Zhang

Prediction of medical codes from clinical notes is both a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort spent by…

Computation and Language · Computer Science 2021-07-23 Byung-Hak Kim , Varun Ganapathi

Video-LLMs are increasingly deployed in safety-critical applications but are vulnerable to Energy-Latency Attacks (ELAs) that exhaust computational resources. Current image-centric methods fail because temporal aggregation mechanisms dilute…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Duoxun Tang , Dasen Dai , Jiyao Wang , Xiao Yang , Jianyu Wang , Siqi Cai

A meaningful understanding of clinical protocols and patient pathways helps improve healthcare outcomes. Electronic health records (EHR) reflect real-world treatment behaviours that are used to enhance healthcare management but present…

Machine Learning · Computer Science 2021-10-05 Adrian Caruana , Madhushi Bandara , Daniel Catchpoole , Paul J Kennedy

A key task in ML is to optimize models at various stages, e.g. by choosing hyperparameters or picking a stopping point. A traditional ML approach is to use validation loss, i.e. to apply the training loss function on a validation set to…

Machine Learning · Computer Science 2026-01-23 Charles B. Delahunt , Courosh Mehanian , Daniel E. Shea , Matthew P. Horning

Brain-machine interfaces (BMIs) are expanding beyond clinical settings thanks to advances in hardware and algorithms. However, they still face challenges in user-friendliness and signal variability. Classification models need periodic…

Signal Processing · Electrical Eng. & Systems 2024-09-24 Lan Mei , Cristian Cioflan , Thorir Mar Ingolfsson , Victor Kartsch , Andrea Cossettini , Xiaying Wang , Luca Benini

This article presents an experiment focused on optimizing the MLOps (Machine Learning Operations) process, a crucial aspect of efficiently implementing machine learning projects. The objective is to identify patterns and insights to enhance…

Software Engineering · Computer Science 2023-07-26 Awadelrahman M. A. Ahmed

The demand of transparency of clinical research results, the need of accelerating the process of transferring innovation in the daily medical practice as well as assuring patient safety and product efficacy make it necessary to extend the…

Software Engineering · Computer Science 2013-01-10 Daniela Luzi , Fabrizio Pecoraro