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Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Intracellular lasers are emerging as powerful biosensors for multiplexed tracking and precision sensing of cells and their microenvironment. This sensing capacity is enabled by quantifying their narrow-linewidth emission spectra, which is…

We develop a device model for pixelless converters of far/mid-infrared radiation (FIR/MIR) images into near-infrared/visible (NIR/VIR) images. These converters use polycrystalline graphene layers (PGLs) immersed in the van der Waals (vdW)…

Mesoscale and Nanoscale Physics · Physics 2018-02-14 V. Ryzhii , M. S. Shur , M. Ryzhii , V. E. Karasik , T. Otsuj

Liquids and granular media are pervasive throughout human environments. Their free-flowing nature causes people to constrain them into containers. We do so with thousands of different types of containers made out of different materials with…

We use photothermal induced resonance (PTIR) imaging and spectroscopy, in resonant and non-resonant mode, to study the cytoplasmic membrane and surface of intact cells. Non-resonant PTIR images apparently provide rich details of the cell…

Applied Physics · Physics 2021-01-27 Luca Quaroni

Frequency upconversion technique offers an appealing approach for sensitive mid-infrared (MIR) imaging at room temperature. However, the spatial resolution of the upconversion imager has been notoriously restricted by the limited transverse…

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

High-speed mid-infrared (MIR) videography constitutes an enabling tool to monitor and analyze various dynamics in scientific research and industrial applications, such as combustion diagnostics, explosion reactions, photosynthetic tracking,…

Optics · Physics 2026-05-28 Ruiyang Qin , Kun Huang , Min Peng , Jianan Fang , Ben Sun , Zhengru Guo , Heping Zeng

Hyperspectral images, which record the electromagnetic spectrum for a pixel in the image of a scene, often store hundreds of channels per pixel and contain an order of magnitude more information than a similarly-sized RBG color image.…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Shima Rezasoltani , Faisal Z. Qureshi

We experimentally demonstrate imaging in the longwave-infrared (LWIR) spectral band (8um to 12um) using a single polymer flat lens based upon multi-level diffractive optics. The device thickness is only 10{\mu}m, and chromatic aberrations…

Hyperspectral image (HSI) super-resolution without additional auxiliary image remains a constant challenge due to its high-dimensional spectral patterns, where learning an effective spatial and spectral representation is a fundamental…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Kaiwei Zhang

This thesis investigates the application of near-infrared hyperspectral imaging (NIR-HSI) for food quality analysis. The investigation is conducted through four studies operating with five research hypotheses. For several analyses, the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ole-Christian Galbo Engstrøm

Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip…

Nonlinear interferometers allow spectroscopy in the mid-infrared range by detecting correlated visible light, for which non-cooled detectors with higher specific detectivity and lower dark count rates are available. We present a new…

Optics · Physics 2020-03-19 Chiara Lindner , Sebastian Wolf , Jens Kießling , Frank Kühnemann

Hyperspectral imaging measures the amount of electromagnetic energy across the instantaneous field of view at a very high resolution in hundreds or thousands of spectral channels. This enables objects to be detected and the identification…

Image and Video Processing · Electrical Eng. & Systems 2021-03-15 Lina Zhuang , Lianru Gao , Bing Zhang , Xiyou Fu , Jose M. Bioucas-Dias

Hyperspectral imagery (HSI) is an established technique with an array of applications, but its use is limited due to both practical and technical issues associated with spectral devices. The goal of the ICASSP 2024 'Hyper-Skin' Challenge is…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Wojciech Czaja , Jeremiah Emidih , Brandon Kolstoe , Richard G. Spencer

Mid-infrared spectroscopy probes molecular vibrations to identify chemical species and functional groups. Therefore, mid-infrared hyperspectral imaging is one of the most powerful and promising candidates for chemical imaging using optical…

Optics · Physics 2023-07-06 Yue Zhao , Shota Kusama , Yuji Furutani , Wei-Hong Huang , Chih-Wei Luo , Takao Fuji

Plastic pollution has become a critical global challenge, with microplastics pervading ecosystems and entering human food chains. Effectively monitoring this widespread contamination demands rapid, reliable, and portable material…

Hyperspectral imaging (HSI) enables detailed land cover classification, yet low spatial resolution and sparse annotations pose significant challenges. We present a label-efficient framework that leverages spatial features from a frozen…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yuzhen Hu , Biplab Banerjee , Saurabh Prasad

Achieving high spatial resolution is the goal of many imaging systems. Designing a high-resolution lens with diffraction-limited performance over a large field of view remains a difficult task in imaging system design. On the other hand,…