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Related papers: Integrating spatially-resolved transcriptomics dat…

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Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Konstantin Hemker , Andrew H. Song , Cristina Almagro-Pérez , Guillaume Jaume , Sophia J. Wagner , Anurag Vaidya , Nikola Simidjievski , Mateja Jamnik , Faisal Mahmood

Single-cell spatial transcriptomics (ST) offers a unique approach to measuring gene expression profiles and spatial cell locations simultaneously. However, most existing ST methods assume that cells in closer spatial proximity exhibit more…

Genomics · Quantitative Biology 2025-06-10 Xiongtao Xiao , Xiaofeng Chen , Feiyan Jiang , Songming Zhang , Wenming Cao , Cheng Tan , Zhangyang Gao , Zhongshan Li

Spatially resolved transcriptomics is a fast-developing set of technologies that enables the measurement of localized gene expression across spatial locations in a sample. Detecting spatially varying genes is critical for analyzing such…

Applications · Statistics 2026-04-22 Pritam Dey , Rajarshi Guhaniyogi , Yang Ni , Bani K. Mallick

Improving the image resolution and acquisition speed of magnetic resonance imaging (MRI) is a challenging problem. There are mainly two strategies dealing with the speed-resolution trade-off: (1) $k$-space undersampling with high-resolution…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wenqi Huang , Sen Jia , Ziwen Ke , Zhuo-Xu Cui , Jing Cheng , Yanjie Zhu , Dong Liang

Remote sensing images and techniques are powerful tools to investigate earth surface. Data quality is the key to enhance remote sensing applications and obtaining a clear and noise-free set of data is very difficult in most situations due…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Hessah Albanwan , Rongjun Qin

Spatial Transcriptomics (ST) allows a high-resolution measurement of RNA sequence abundance by systematically connecting cell morphology depicted in Hematoxylin and Eosin (H&E) stained histology images to spatially resolved gene…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Sichen Zhu , Yuchen Zhu , Molei Tao , Peng Qiu

Spatially resolved transcriptomics represents a significant advancement in single-cell analysis by offering both gene expression data and their corresponding physical locations. However, this high degree of spatial resolution entails a…

Genomics · Quantitative Biology 2024-03-19 Xiaoyu Li , Wenwen Min , Shunfang Wang , Changmiao Wang , Taosheng Xu

Spatial transcriptomics enables genome-wide expression analysis within native tissue context, yet identifying spatial domains remains challenging due to complex gene-spatial interactions. Existing methods typically process spatial and…

Machine Learning · Computer Science 2025-12-19 Jianping Mei , Siqi Ai , Ye Yuan

Recently, experiments have been reported where researchers were able to perform high dynamic range (HDR) tomography in a heuristic fashion, by fusing multiple tomographic projections. This approach to HDR tomography has been inspired by HDR…

Information Theory · Computer Science 2021-05-11 Matthias Beckmann , Ayush Bhandari , Felix Krahmer

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

With the advancement of GPS and remote sensing technologies, large amounts of geospatial and spatiotemporal data are being collected from various domains, driving the need for effective and efficient prediction methods. Given spatial data…

Machine Learning · Computer Science 2020-12-25 Zhe Jiang

Topological data analysis (TDA) has emerged as one of the most promising techniques to reconstruct the unknown shapes of high-dimensional spaces from observed data samples. TDA, thus, yields key shape descriptors in the form of persistent…

Machine Learning · Statistics 2017-11-15 Wei Guo , Krithika Manohar , Steven L. Brunton , Ashis G. Banerjee

High-resolution (HR) magnetic resonance imaging (MRI) is crucial for many clinical and research applications. However, achieving it remains costly and constrained by technical trade-offs and experimental limitations. Super-resolution (SR)…

This comprehensive review examines electrical and seismic refraction methods, emphasizing their advanced applications in electrical resistivity tomography (ERT) and seismic refraction tomography (SRT). These techniques are crucial for…

Geophysics · Physics 2025-07-23 Adedibu Sunny Akingboye

Spatial transcriptomics (ST) enables mapping gene expression with spatial context but is severely affected by high sparsity and technical noise, which conceals true biological signals and hinders downstream analyses. To address these…

Machine Learning · Computer Science 2026-03-10 Sayeem Bin Zaman , Fahim Hafiz , Riasat Azim

Path planning in high-dimensional spaces poses significant challenges, particularly in achieving both time efficiency and a fair success rate. To address these issues, we introduce a novel path-planning algorithm, Zonal RL-RRT, that…

Robotics · Computer Science 2024-11-01 AmirMohammad Tahmasbi , MohammadSaleh Faghfoorian , Saeed Khodaygan , Aniket Bera

A new statistical model designed for regression analysis with a sparse design matrix is proposed. This new model utilizes the positions of the limited non-zero elements in the design matrix to decompose the regression model into…

Applications · Statistics 2022-01-17 Hsien-Wei Chen

Image translation for change detection or classification in bi-temporal remote sensing images is unique. Although it can acquire paired images, it is still unsupervised. Moreover, strict semantic preservation in translation is always needed…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Sheng Fang , Kaiyu Li , Zhe Li , Jianli Zhao , Xingli Zhang

Gene expression profiling technologies have been used in various applications such as cancer biology. The development of gene expression profiling has expanded the scope of target discovery in transcriptomic studies, and each technology…

Genomics · Quantitative Biology 2023-01-10 Hyeongseon Jeon , Juan Xie , Yeseul Jeon , Kyeong Joo Jung , Arkobrato Gupta , Won Chang , Dongjun Chung

In the analysis of spatially resolved transcriptomics data, detecting spatially variable genes (SVGs) is crucial. Numerous computational methods exist, but varying SVG definitions and methodologies lead to incomparable results. We review 33…

Quantitative Methods · Quantitative Biology 2024-10-04 Guanao Yan , Shuo Harper Hua , Jingyi Jessica Li