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We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an…

Molecular Networks · Quantitative Biology 2014-08-12 Edwin Wang , Naif Zaman , Shauna Mcgee , Jean-Sébastien Milanese , Ali Masoudi-Nejad , Maureen O'Connor

Recently, deep learning methods have achieved state-of-the-art performance in many medical image segmentation tasks. Many of these are based on convolutional neural networks (CNNs). For such methods, the encoder is the key part for global…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hao Li , Dewei Hu , Han Liu , Jiacheng Wang , Ipek Oguz

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Convolutional Neural Networks (CNNs) have reigned for a decade as the de facto approach to automated medical image diagnosis. Recently, vision transformers (ViTs) have appeared as a competitive alternative to CNNs, yielding similar levels…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Christos Matsoukas , Johan Fredin Haslum , Magnus Söderberg , Kevin Smith

With the wide and deep adoption of deep learning models in real applications, there is an increasing need to model and learn the representations of the neural networks themselves. These models can be used to estimate attributes of different…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Yun Yi , Haokui Zhang , Wenze Hu , Nannan Wang , Xiaoyu Wang

The hybrid architecture of convolutional neural networks (CNNs) and Transformer are very popular for medical image segmentation. However, it suffers from two challenges. First, although a CNNs branch can capture the local image features…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Tao Lei , Rui Sun , Xuan Wang , Yingbo Wang , Xi He , Asoke Nandi

Neural methods of molecule property prediction require efficient encoding of structure and property relationship to be accurate. Recent work using graph algorithms shows limited generalization in the latent molecule encoding space. We build…

Quantitative Methods · Quantitative Biology 2020-11-26 Prateeth Nayak , Andrew Silberfarb , Ran Chen , Tulay Muezzinoglu , John Byrnes

Transformers have dominated the field of natural language processing, and recently impacted the computer vision area. In the field of medical image analysis, Transformers have also been successfully applied to full-stack clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Kelei He , Chen Gan , Zhuoyuan Li , Islem Rekik , Zihao Yin , Wen Ji , Yang Gao , Qian Wang , Junfeng Zhang , Dinggang Shen

Medical image segmentation is an essential prerequisite for developing healthcare systems, especially for disease diagnosis and treatment planning. On various medical image segmentation tasks, the u-shaped architecture, also known as U-Net,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jieneng Chen , Yongyi Lu , Qihang Yu , Xiangde Luo , Ehsan Adeli , Yan Wang , Le Lu , Alan L. Yuille , Yuyin Zhou

This study proposed a hybrid model of a convolutional neural network (CNN) and a Transformer to predict and diagnose heart disease. Based on CNN's strength in detecting local features and the Transformer's high capacity in sensing global…

Machine Learning · Computer Science 2025-03-05 Ran Hao , Yanlin Xiang , Junliang Du , Qingyuan He , Jiacheng Hu , Ting Xu

High-resolution images are preferable in medical imaging domain as they significantly improve the diagnostic capability of the underlying method. In particular, high resolution helps substantially in improving automatic image segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-03 Muhammad Hamza Sharif , Dmitry Demidov , Asif Hanif , Mohammad Yaqub , Min Xu

Characterizing non-coding variant function remains an important challenge in human genetics. Genomic deep learning models have emerged as a promising approach to enable in silico prediction of variant effects. These include supervised…

Genomics · Quantitative Biology 2025-11-25 Pooja Kathail , Ayesha Bajwa , Nilah M. Ioannidis

Genomic selection (GS), as a critical crop breeding strategy, plays a key role in enhancing food production and addressing the global hunger crisis. The predominant approaches in GS currently revolve around employing statistical methods for…

Machine Learning · Computer Science 2024-06-25 Renqi Chen , Wenwei Han , Haohao Zhang , Haoyang Su , Zhefan Wang , Xiaolei Liu , Hao Jiang , Wanli Ouyang , Nanqing Dong

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

Deep neural networks have been widely used in medical image analysis and medical image segmentation is one of the most important tasks. U-shaped neural networks with encoder-decoder are prevailing and have succeeded greatly in various…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Juntao Jiang , Xiyu Chen , Guanzhong Tian , Yong Liu

Multi-modal skin lesion diagnosis (MSLD) has achieved remarkable success by modern computer-aided diagnosis (CAD) technology based on deep convolutions. However, the information aggregation across modalities in MSLD remains challenging due…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yilan Zhang , Fengying Xie , Jianqi Chen

Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Hosein Barzekar , Yash Patel , Ling Tong , Zeyun Yu

Interactive image segmentation aims to segment the target from the background with the manual guidance, which takes as input multimodal data such as images, clicks, scribbles, and bounding boxes. Recently, vision transformers have achieved…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Kun Li , George Vosselman , Michael Ying Yang

Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jihoon Cho , Xiaofeng Liu , Fangxu Xing , Jinsong Ouyang , Georges El Fakhri , Jinah Park , Jonghye Woo

Obtaining effective representations of DNA sequences is crucial for genome analysis. Metagenomic binning, for instance, relies on genome representations to cluster complex mixtures of DNA fragments from biological samples with the aim of…

Machine Learning · Computer Science 2024-11-05 Abdulkadir Celikkanat , Andres R. Masegosa , Thomas D. Nielsen
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