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Multiple hypothesis testing problems arise naturally in science. In this paper, we introduce the new Fast Closed Testing (FACT) method for multiple testing, controlling the family-wise error rate. This error rate is state of the art in many…

Methodology · Statistics 2020-01-22 Edgar Dobriban

We provide a theoretical framework to understand how widely used measures of choice difficulty relate. In a binary-option Bayesian expected-utility framework, we show that three measures of difficulty, (i) understanding (ex-ante value),…

Theoretical Economics · Economics 2026-04-30 Chris Chambers , Yusufcan Masatolioglu , Paulo Natenzon , Collin Raymond

Statistical dependence between hypotheses poses a significant challenge to the stability of large scale multiple hypotheses testing. Ignoring it often results in an unacceptably large spread in the false positive proportion even though the…

Methodology · Statistics 2018-10-15 Sairam Rayaprolu , Zhiyi Chi

All proper scoring rules incentivize an expert to predict \emph{accurately} (report their true estimate), but not all proper scoring rules equally incentivize \emph{precision}. Rather than treating the expert's belief as exogenously given,…

Computer Science and Game Theory · Computer Science 2021-06-01 Eric Neyman , Georgy Noarov , S. Matthew Weinberg

This paper addresses the challenge of identifying a minimal subset of discrete, independent variables that best predicts a binary class. We propose an efficient iterative method that sequentially selects variables based on which one…

Computation · Statistics 2025-11-03 María del Carmen Romero , Mariana del Fresno , Alejandro Clausse

A key trait of stochastic optimizers is that multiple runs of the same optimizer in attempting to solve the same problem can produce different results. As a result, their performance is evaluated over several repeats, or runs, on the…

Machine Learning · Computer Science 2026-05-18 Moslem Noori , Elisabetta Valiante , Thomas Van Vaerenbergh , Masoud Mohseni , Ignacio Rozada

This paper tackles the challenge of performing multiple quantile regressions across different quantile levels and the associated problem of controlling the familywise error rate, an issue that is generally overlooked in practice. We propose…

Methodology · Statistics 2026-04-10 Riccardo De Santis , Anna Vesely , Angela Andreella

Signal processing makes extensive use of point estimators and accompanying error bounds. These work well up until the likelihood function has two or more high peaks. When it is important for an estimator to remain reliable, it becomes…

Methodology · Statistics 2025-03-04 Ning Xu , Christopher M. Foster , Jonathan H. Manton

Tests based on heteroskedasticity robust standard errors are an important technique in econometric practice. Choosing the right critical value, however, is not simple at all: conventional critical values based on asymptotics often lead to…

Statistics Theory · Mathematics 2025-05-07 Benedikt M. Pötscher , David Preinerstorfer

Large language models (LLMs) achieve strong reasoning performance by allocating substantial computation at inference time, often generating long and verbose reasoning traces. While recent work on efficient reasoning reduces this overhead…

Computation and Language · Computer Science 2026-04-28 Han Wang , Xiaodong Yu , Jialian Wu , Jiang Liu , Ximeng Sun , Mohit Bansal , Zicheng Liu

In this paper we use e-values in the context of multiple hypothesis testing assuming that the base tests produce independent, or sequential, e-values. Our simulation and empirical studies and theoretical considerations suggest that, under…

Methodology · Statistics 2024-08-14 Vladimir Vovk , Ruodu Wang

Classical and more recent tests for detecting distributional changes in multivariate time series often lack power against alternatives that involve changes in the cross-sectional dependence structure. To be able to detect such changes…

Statistics Theory · Mathematics 2014-09-16 Axel Bücher , Ivan Kojadinovic , Tom Rohmer , Johan Segers

Multiple hypothesis testing (MHT) frequently arises in scientific inquiries, and concurrent testing of multiple hypotheses inflates the risk of Type-I errors or false positives, rendering MHT corrections essential. This paper addresses MHT…

We propose modified frequentist definition for the determination of confidence intervals for the case of Poisson statistics. Namely, we require that 1-\beta' \geq \sum_{n=o}^{n_{obs}+k} P(n|\lambda) \geq \alpha'. We show that this…

Data Analysis, Statistics and Probability · Physics 2012-06-19 Sergey Bitioukov , Nikolai Krasnikov

There has been a misconception that only one type of error rate control is necessary in clinical trials, leading to debates over whether to prioritize Familywise Error Rate (FWER) or False Discovery Rate (FDR). This misconception has led to…

Methodology · Statistics 2026-03-26 Xinping Cui , Emily Ouyang , Yi Liu , Jingjing Yan Schneider , Hong Tian , Bushi Wang , Jason C. Hsu

The method of obtaining confidence intervals on a subset of the total number of parameters (p) of a model used for fitting X-ray spectra is to perturb the best-fitting model until, for each parameter, a range is found for which the change…

Astrophysics · Physics 2009-10-30 T. Yaqoob

Much of science is (rightly or wrongly) driven by hypothesis testing. Even in situations where the hypothesis testing paradigm is correct, the common practice of basing inferences solely on p-values has been under intense criticism for over…

Methodology · Statistics 2015-12-31 M. J. Bayarri , Daniel J. Benjamin , James O. Berger , Thomas M. Sellke

Calibration, the practice of choosing the parameters of a structural model to match certain empirical moments, can be viewed as minimum distance estimation. Existing standard error formulas for such estimators require a consistent estimate…

Econometrics · Economics 2024-06-19 Matthew D. Cocci , Mikkel Plagborg-Møller

Simultaneous tests of superiority and non-inferiority hypotheses on multiple endpoints are often performed in clinical trials to demonstrate that a new treatment is superior over a control on at least one endpoint and non-inferior on the…

Methodology · Statistics 2023-10-02 Wenfeng Chen , Naiqing Zhao , Guoyou Qin , Jie Chen

This article explains, and discusses the merits of, three approaches for analyzing the certainty with which statistical results can be extrapolated beyond the data gathered. Sometimes it may be possible to use more than one of these…

Methodology · Statistics 2016-10-03 Michael Wood
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