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Related papers: BioRAG: A RAG-LLM Framework for Biological Questio…

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We present BioRAGent, an interactive web-based retrieval-augmented generation (RAG) system for biomedical question answering. The system uses large language models (LLMs) for query expansion, snippet extraction, and answer generation while…

Computation and Language · Computer Science 2024-12-18 Samy Ateia , Udo Kruschwitz

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Real-world live retrieval-augmented generation (RAG) systems face significant challenges when processing user queries that are often noisy, ambiguous, and contain multiple intents. While RAG enhances large language models (LLMs) with…

Computation and Language · Computer Science 2025-06-27 Guanting Dong , Xiaoxi Li , Yuyao Zhang , Mengjie Deng

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

Retrieval-augmented generation (RAG) enhances the question-answering (QA) abilities of large language models (LLMs) by integrating external knowledge. However, adapting general-purpose RAG systems to specialized fields such as science and…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hui Liu , Sreyashi Nag , Zhenwei Dai , Yaochen Xie , Xianfeng Tang , Chen Luo , Yang Li , Joyce C. Ho , Carl Yang , Qi He

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Recent advancements in retrieval-augmented generation (RAG) have significantly enhanced the ability of large language models (LLMs) to perform complex question-answering (QA) tasks. In this paper, we introduce MedBioRAG, a…

Computation and Language · Computer Science 2025-12-15 Seonok Kim

Retrieval augmented generation (RAG) has shown great power in improving Large Language Models (LLMs). However, most existing RAG-based LLMs are dedicated to retrieving single modality information, mainly text; while for many real-world…

Computation and Language · Computer Science 2025-06-09 Saptarshi Sengupta , Shuhua Yang , Paul Kwong Yu , Fali Wang , Suhang Wang

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

Retrieval-Augmented Generation (RAG) systems enhance large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user needs. However, existing RAG systems…

Information Retrieval · Computer Science 2025-04-29 Zirui Guo , Lianghao Xia , Yanhua Yu , Tu Ao , Chao Huang

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

Computation and Language · Computer Science 2025-02-06 Seonok Kim

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Protein-Text Question Answering (QA) is crucial for interpreting biological sequences through natural language. The integration of Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) that efficiently leverages biological…

Information Retrieval · Computer Science 2026-05-19 Li Ding , Duanyu Feng , Chen Huang , Yangshuai Wang , Yang Li , Wenqiang Lei , See-Kiong Ng

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang
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