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Medical image segmentation is fundamental to clinical decision-making, yet existing models remain fragmented. They are usually trained on single knowledge sources and specific to individual tasks, modalities, or organs. This fragmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Bangwei Guo , Yunhe Gao , Meng Ye , Difei Gu , Yang Zhou , Leon Axel , Dimitris Metaxas

Automatic segmentation of brain MR images into white matter (WM), gray matter (GM), and cerebrospinal fluid (CSF) is critical for tissue volumetric analysis and cortical surface reconstruction. Due to dramatic structural and appearance…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Xiaoyang Chen , Jinjian Wu , Wenjiao Lyu , Yicheng Zou , Kim-Han Thung , Siyuan Liu , Ye Wu , Sahar Ahmad , Pew-Thian Yap

Prompt learning has demonstrated impressive efficacy in the fine-tuning of multimodal large models to a wide range of downstream tasks. Nonetheless, applying existing prompt learning methods for the diagnosis of neurological disorder still…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Liang Peng , Songyue Cai , Zongqian Wu , Huifang Shang , Xiaofeng Zhu , Xiaoxiao Li

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Brain tumor segmentation is crucial for accurate diagnosisand treatment planning, but the small size and irregular shapeof tumors pose significant challenges. Existing methods of-ten fail to effectively incorporate medical domain…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Yongheng Sun , Mingxia Liu , Chunfeng Lian

Recognizing multiple labels of an image is a practical yet challenging task, and remarkable progress has been achieved by searching for semantic regions and exploiting label dependencies. However, current works utilize RNN/LSTM to…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Tianshui Chen , Liang Lin , Riquan Chen , Xiaolu Hui , Hefeng Wu

Deep learning models usually require sufficient training data to achieve high accuracy, but obtaining labeled data can be time-consuming and labor-intensive. Here we introduce a template-based training method to train a 3D U-Net model from…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Fang-Cheng Yeh

The task of medical image segmentation commonly involves an image reconstruction step to convert acquired raw data to images before any analysis. However, noises, artifacts and loss of information due to the reconstruction process are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Qiaoying Huang , Xiao Chen , Dimitris Metaxas , Mariappan S. Nadar

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Medical image segmentation is a fundamental task for medical image analysis and surgical planning. In recent years, UNet-based networks have prevailed in the field of medical image segmentation. However, convolution-neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Xin You , Junjun He , Jie Yang , Yun Gu

Accurate segmentation of MR brain tissue is a crucial step for diagnosis,surgical planning, and treatment of brain abnormalities. However,it is a time-consuming task to be performed by medical experts. So, automatic and reliable…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Yang Deng , Yao Sun , Yongpei Zhu , Mingwang Zhu , Wei Han , Kehong Yuan

The human brain undergoes dynamic, potentially pathology-driven, structural changes throughout a lifespan. Longitudinal Magnetic Resonance Imaging (MRI) and other neuroimaging data are valuable for characterizing trajectories of change…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Agampreet Aulakh , Nils D. Forkert , Matthias Wilms

In this paper we propose a deep learning approach for segmenting sub-cortical structures of the human brain in Magnetic Resonance (MR) image data. We draw inspiration from a state-of-the-art Fully-Convolutional Neural Network (F-CNN)…

Computer Vision and Pattern Recognition · Computer Science 2016-02-08 Mahsa Shakeri , Stavros Tsogkas , Enzo Ferrante , Sarah Lippe , Samuel Kadoury , Nikos Paragios , Iasonas Kokkinos

Neurological conditions, such as Alzheimer's Disease, are challenging to diagnose, particularly in the early stages where symptoms closely resemble healthy controls. Existing brain network analysis methods primarily focus on graph-based…

Neurons and Cognition · Quantitative Biology 2025-05-20 Jiaxing Xu , Kai He , Yue Tang , Wei Li , Mengcheng Lan , Xia Dong , Yiping Ke , Mengling Feng

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

Accurate and reliable brain tumor segmentation is a critical component in cancer diagnosis, treatment planning, and treatment outcome evaluation. Build upon successful deep learning techniques, a novel brain tumor segmentation method is…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Xiaomei Zhao , Yihong Wu , Guidong Song , Zhenye Li , Yazhuo Zhang , Yong Fan

Background: Brain tumor segmentation requires precise delineation of hierarchical structures from multi-sequence MRI. However, existing deep learning methods primarily rely on visual features, showing insufficient discriminative power in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Mingda Zhang , Kaiwen Pan
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