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Image-guided interventions are saving the lives of a large number of patients where the image registration problem should indeed be considered as the most complex and complicated issue to be tackled. On the other hand, the recently huge…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Hamid Reza Boveiri , Raouf Khayami , Reza Javidan , Ali Reza MehdiZadeh

Image registration is an essential technique for the analysis of Computed Tomography (CT) images in clinical practice. However, existing methodologies are predominantly tailored to a specific organ of interest and often exhibit lower…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Xuan Loc Pham , Mathias Prokop , Bram van Ginneken , Alessa Hering

Medical image challenges have played a transformative role in advancing the field, catalyzing innovation and establishing new performance benchmarks. Image registration, a foundational task in neuroimaging, has similarly advanced through…

Multimodal groupwise registration aligns internal structures in a group of medical images. Current approaches to this problem involve developing similarity measures over the joint intensity profile of all images, which may be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xin Wang , Xinzhe Luo , Xiahai Zhuang

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

Deep neural networks are increasingly used for pair-wise image registration. We propose to extend current learning-based image registration to allow simultaneous registration of multiple images. To achieve this, we build upon the pair-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Tycho F. A. van der Ouderaa , Ivana Išgum , Wouter B. Veldhuis , Bob D. de Vos

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Objective: Deep learning-based deformable image registration has achieved strong accuracy, but remains sensitive to variations in input image characteristics such as artifacts, field-of-view mismatch, or modality difference. We aim to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yihao Liu , Junyu Chen , Lianrui Zuo , Shuwen Wei , Brian D. Boyd , Carmen Andreescu , Olusola Ajilore , Warren D. Taylor , Aaron Carass , Bennett A. Landman

Multi-modality is widely used in medical imaging, because it can provide multiinformation about a target (tumor, organ or tissue). Segmentation using multimodality consists of fusing multi-information to improve the segmentation. Recently,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Tongxue Zhou , Su Ruan , Stéphane Canu

This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

This document outlines a tutorial to get started with medical image registration using the open-source package DeepReg. The basic concepts of medical image registration are discussed, linking classical methods to newer methods using deep…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 N. Montana Brown , Y. Fu , S. U. Saeed , A. Casamitjana , Z. M. C. Baum , R. Delaunay , Q. Yang , A. Grimwood , Z. Min , E. Bonmati , T. Vercauteren , M. J. Clarkson , Y. Hu

Deformable image registration plays a critical role in various tasks of medical image analysis. A successful registration algorithm, either derived from conventional energy optimization or deep networks requires tremendous efforts from…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Xin Fan , Zi Li , Ziyang Li , Xiaolin Wang , Risheng Liu , Zhongxuan Luo , Hao Huang

Multimodal image registration is a very challenging problem for deep learning approaches. Most current work focuses on either supervised learning that requires labelled training scans and may yield models that bias towards annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Mattias P Heinrich , Lasse Hansen

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

We study the problem of registration for medical CT images from a novel perspective -- the sensitivity to degree of deformations in CT images. Although some learning-based methods have shown success in terms of average accuracy, their…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Xinyu Zhao , Sa Huang , Wei Pang , You Zhou

Multi-modality medical images can provide relevant or complementary information for a target (organ, tumor or tissue). Registering multi-modality images to a common space can fuse these comprehensive information, and bring convenience for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Wangbin Ding , Lei Li , Xiahai Zhuang , Liqin Huang

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Recent advancements in deep learning have significantly revolutionized the field of clinical diagnosis and treatment, offering novel approaches to improve diagnostic precision and treatment efficacy across diverse clinical domains, thus…

Artificial Intelligence · Computer Science 2024-12-04 Kai Sun , Siyan Xue , Fuchun Sun , Haoran Sun , Yu Luo , Ling Wang , Siyuan Wang , Na Guo , Lei Liu , Tian Zhao , Xinzhou Wang , Lei Yang , Shuo Jin , Jun Yan , Jiahong Dong

Objective: Deformable brain MR image registration is challenging due to large inter-subject anatomical variation. For example, the highly complex cortical folding pattern makes it hard to accurately align corresponding cortical structures…

Computer Vision and Pattern Recognition · Computer Science 2019-02-07 Dongming Wei , Zhengwang Wu , Gang Li , Xiaohuan Cao , Dinggang Shen , Qian Wang