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Related papers: Propagation of Enzyme-driven Active Fluctuations i…

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Spontaneous persistent motions driven by active processes play a central role to maintain the living cells far from equilibrium. In the majority of the research works, the steady state dynamics of an active system has been described in…

Statistical Mechanics · Physics 2020-07-01 Subhasish Chaki , Rajarshi Chakrabarti

Many active particles are embedded in environments that exhibit viscoelastic properties. An important class of such media lacks a single characteristic relaxation timescale when subjected to a time-dependent stress. Rather, the stress…

Soft Condensed Matter · Physics 2025-12-24 David Santiago Quevedo , Monica Conte , Marjolein Dijkstra , Cristiane Morais Smith

Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…

Soft Condensed Matter · Physics 2025-08-27 Henry Alston , Raphael Voituriez , Thibault Bertrand

Molecular agitation more rapid than thermal Brownian motion is reported for cellular environments, motor proteins, synthetic molecular motors, enzymes, and common chemical reactions, yet that chemical activity couples to molecular motion…

Soft Condensed Matter · Physics 2022-06-08 Ah-Young Jee , Tsvi Tlusty , Steve Granick

We use molecular dynamics simulations to investigate the tracer diffusion in a sea of polymers with specific binding zones for the tracer. These binding zones act as traps. Our simulations show that the tracer can undergo normal yet…

Soft Condensed Matter · Physics 2016-09-22 Nairhita Samanta , Rajarshi Chakrabarti

Diffusion of a two component fluid is studied in the framework of differential equations, but where these equations are systematically derived from a well-defined microscopic model. The model has a finite carrying capacity imposed upon it…

Statistical Mechanics · Physics 2015-06-04 D. Fanelli , A. J. McKane , G. Pompili , B. Tiribilli , M. Vassalli , T. Biancalani

Macromolecular crowding in living biological cells effects subdiffusion of larger biomolecules such as proteins and enzymes. Mimicking this subdiffusion in terms of random walks on a critical percolation cluster, we here present a case…

Subcellular Processes · Quantitative Biology 2012-03-09 Leila Esmaeili Sereshki , Michael A. Lomholt , Ralf Metzler

In addition to enabling movement towards environments with favourable living conditions, swimming by microorganisms has also been linked to enhanced mixing and improved nutrient uptake by their populations. Experimental studies have shown…

Fluid Dynamics · Physics 2017-11-07 Blaise Delmotte , Eric E Keaveny , Eric Climent , Franck Plouraboué

We study the induced dynamics of an inertial tracer particle elastically coupled to passive or active Brownian particles. We integrate out the environment degrees of freedom to obtain generalized Langevin equation for the tracer dynamics in…

Statistical Mechanics · Physics 2023-08-16 Ion Santra

Enzymes have been recently proposed to have mechanical activity associated with their chemical activity. In a number of recent studies, it has been reported that enzymes undergo enhanced diffusion in the presence of their corresponding…

Biological Physics · Physics 2021-04-07 Jaime Agudo-Canalejo , Tunrayo Adeleke-Larodo , Pierre Illien , Ramin Golestanian

We study the dynamics of an ideal polymer chain in a crowded, viscoelastic medium and in the presence of active forces. The motion of the centre of mass and of individual monomers is calculated. On time scales that are comparable to the…

Soft Condensed Matter · Physics 2015-12-23 Hans Vandebroek , Carlo Vanderzande

With the use of the "two-fluid model", we discuss anomalous diffusion induced by active force dipoles in viscoelastic media. Active force dipoles, such as proteins and bacteria, generate non-thermal fluctuating flows that lead to a…

Soft Condensed Matter · Physics 2017-03-29 Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

Soft Condensed Matter · Physics 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

We present a multiscale approach to model diffusion in a crowded environment and its effect on the reaction rates. Diffusion in biological systems is often modeled by a discrete space jump process in order to capture the inherent noise of…

Subcellular Processes · Quantitative Biology 2016-03-18 Lina Meinecke

Mechanochemically active enzymes change their shapes within every turnover cycle. Therefore, they induce circulating flows in the solvent around them and behave as oscillating hydrodynamic force dipoles. Because of non-equilibrium…

Soft Condensed Matter · Physics 2021-12-28 Yuto Hosaka , Shigeyuki Komura , Alexander S. Mikhailov

Using granular experiments and computer simulations, we investigate the long-time diffusion of active tracers in a broad class of complex media composed of frozen obstacles of diverse structures. By introducing a dimensionless persistence…

Soft Condensed Matter · Physics 2025-05-06 Qun Zhang , Yuxin Tian , Xue Zhang , Xiaoting Yu , Hongwei Zhu , Ning Zheng , Luhui Ning , Ran Ni , Mingcheng Yang , Peng Liu

Channels are fundamental building blocks from biophysics to soft robotics, often used to transport or separate solutes. As solute particles inevitably transverse between streamlines along the channel by molecular diffusion, the effective…

Soft Condensed Matter · Physics 2020-02-10 Sophie Marbach , Karen Alim

A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe this "age-old" dynamic disorder phenomenon directly. However,…

Biomolecules · Quantitative Biology 2009-11-10 Zhanghan Wu , Vlad Elgart , Hong Qian , Jianhua Xing

We experimentally, numerically and analytically explore the diffusive transport of active colloidal particles with sensory delay, navigating motility landscapes in which the self-propulsion speed depends on space. We show how the transport…

Statistical Mechanics · Physics 2026-04-29 Adrià Garcés , Ueli Töpfer , Lucio Isa , Demian Levis , Ignacio Pagonabarraga

Active transport of biomolecules assisted by motor proteins is imperative for the proper functioning of cellular activities. Inspired by the diffusion of active agents in crowded cellular channels, we computationally investigate the…

Soft Condensed Matter · Physics 2022-01-19 Rajiblochan Sahoo , Ligesh Theeyancheri , Rajarshi Chakrabarti